| Dream Clean Holiday LET Cleaning Ltd | Administrative & support | 2024 |
| Dream Dental Limited | Health & social care | 2023 |
| Dream FX Limited | Information & communication | 2010 |
| Dream Nail Bar Ltd | Other services | 2025 |
| Dreamglide UK Ltd | Wholesale & retail | 2025 |
| Dreaminn Limited | Real estate | 2019 |
| Dreamscape Corporation Limited | Information & communication | 2013 |
| Dreamscape Limited | Extraterritorial | 2016 |
| Dreamscape-Web Limited | Information & communication | 1999 |
| Dreamy MAY Limited | Wholesale & retail | 2025 |
| Dress UP and Dream Parties Ltd | Arts & recreation | 2025 |
| Drew Gibson Photography Ltd | Professional & scientific | 2013 |
| Drftclothing Ltd | Wholesale & retail | 2025 |
| Driffield Dental Developments Limited | Real estate | 2021 |
| Drift Glow Ltd | Wholesale & retail | 2025 |
| Driftstone Automotive Limited | Wholesale & retail | 2025 |
| Drink ME Productions Limited | Arts & recreation | 1989 |
| Drink Q Limited | Manufacturing | 2017 |
| Drinkwater Investments Ltd | Real estate | 2014 |
| Drive Home Competitions Ltd | Wholesale & retail | 2025 |
| Driveforever Ltd | Wholesale & retail | 2021 |
| Driven Robertson Limited | Administrative & support | 2012 |
| Drivespeed Digital Limited | Professional & scientific | 2014 |
| Drivetech Group Limited | Education | 2026 |
| Driveway Mechanic Ltd | Wholesale & retail | 2023 |
| Driving Masterclass Ltd | Education | 2024 |
| Drkm Consulting & Advisory Ltd | Professional & scientific | 2026 |
| DRL Building (York) Ltd | Construction | 2022 |
| Droneuk Ltd | Other services | 2021 |
| Drozdovs Services Ltd | Manufacturing | 2025 |
| DRS (York) Limited | Wholesale & retail | 2014 |
| DRT Limited | Health & social care | 2007 |
| DRT Trailers Limited | Manufacturing | 2010 |
| Drumalane Group Limited | Professional & scientific | 2024 |
| Drumup Consulting Ltd | Professional & scientific | 2024 |
| Drury Consulting Ltd | Professional & scientific | 2012 |
| Drvn Golf Ltd | Wholesale & retail | 2024 |
| DRY Land Developments Ltd | Administrative & support | 1981 |
| Dryden Landscaping Limited | Administrative & support | 2021 |
| Drydrop Co. Limited | Wholesale & retail | 2025 |
| Dryfix Preservation Ltd | Construction | 2008 |
| DS Kanagasabai Ltd | Professional & scientific | 2015 |
| DSD Waste Solutions Ltd | Water & waste | 2020 |
| DSE Paint Works Limited | Wholesale & retail | 2017 |
| DSH Gardening and Maintenance Ltd | Administrative & support | 2024 |
| DSM Property Services Ltd. | Real estate | 2018 |
| Dsps Investments Ltd | Real estate | 2020 |
| DSR Roofing York Ltd | Construction | 2026 |
| Dsyconsulting Ltd | Professional & scientific | 2025 |
| DT PT Limited | Professional & scientific | 2019 |
| DT Sports Medicine Ltd | Health & social care | 2023 |
| DTR Properties Limited | Real estate | 2007 |
| Dual Invest Limited | Other services | 2022 |
| DUB Construction Housing York Ltd | Administrative & support | 2021 |
| Duck EGG Quilts Limited | Arts & recreation | 2024 |
| Duck Shack Ltd | Hospitality | 2023 |
| Duck Wing Homes Ltd | Real estate | 2022 |
| Dudley Dronfield Limited | Professional & scientific | 2015 |
| Dudley Hill Farm Ltd | Arts & recreation | 2023 |
| Dufour Nordend Ltd | Information & communication | 2011 |
| Dufton Environmental Limited | Professional & scientific | 2022 |
| Duggleby Stephenson LLP | | 2018 |
| Duloc Ltd | Real estate | 2025 |
| Dunbrook Harton Limited | Professional & scientific | 2024 |
| Duncan Energy Holdings Limited | Professional & scientific | 2013 |
| Duncan Engineering & Design Limited | Construction | 2007 |
| Duncan Plumbing, Heating & Electrics Limited | Construction | 2006 |
| Duncan Renewable Investments Limited | Professional & scientific | 2013 |
| Duncan Renewable Power Limited | Manufacturing | 2020 |
| Dunchurch Fields (Dunchurch) Management Company Limited | Households | 2025 |
| Duncombe Autos Ltd | Wholesale & retail | 2020 |
| Duncombe Place Management Company Limited | Professional & scientific | 2003 |
| Duncombe Place Masonic Hall Company Limited | Real estate | 2005 |
| Dunelm Farming Limited | Agriculture & fishing | 2000 |
| Dunewey Limited | Real estate | 2017 |
| Dunholme Grange Limited | Agriculture & fishing | 2017 |
| Dunning Construction Limited | Construction | 2018 |
| Dunnington (Management Company) Limited | Professional & scientific | 2013 |
| Dunnington Children | Education | 2002 |
| Dunnington Developments Limited | Construction | 2019 |
| Dunnington Electricals Ltd | Construction | 2009 |
| Dunnington Landscapes Ltd | Administrative & support | 2021 |
| Dunnington Motor Care Limited | Administrative & support | 2017 |
| Dunnington Sports Club Limited | Arts & recreation | 2010 |
| Dunnington Takeaway Ltd | Hospitality | 2024 |
| Durable Value Ltd | Professional & scientific | 2023 |
| Duran Fentiman Limited | Arts & recreation | 2014 |
| Durham Grange Limited | Real estate | 1997 |
| Durkin Gate Automation Ltd | Construction | 2024 |
| Durning Road RTM Company Limited | Households | 2025 |
| Duro Construct Limited | Construction | 2019 |
| Durrant Software Limited | Information & communication | 1991 |
| Dusk & Dawn International Limited | Manufacturing | 2024 |
| Dusk Property Ltd | Construction | 2024 |
| Dusk RP Ltd | Hospitality | 2025 |
| Dusk Studios Digital Ltd | Information & communication | 2025 |
| Dutch Barn Media and Entertainment Limited | Arts & recreation | 2024 |
| Dutch Nurseries Limited | Real estate | 2010 |
| Dutchy Limited | Information & communication | 2026 |
| Dvam Ltd | Financial services | 2024 |