| Dikeland Limited | Financial services | 2021 |
| Dimetime Limited | Wholesale & retail | 2001 |
| Dingham Propco Limited | Real estate | 2022 |
| Dining by Ashley Hyde Ltd | Extraterritorial | 2025 |
| Dining by Matthew Hyde Ltd | Hospitality | 2019 |
| Dinky Groves Day Nursery Ltd | Health & social care | 2021 |
| Dinky Groves OUT of School Club Ltd | Health & social care | 2024 |
| Dinner Box Boroughbridge Ltd | Hospitality | 2017 |
| Dino Developments Limited | Real estate | 2019 |
| Dinyd Limited | Health & social care | 2019 |
| Diode Displays Ltd | Professional & scientific | 2022 |
| DIP and DOT Ltd | Information & communication | 2024 |
| Dipju Design Ltd | Professional & scientific | 2023 |
| Dipstakes Limited | Arts & recreation | 2025 |
| Direct Deliveries (Ryedale) Limited | Transport & logistics | 2018 |
| Direct Jointing & Power Services Ltd | Construction | 2023 |
| Direct Life and Pension Services Limited | Financial services | 1990 |
| Direct Life Limited | Professional & scientific | 2005 |
| Direct Life Quote Holdings Limited | Financial services | 2016 |
| Director Pensions Limited | Financial services | 2018 |
| Directors Box Limited | Information & communication | 2023 |
| Dirtyolive Ltd | Hospitality | 2026 |
| Discoduck (DJ) Ltd | Arts & recreation | 2022 |
| Discount Roofing and Building Supplies Limited | Wholesale & retail | 1985 |
| Discovery Fine Arts | Wholesale & retail | 1972 |
| Discreet Aesthetics Limited | Other services | 2021 |
| Distance Cert Ltd | Education | 2021 |
| Distinct Property Solutions Limited | Construction | 2014 |
| Distinction Energy Limited | Professional & scientific | 2016 |
| Distinctive Cars York Limited | Wholesale & retail | 2017 |
| Distinctive Events Limited | Arts & recreation | 2022 |
| Disturb Projects Ltd | Professional & scientific | 2012 |
| Ditty Ltd | Wholesale & retail | 2024 |
| Divergent FC Ltd | Education | 2026 |
| Divert Ltd | Water & waste | 2020 |
| Divert Waste Ltd | Professional & scientific | 2021 |
| Divine Righteous Health Care Solutions Ltd | Administrative & support | 2024 |
| Divorce Clarity UK Ltd | Information & communication | 2026 |
| Dixie Hair & Beauty Ltd | Other services | 2022 |
| Dixons Yard Management Limited | Households | 1989 |
| DJ Shepherd & Associates Ltd | Public administration | 2023 |
| DJ Smart Drivers Ltd | Transport & logistics | 2025 |
| DJB Photography Limited | Professional & scientific | 2007 |
| DJC Trading Finest Ltd | Wholesale & retail | 2025 |
| DJC Trading Spirits Ltd | Wholesale & retail | 2022 |
| DJH York Joinery Ltd | Construction | 2024 |
| DJK Holdings York Ltd | Real estate | 2024 |
| Djmes Investments Ltd | Financial services | 2024 |
| Djmes Ltd | Professional & scientific | 2021 |
| DJR Lettings Limited | Real estate | 2019 |
| Djrs Yorkshire Ltd | Wholesale & retail | 2013 |
| DJW Packaging Limited | Wholesale & retail | 2017 |
| DK Fitness Holdings Ltd | Professional & scientific | 2025 |
| DK Tenants Limited | Construction | 2002 |
| DK. Nodd Ltd | Transport & logistics | 2020 |
| DKF Holdings Limited | Financial services | 2023 |
| Dkwt Limited | Health & social care | 2024 |
| DL Pet Solutions Limited | Wholesale & retail | 2020 |
| DL5 Limited | Hospitality | 2010 |
| DLG Property Solutions Limited | Construction | 2009 |
| DLS Electrical Engineering Ltd | Professional & scientific | 2013 |
| DLT Apps Limited | Information & communication | 2018 |
| DLX Dent Ltd | Health & social care | 2023 |
| DM Joinery and Interiors Ltd | Construction | 2025 |
| DM Motor Services Limited | Manufacturing | 2015 |
| DM Plumbing and Heating Services Limited | Construction | 2015 |
| DM Services (York) Ltd | Administrative & support | 2013 |
| DMB Rail Consultancy Limited | Professional & scientific | 2016 |
| DMC (2022) Ltd | Information & communication | 2022 |
| DMH Electrical Services Ltd | Energy | 2023 |
| DMK Equestrian Ltd | Arts & recreation | 2026 |
| Dmkh Consulting Ltd | Real estate | 2014 |
| DMM Services UK Ltd | Construction | 2025 |
| DMP Tyres Ltd | Wholesale & retail | 2019 |
| DMU Designs Limited | Professional & scientific | 2010 |
| DNA Central Ltd | Hospitality | 2023 |
| DNA Developments (York) Limited | Construction | 2016 |
| DNA Gym Ltd | Education | 2024 |
| DNA MMA Ltd | Education | 2025 |
| DNA York Ltd | Hospitality | 2018 |
| DNB Home and Stone Limited | Construction | 2013 |
| DNB Stone Fireplaces Limited | Manufacturing | 2019 |
| DO Make Limited | Professional & scientific | 2014 |
| Dobson Motors Ltd | Wholesale & retail | 2003 |
| Dock Savvy Limited | Other services | 2024 |
| Docsurge Limited | Real estate | 2000 |
| Documetrics Control Ltd | Information & communication | 2025 |
| Docuzen Solutions Limited | Information & communication | 2025 |
| Doeg Global Ventures Ltd | Information & communication | 2017 |
| Dogan Food Centre Ltd | Wholesale & retail | 2017 |
| Doggie and Moggie Limited | Other services | 2016 |
| Dogh Limited | Hospitality | 2022 |
| Dogobees Eco Hairdressers Ltd | Other services | 2019 |
| Dogobees Retail Ltd | Wholesale & retail | 2023 |
| Dogstar Industries Limited | Information & communication | 2012 |
| Dohertyharrison Enterprise Ltd | Wholesale & retail | 2020 |
| Doinadent Limited | Wholesale & retail | 2025 |
| Doing Good Work Ltd | Professional & scientific | 2026 |
| Dojo Films Ltd | Information & communication | 2019 |
| Dojo Partners Ltd | Information & communication | 2022 |