| Sinko Transport Ltd | Transport & logistics | 2018 |
| Sintonsand Gundogs Limited | Other services | 2015 |
| Sipaco Limited | Information & communication | 2016 |
| SIS-60 Trans Ltd | Transport & logistics | 2020 |
| Sisemen Limited | Real estate | 2014 |
| SIT and BEE Therapies Ltd | Health & social care | 2026 |
| Sitone Computer Services Ltd | Information & communication | 2007 |
| SIX Ways Properties LLP | | 2004 |
| Sixty and Worcestershire Motor Club Limited (the) | Arts & recreation | 1970 |
| Sixty and Worcestershire Rally Club Limited | Arts & recreation | 1990 |
| Sixty Ventures Limited | Professional & scientific | 2022 |
| Sixways Medical Limited | Health & social care | 2022 |
| Sixways Property Development Ltd | Construction | 2025 |
| Sixways Property Services Ltd | Construction | 2014 |
| Sixways Stadium Limited | Real estate | 2022 |
| SJ Storer Properties UK Ltd | Real estate | 2026 |
| SJ Theatre Arts Academy CIC | Arts & recreation | 2026 |
| SJ Untamed Ltd | Information & communication | 2024 |
| SJ3D Ltd | Manufacturing | 2018 |
| SJB Securities Limited | Financial services | 2013 |
| SJH Plumbing & Heating Ltd | Construction | 2014 |
| SJK Lone Limited | Hospitality | 2015 |
| SJL (Worcester) Ltd | Financial services | 2015 |
| SJL Limited | Professional & scientific | 2020 |
| SKA Logistics Ltd | Other services | 2025 |
| Skas Solutions Limited | Information & communication | 2014 |
| Skate Sale Limited | Extraterritorial | 2008 |
| Sketchy Print Co Limited | Manufacturing | 2020 |
| SKI Astons Ltd | Administrative & support | 2009 |
| Skillman Aesthetics Limited | Health & social care | 2015 |
| Skinspace Global Limited | Wholesale & retail | 2026 |
| SKN House Ltd | Real estate | 2019 |
| Sky Heights Management Company Limited | Households | 2021 |
| Skye Ridge Retreats Ltd | Real estate | 2025 |
| Skyharrier Ltd | Professional & scientific | 2020 |
| Skylark Carbon Limited | Agriculture & fishing | 2019 |
| Skylark Land and Homes Ltd | Real estate | 2022 |
| Skylets Ltd | Real estate | 2014 |
| Skyline Activities Limited | Administrative & support | 2013 |
| Skyline Blue Properties Ltd | Real estate | 2020 |
| Skyline Fireworks Ltd | Wholesale & retail | 2024 |
| Skyline Glass Spaces Ltd | Construction | 2025 |
| Skyventure International (UK) Limited | Administrative & support | 2003 |
| SL Real Estate Ltd | Real estate | 2023 |
| Slate Health Group Limited | Health & social care | 2026 |
| Slayers Bay Limited | Arts & recreation | 2006 |
| Sleepy Weasel Ltd | Wholesale & retail | 2008 |
| SLF Property & Asset Group Ltd | Construction | 2025 |
| SLH Healthcare UK Ltd | Health & social care | 2022 |
| Slick Group Ltd | Wholesale & retail | 2021 |
| Slick Homes Ltd | Hospitality | 2025 |
| SLM HR Limited | Administrative & support | 2014 |
| SLR Coffee Point Ltd | Hospitality | 2025 |
| SLT Risk Solutions Ltd | Financial services | 2023 |
| SM Corporate Events Limited | Administrative & support | 2022 |
| SM Plastering Ltd | Construction | 2016 |
| SMA SUB Limited | Hospitality | 2024 |
| Smart DIG Limited | Construction | 2013 |
| Smart Gold Ltd | Wholesale & retail | 2019 |
| Smart Group Transport Ltd | Transport & logistics | 2021 |
| Smart Insolvency Solutions Limited | Professional & scientific | 2012 |
| Smart Installations Midlands Ltd | Construction | 2025 |
| Smart Installations Mids Limited | Administrative & support | 2019 |
| Smart Money Made Easy Ltd | Information & communication | 2021 |
| Smart Polak Ltd | Information & communication | 2014 |
| Smart Positioning Limited | Administrative & support | 2017 |
| Smashing UK Productions Limited | Information & communication | 2019 |
| SMB Coldstores Limited | Construction | 2006 |
| SMB Electrical Solutions Limited | Energy | 2015 |
| Smch Services Ltd | Construction | 2016 |
| SMH IT Solutions Limited | Information & communication | 2021 |
| Smith Ivanson Limited | Professional & scientific | 2003 |
| SML Vehicle Rental Limited | Transport & logistics | 2010 |
| Smokey Vepe Ltd | Wholesale & retail | 2026 |
| SMP Builders Ltd | Construction | 2007 |
| Smugglers Distillery Limited | Extraterritorial | 2023 |
| SMY Developments Limited | Construction | 2026 |
| Smythe Property Holdings Limited | Wholesale & retail | 2018 |
| Smythe Property Limited | Wholesale & retail | 2018 |
| Snailham & Co Ltd | Professional & scientific | 2016 |
| Snap Electrical (Worcester) Ltd | Construction | 2021 |
| Snap Geospatial Solutions Limited | Information & communication | 2026 |
| Snapdragon Landscaping Ltd | Administrative & support | 2026 |
| SND Construction Projects Ltd | Construction | 2018 |
| Sngs Hospitality Ltd | Hospitality | 2025 |
| Snikket Community Interest Company | Information & communication | 2020 |
| Snow Pond UK Limited | Manufacturing | 2013 |
| Snowscape Limited | Administrative & support | 1999 |
| SNS Properties Ltd | Real estate | 2018 |
| SNS Services Ltd | Administrative & support | 2026 |
| SNZ Restaurants Ltd | Hospitality | 2025 |
| SO Aesthetics Bewdley Limited | Health & social care | 2017 |
| SO Aesthetics Cirencester Limited | Health & social care | 2026 |
| SO Living Support CIC | Real estate | 2026 |
| SO Podiatry Limited | Health & social care | 2017 |
| SO Skin Worcester Ltd | Other services | 2019 |
| Soar TPI (Holdings) Ltd | Administrative & support | 2014 |
| Social and Co 2020 (UK) Ltd | Professional & scientific | 2020 |
| Social Sense Marketing Limited | Professional & scientific | 2018 |
| Social Work Assessment Specialists Ltd | Health & social care | 2020 |