| Shared Days Ltd | Health & social care | 2017 |
| Shared Equity Securities Limited | Real estate | 1998 |
| Shares and Investment Lifestyle Limited | Financial services | 2020 |
| Sharp Monkeys Limited | Information & communication | 2005 |
| Sharpe Supply Chain Solutions Limited | Professional & scientific | 2012 |
| Sharps Investment Management Limited | Financial services | 2013 |
| Sharwfair Ltd | Health & social care | 2020 |
| Shaun Weston Glazing Ltd | Construction | 2026 |
| Shaun's Gardening & Landscaping Limited | Administrative & support | 2017 |
| SHE Gains Online Limited | Administrative & support | 2024 |
| SHE Hair (Worcester) Limited | Other services | 2026 |
| SHE Solutions Limited | Professional & scientific | 2003 |
| Shea Consulting Limited | Professional & scientific | 2023 |
| Shearline Steels Limited | Manufacturing | 1979 |
| Shearman Podiatry Ltd | Health & social care | 2024 |
| Sheds ARE US Limited | Manufacturing | 2014 |
| Sheep NO1 Limited | Construction | 2012 |
| Shelley Davies Consultancy Ltd. | Professional & scientific | 2016 |
| Shelsley Walsh Hill Climb PLC | Arts & recreation | 2004 |
| Shelter-Adams Limited | Construction | 2014 |
| Shelton & Lines Ltd | Real estate | 2012 |
| Shenzgrillz Limited | Hospitality | 2025 |
| Sheppard Property Holdings Ltd | Real estate | 2022 |
| Sheraton Healthcare Ltd | Health & social care | 2020 |
| Sherbet Donkey Marketing Limited | Professional & scientific | 2020 |
| Sherriff's Gate Developments Limited | Construction | 2018 |
| Shield Construction Consultants Limited | Administrative & support | 2014 |
| Shield Roofing Ltd | Construction | 2021 |
| Shimla Kebab & Grill Limited | Hospitality | 2015 |
| Shipix Ltd | Wholesale & retail | 2025 |
| Shire Bath Re-Enamelling Limited | Construction | 2014 |
| Shire Disposables Limited | Wholesale & retail | 2024 |
| Shire Fuels Heating Services Ltd | Construction | 2026 |
| Shire Photography and Property Services Limited | Professional & scientific | 2018 |
| Shire Tanks Ltd | Manufacturing | 2023 |
| Shire Tiling & Building Services Limited | Construction | 2011 |
| Shires Farm Limited | Agriculture & fishing | 1996 |
| Shirtcraft Ltd | Administrative & support | 2017 |
| Shooting Stars Properties Ltd | Real estate | 2019 |
| Shopzilla Ltd | Wholesale & retail | 2025 |
| Shortso Threads Ltd | Manufacturing | 2025 |
| Shotwize Limited | Information & communication | 2009 |
| Shoulton Investments Ltd | Real estate | 2007 |
| Showcase Your Business Ltd | Manufacturing | 2026 |
| Showstage Limited | Construction | 2024 |
| Showtime Group Inc. UK Ltd | Administrative & support | 2026 |
| Shranik Ltd | Information & communication | 2025 |
| Shreem Holdings Ltd | Financial services | 2022 |
| Shrewsbury Care Ltd | Professional & scientific | 2015 |
| Shui Style Limited | Information & communication | 2015 |
| Si-Can Engineering Ltd. | Professional & scientific | 2000 |
| Siarl Ltd | Professional & scientific | 2026 |
| Sical Construction Ltd | Construction | 2025 |
| Sidbury Gate Estates Limited | Real estate | 2017 |
| Sidbury Limited | Hospitality | 2025 |
| Sidell Surveyors Ltd | Professional & scientific | 2026 |
| Sidetracked Limited | Information & communication | 2012 |
| Sidlerfy Limited | Education | 2012 |
| Sierra CP Engineering Limited | Manufacturing | 1993 |
| Sigma Wellness Ltd | Health & social care | 2022 |
| Sign City Worcester Ltd | Manufacturing | 2022 |
| Signature Brows Ltd | Other services | 2022 |
| Signature Diamonds Limited | Manufacturing | 2024 |
| Signature Recruitment Consultancy Ltd | Administrative & support | 2017 |
| Signature Shoots Ltd | Professional & scientific | 2024 |
| Signature Signs & Graphics Ltd | Professional & scientific | 2025 |
| Silmarillion Consulting Limited | Information & communication | 2005 |
| Silver Resources Ltd | Other services | 2019 |
| Silver Spring Resources Ltd | Other services | 2019 |
| Silverstone Ventures Ltd | Other services | 2025 |
| Silverwing Solutions Limited | Professional & scientific | 2025 |
| Silvington Properties Ltd | Real estate | 2022 |
| SIM Cargo Ltd | Transport & logistics | 2025 |
| SIM Shoots Ltd | Arts & recreation | 2025 |
| Simmons Turner Finance Limited | Real estate | 2015 |
| Simms Building Services ( UK ) Ltd | Construction | 2018 |
| Simon Baker Plumbing & Heating Limited | Construction | 2011 |
| Simon Carmichael International Group Limited | Manufacturing | 2010 |
| Simon Hutchison Limited | Information & communication | 2015 |
| Simon Read Limited | Construction | 2012 |
| Simon York Consulting Ltd | Professional & scientific | 2023 |
| Simple Design Works Ltd | Professional & scientific | 2014 |
| Simple Law Ltd | Professional & scientific | 2020 |
| Simple Soft Solutions Ltd | Information & communication | 2025 |
| Simplicity Mortgages Limited | Financial services | 2020 |
| Simply Assist Limited | Professional & scientific | 2012 |
| Simply Beautiful Investments Limited | Real estate | 2022 |
| Simply Driven Ltd | Transport & logistics | 2024 |
| Simply GET Results Limited | Information & communication | 2016 |
| Simply People HR Ltd | Administrative & support | 2019 |
| Simply Radio Limited | Information & communication | 2017 |
| Simply Recipes Ltd | Information & communication | 2023 |
| Simply the Best Care Ltd | Health & social care | 2020 |
| Simson Group Holdings Limited | Financial services | 2026 |
| Simson Property Group Limited | Real estate | 2025 |
| Sinclair Day Accountancy Ltd | Professional & scientific | 2012 |
| Sinclair Wilde Limited | Administrative & support | 2016 |
| Sinfield Cars Limited | Wholesale & retail | 2008 |
| Sinford (Plant Sales) Limited | Administrative & support | 1982 |
| Sinh Limited | Hospitality | 2012 |