| DBW Consulting Ltd | Professional & scientific | 2024 |
| DC Consulting Services Ltd | Professional & scientific | 2018 |
| DC Global Consultancy Ltd | Professional & scientific | 2024 |
| DCK Holdings Limited | Real estate | 2024 |
| DCL Interpreting Limited | Professional & scientific | 2019 |
| DCS Bespoke Properties Ltd | Hospitality | 2022 |
| DDC Auto Services Ltd | Wholesale & retail | 2019 |
| DDH Group Ltd | Real estate | 2021 |
| Ddmr (Different Dimensions in Music and Recording) Limited | Information & communication | 2011 |
| DE Valsair Group Limited | Wholesale & retail | 2015 |
| Deaf Student Solutions Limited | Education | 2012 |
| Deakin Melville Ltd | Real estate | 2022 |
| Debasish Biswas Consultancy Services Limited | Professional & scientific | 2018 |
| Deborah Alfa Limited | Other services | 2019 |
| Debrief Properties Ltd | Real estate | 2021 |
| Deca DEV Ltd | Professional & scientific | 2025 |
| Decapende Limited | Real estate | 2021 |
| Decentralised Engineering Ltd | Professional & scientific | 2019 |
| Dechem Properties Limited | Real estate | 2021 |
| Deck Chair Holdings Ltd | Administrative & support | 2018 |
| Deckswap Limited | Wholesale & retail | 2026 |
| Dedicated Parking Solutions Limited | Other services | 2018 |
| DEE Catering Ltd | Hospitality | 2018 |
| DEE Consultancy Solutions Ltd | Professional & scientific | 2025 |
| DEE GP Ltd | Health & social care | 2023 |
| DEE Motor Co Limited | Real estate | 2003 |
| DEE Motor Company Services Limited | Wholesale & retail | 2021 |
| DEE View Developments Limited | Real estate | 2002 |
| DEE View House Management Company Limited | Real estate | 2002 |
| Deedale Financial Services Limited | Financial services | 2007 |
| Deep Blue Communications Ltd | Professional & scientific | 2010 |
| Deeside Finishing Supplies Limited | Manufacturing | 2010 |
| Deeside Laundry Company(West Kirby)Limited(The) | Other services | 1912 |
| Deeside Tackle Shop Limited | Wholesale & retail | 2021 |
| Defying the Normal Limited | Professional & scientific | 2022 |
| Delamere Cafe Limited | Real estate | 2005 |
| DELI2DESK Limited | Hospitality | 2019 |
| Deliverance Software Limited | Information & communication | 2003 |
| Delphine Wilson Knitwear Limited | Manufacturing | 2006 |
| Delta Services (GB) Holdings Ltd | Financial services | 2025 |
| Delta Services (GB) Limited | Wholesale & retail | 2001 |
| Delta Spark Electrical Ltd | Construction | 2025 |
| Deluean Roofing Solutions Limited | Construction | 2025 |
| Demir Properties and Developments Ltd | Households | 2025 |
| Dempsey Legal Limited | Professional & scientific | 2016 |
| Densurance Ltd | Health & social care | 1997 |
| Dental Health Club Ltd | Health & social care | 2022 |
| Derek Armstrong Builders Limited | Construction | 1999 |
| Derek Massey & Sons Limited | Extraterritorial | 2003 |
| Dering Property Investments Ltd | Real estate | 2024 |
| Derwent House Freehold Limited | Real estate | 2012 |
| DES Mcnamara & Partners Limited | Extraterritorial | 2018 |
| Design Aesthetics Cheshire Ltd | Health & social care | 2023 |
| Design by Demmerling Ltd | Professional & scientific | 2023 |
| Design Coordination Limited | Construction | 2016 |
| Design in Safety Limited | Construction | 2025 |
| Design Stitch SEW Limited | Manufacturing | 2015 |
| Design Windows & Doors Limited | Construction | 2016 |
| Designertech Ltd | Administrative & support | 2011 |
| Desnas Limited | Wholesale & retail | 1997 |
| Despena Nexus Ltd | Administrative & support | 2026 |
| Despite the Monkey Limited | Arts & recreation | 2019 |
| Destination Anywhere Limited | Administrative & support | 2004 |
| Deuce Facilities Management Limited | Administrative & support | 2026 |
| Deva Plumbing & Heating Spares Ltd | Wholesale & retail | 2023 |
| Deva Podiatry Limited | Health & social care | 2026 |
| Devaney Medical LLP | | 2013 |
| Devatec Limited | Real estate | 2004 |
| Developing Transport Solutions Ltd | Professional & scientific | 2018 |
| Development Contours Ltd | Professional & scientific | 2017 |
| Device Design International Limited | Administrative & support | 2017 |
| Devonshire Thermal Insulations Ltd | Construction | 2000 |
| Dewan Ventures Limited | Hospitality | 2015 |
| DG Design Services Limited | Construction | 2021 |
| DGB Sols Limited | Professional & scientific | 2013 |
| DGI Consultancy Limited | Professional & scientific | 2019 |
| DGL2017 Limited | Administrative & support | 2017 |
| DGT Brickwork Ltd | Construction | 2022 |
| DH Technology Ltd | Information & communication | 2019 |
| Dhaka Takeaway Limited | Hospitality | 1993 |
| DHI VUE Limited | Information & communication | 2023 |
| Dhiraj Gupta Limited | Health & social care | 2017 |
| DHO Energy Limited | Professional & scientific | 2025 |
| DHR Distributions Limited | Wholesale & retail | 2025 |
| Dhuma Wirral Ltd | Hospitality | 2024 |
| Diado Ltd | Wholesale & retail | 2024 |
| Dial House Management Company Limited | Real estate | 2003 |
| Diamond Health Limited | Wholesale & retail | 2004 |
| Dianthas Ltd | Administrative & support | 2008 |
| DIE4TECHNOLOGY Limited | Professional & scientific | 2011 |
| DIG & Shift Groundworks and Plant Hire Limited | Construction | 2020 |
| Digi Tech Care Ltd | Manufacturing | 2023 |
| Digital Adaption Ltd | Professional & scientific | 2025 |
| Digital Care Hub C.I.C. | Information & communication | 2023 |
| Digital Communities Connect CIC | Education | 2024 |
| Digital Core Consulting UK Ltd | Professional & scientific | 2026 |
| Digital Delivery Solutions Ltd | Information & communication | 2020 |
| Digital Flapjack Ltd | Information & communication | 2009 |
| Digital Mastery Ltd | Professional & scientific | 2020 |
| Digital Tax Bookkeeping Limited | Extraterritorial | 2017 |