| CULTIV8 Lifestyle Ltd | Wholesale & retail | 2018 |
| Cultivate 2 Educate CIC | Public administration | 2025 |
| Cultural Wine Ltd | Wholesale & retail | 2020 |
| Culture and Leadership Labs Limited | Professional & scientific | 2024 |
| Culture Camp Ltd | Administrative & support | 2025 |
| Culverstons Limited | Professional & scientific | 2014 |
| Cumpsty Limited | Real estate | 2017 |
| Cumulus Holdings Limited | Financial services | 2015 |
| Cuninghame Design Limited | Professional & scientific | 2015 |
| Curious Pastimes Limited | Administrative & support | 1996 |
| Curnan's UK Ltd | Construction | 2013 |
| Curtain Wall & Cladding Ltd | Construction | 2020 |
| Cusato Timber Ltd | Wholesale & retail | 2014 |
| Custodian Electrical Services Limited | Construction | 2018 |
| Custom Floors (North West) Limited | Construction | 2012 |
| Custom Funding Limited | Professional & scientific | 1999 |
| Custom House Interiors Limited | Administrative & support | 2008 |
| Custom Plumbing Limited | Construction | 2022 |
| Customer Shaped Ltd | Professional & scientific | 2015 |
| CW Adhd Consultancy Ltd | Health & social care | 2025 |
| CW Web Design Limited | Information & communication | 2017 |
| CWB Group Ltd | Wholesale & retail | 2024 |
| CWB Property Group Ltd | Real estate | 2024 |
| CWB Property Investments Ltd | Real estate | 2025 |
| CWD H&B Ltd | Wholesale & retail | 2023 |
| Cwdysart Properties Limited | Real estate | 2023 |
| Cyberbird Limited | Financial services | 1994 |
| Cynch Limited | Information & communication | 2019 |
| Cyrilsons Crew Transfer Vessels Limited | Transport & logistics | 2025 |
| Cyrilsons Entertainment Ltd | Hospitality | 2023 |
| Cyrilsons Properties Ltd | Real estate | 2022 |
| Cyrilsons Renewables Limited | Professional & scientific | 2020 |
| D & B Inspection Services Ltd | Manufacturing | 2022 |
| D & G Menswear Limited | Wholesale & retail | 2025 |
| D & L O`Neill (Bookeeping) Limited | Professional & scientific | 2008 |
| D & L O`Neill (Paye) Limited | Professional & scientific | 2008 |
| D & L O`Neill (Taxis) Limited | Professional & scientific | 2008 |
| D Creationz & Co UK Ltd | Other services | 2023 |
| D Davies Projects Ltd | Administrative & support | 2023 |
| D Gooding Ltd | Transport & logistics | 2014 |
| D H Services (NW) Limited | Construction | 2019 |
| D Light Access Ltd | Mining & quarrying | 2011 |
| D M Plant Limited | Construction | 2003 |
| D-Ways Ltd | Education | 2017 |
| D. Hughes Associates Limited | Education | 2015 |
| D.B Medical Supplies Ltd | Wholesale & retail | 2025 |
| D.M. Kaye (Wirral) Limited | Real estate | 1973 |
| Dacrestreet Estates Limited | Real estate | 1972 |
| Daedalus Homes Limited | Construction | 2023 |
| Dagnall Innovation Limited | Administrative & support | 2023 |
| Dale Street Properties Limited | Real estate | 2014 |
| DAM Technologies Limited | Administrative & support | 2018 |
| Dames Blonde Ltd | Manufacturing | 2011 |
| Damp Survey & Training Ltd | Professional & scientific | 2024 |
| Damrod Group Ltd | Administrative & support | 2024 |
| Dan&Van Ltd | Real estate | 2020 |
| Dani Warrior of Light C.I.C. | Other services | 2024 |
| Daniel James Bathrooms Ltd | Wholesale & retail | 2023 |
| Daniel Stam & Co Limited | Real estate | 2007 |
| Danielle Keen Davis Ltd | Health & social care | 2018 |
| Danjaylai Limited | Manufacturing | 2015 |
| Danny Stephens Ltd | Other services | 2025 |
| Danu Commercial Management Consultancy Ltd. | Construction | 2017 |
| Danweld Group Ltd | Professional & scientific | 2024 |
| DAP Electrical Limited | Construction | 2015 |
| Dappological Ltd | Information & communication | 2015 |
| Dargo Property Investments Limited | Administrative & support | 2016 |
| Dark Horse Moto Ltd | Wholesale & retail | 2026 |
| Dark Studios Consulting Limited | Professional & scientific | 2025 |
| Darkaus Ltd | Arts & recreation | 2008 |
| Darling Dwellings Limited | Real estate | 2025 |
| Darrell Vaughan Thompson Ltd | Extraterritorial | 2025 |
| Dassol Limited | Information & communication | 2004 |
| Dast Mortgages Limited | Financial services | 2022 |
| Data Analyst Training Limited | Information & communication | 2020 |
| Dataguardsman Limited | Professional & scientific | 2010 |
| Datalink Technology Limited | Information & communication | 2025 |
| Dauntless Studio Ltd | Information & communication | 2022 |
| Davca Consulting Limited | Professional & scientific | 2024 |
| Dave Thomas & Co Ltd | Administrative & support | 2014 |
| David J Tinsley Training Ltd | Education | 2011 |
| David Kendall Consulting Ltd | Professional & scientific | 2020 |
| David Kingsley Limited | Real estate | 1945 |
| David Penney Procurement Solutions Ltd | Professional & scientific | 2010 |
| David Sayer Consultancy Limited | Real estate | 2018 |
| Davida Carpets & Flooring Ltd | Construction | 2021 |
| Davidjobs Ltd | Health & social care | 2014 |
| Davidson HR Services Limited | Professional & scientific | 2017 |
| Dawn Media Ltd | Professional & scientific | 2023 |
| Dawpool Farm Residents' Company Limited | Households | 1991 |
| Dawson Birkenhead Houses Limited | Financial services | 1924 |
| Dawson Decorative Coatings Ltd | Construction | 2017 |
| Dawstone Court Management (1994) Limited | Households | 1995 |
| Day Choice Convenion Store Ltd | Wholesale & retail | 2015 |
| Day Profits Ltd | Wholesale & retail | 2020 |
| Dayglow Ltd | Administrative & support | 2022 |
| Daymar (Wirral) Limited | Real estate | 1998 |
| DB & BB Developments Ltd | Construction | 2022 |
| Dbhb Consulting Ltd | Information & communication | 2012 |
| DBL MAX Limited | Other services | 2023 |