| Streetwise Lets Ltd | Real estate | 2026 |
| Streetz CIC | Other services | 2021 |
| Strength & Fitness LAB (NW) Limited | Arts & recreation | 2024 |
| Strengthen Ltd | Information & communication | 2019 |
| Strensham Electronics Limited | Manufacturing | 2015 |
| Stressless Property Ltd | Manufacturing | 2019 |
| Stretford Roofing Ltd | Construction | 2020 |
| Stretton Hall Mews Limited | Households | 1989 |
| Stretton House Cheshire Ltd | Hospitality | 2015 |
| Stretton Real Estate Investments Limited | Real estate | 2023 |
| Strick Trader Limited | Wholesale & retail | 2025 |
| Strictly Rhythm Records Limited | Extraterritorial | 2020 |
| Stride Media Limited | Professional & scientific | 2009 |
| Strider Interactive Ltd | Arts & recreation | 2024 |
| Strides Equestrian Limited | Agriculture & fishing | 2016 |
| Strike Matz UK Limited | Construction | 2022 |
| Strikeclub Ltd | Wholesale & retail | 2018 |
| Striker Academy Foundation CIC | Education | 2020 |
| Stripe Products Ltd | Construction | 2021 |
| Striped Panther Limited | Professional & scientific | 2022 |
| Strong Analytics Ltd | Administrative & support | 2021 |
| Strontium Contracts Limited | Administrative & support | 2013 |
| Stroolmount (UK) Ltd | Wholesale & retail | 2007 |
| Structural Design & Draughting Limited | Professional & scientific | 2003 |
| Struds.Net Limited | Information & communication | 2010 |
| Stryk Software Ltd | Information & communication | 2026 |
| STS Asbestos Surveyor Limited | Professional & scientific | 2017 |
| STS World 2019 Ltd | Wholesale & retail | 2019 |
| Stuart Canvas Group Limited | Manufacturing | 2006 |
| Stuart Canvas Limited | Manufacturing | 1971 |
| Stuart Howard & Co. Limited | | 1986 |
| Stuart Mechanical Engineering Limited | Administrative & support | 2016 |
| Stuart Milne Driving Services Limited | Transport & logistics | 2013 |
| Stuart Quantity Surveying Ltd | Professional & scientific | 2023 |
| Stuart Ward Investments Ltd | Real estate | 2025 |
| Stuart Wright Technical Services Ltd | Information & communication | 2014 |
| Stubbins Properties Ltd | Real estate | 2018 |
| Stud Farm Management Company Ltd | Real estate | 2007 |
| Students WHO Thrive Ltd | Education | 2026 |
| Studio 54 Tattoos Limited | Other services | 2012 |
| Studio 55 (Warrington) Limited | Other services | 2015 |
| Studio Doctors Ltd | Health & social care | 2021 |
| Studio JD Limited | Real estate | 2022 |
| Studio of Jackson Ltd | Manufacturing | 2026 |
| Studio Propolis Ltd | Manufacturing | 2020 |
| Studio S Properties Ltd | Real estate | 2025 |
| Studio Severn Ltd | Other services | 2019 |
| Studiopro Limited | Professional & scientific | 2017 |
| Stugeo Consulting Limited | Administrative & support | 2023 |
| Stura Consulting Ltd | Administrative & support | 2023 |
| Stvo Limited | Real estate | 2025 |
| Style & Comfort Interiors Limited | Wholesale & retail | 2004 |
| Style Lobster Limited | Professional & scientific | 2018 |
| Styles & Co JFC Limited | Professional & scientific | 2018 |
| Stylicon Limited | Other services | 2000 |
| Stylistic Designs Limited | Professional & scientific | 2019 |
| SU Lavercombe Consultancy Ltd | Administrative & support | 2026 |
| Subbtera 13 Ltd | Hospitality | 2023 |
| Subesh Limited | Health & social care | 2011 |
| Subport Limited | Construction | 2018 |
| Subsea Engineering Solutions Ltd | Professional & scientific | 2023 |
| Subsea Projects Services Limited | Other services | 2018 |
| Subsea Safety Solutions Ltd | Construction | 2025 |
| Subsequently Limited | Real estate | 2023 |
| Subvert Automation Ltd | Professional & scientific | 2024 |
| Subz Property Investment Ltd | Real estate | 2020 |
| Success Matters Ltd | Other services | 2019 |
| Successful Agile Transformation Limited | Professional & scientific | 2016 |
| Successful Transitions 2 Ltd | Professional & scientific | 2024 |
| Succession CFO Limited | Administrative & support | 2019 |
| Suder Properties Ltd | Real estate | 2023 |
| Sudera Law Limited | Professional & scientific | 2025 |
| Suffolk House Developments Limited | Construction | 1988 |
| Sugarev Ltd | Construction | 2020 |
| Sughra Properties Limited | Real estate | 2023 |
| Sukhmani Consulting Limited | Information & communication | 2013 |
| Sulemans Software Limited | Other services | 2018 |
| Sulis Consultancy Ltd | Information & communication | 2017 |
| Sullivans Inns Ltd | Hospitality | 2026 |
| Sullivansholdings Ltd | Financial services | 2026 |
| Sulumar Welding Services Limited | Administrative & support | 2024 |
| Summers Events & Co Ltd | Administrative & support | 2026 |
| Summers Mann Property Group Ltd | Real estate | 2026 |
| Summerseat Holdings Limited | Professional & scientific | 1920 |
| Summes Solutions Limited | Administrative & support | 2010 |
| Summit Attempt Limited | Construction | 2012 |
| Summit Heights Ltd | Wholesale & retail | 2025 |
| Summit Writing Services Limited | Extraterritorial | 2024 |
| Sumner & SON Ltd | Construction | 2026 |
| Sumptus Consulting Limited | Administrative & support | 2013 |
| Sumtimezworx Software Ltd | Information & communication | 2024 |
| Sumy Consulting Ltd | Information & communication | 2020 |
| Sun CAD Design Limited | Professional & scientific | 2016 |
| Sun Centre World Limited | Arts & recreation | 1988 |
| Sun Nails Bar Ltd | Other services | 2024 |
| Sunberry Systems Ltd | Information & communication | 2024 |
| Sunbloom AI Ltd | Information & communication | 2025 |
| Sunbloom Solutions Ltd | Information & communication | 2026 |
| Suncare Central (UK) Limited | Wholesale & retail | 2001 |
| Suncliffe Business Consultancy Limited | Administrative & support | 2015 |