| Steve Wright Consultancy Limited | Health & social care | 2017 |
| Steven Bell QS Services Ltd | Professional & scientific | 2025 |
| Steven Danks Limited | Administrative & support | 2008 |
| Steven Park Consulting Limited | Professional & scientific | 2026 |
| Steven Rogers Interiors Limited | Wholesale & retail | 2021 |
| Steven Rogers Woodflooring Limited | Wholesale & retail | 2024 |
| Steven Stuart Manufacturing Services Ltd | Hospitality | 2024 |
| Steven Thomas Just Mortgages Ltd | Financial services | 2023 |
| Steven Yates Limited | Transport & logistics | 2014 |
| Stevengrad Limited | Real estate | 2022 |
| Stevenpughuk Limited | Administrative & support | 2013 |
| Stevenson Price Limited | Information & communication | 2022 |
| Steveo Decon Work Limited | Health & social care | 2023 |
| Stewart Carter Ltd | Wholesale & retail | 2008 |
| Stewart Civil Engineering Ltd | Professional & scientific | 2019 |
| Stewart Williams Transport Ltd | Transport & logistics | 2025 |
| STG Safety Limited | Administrative & support | 2023 |
| Stheart Homes Community Interest Company | Other services | 2010 |
| Sticks (Holdings) Ltd | Professional & scientific | 2008 |
| Sticky RIB Records Limited | Arts & recreation | 2025 |
| Sticky Solutions Limited | Information & communication | 2013 |
| Stickytech Limited | Information & communication | 2011 |
| Stilwell Advisory Limited | Administrative & support | 2016 |
| Stingray Systems Limited | Information & communication | 2017 |
| Stipe Welding Limited | Professional & scientific | 2026 |
| Stirling-Gray Ltd | Other services | 2018 |
| Stitch Express Warrington Limited | Other services | 2025 |
| STM Quality Limited | Administrative & support | 2007 |
| Stoa Homes Ltd | Real estate | 2021 |
| Stobart Truckstops Limited | Transport & logistics | 2012 |
| Stocalfe Response Ltd | Administrative & support | 2019 |
| Stockan Engineering Limited | Administrative & support | 2016 |
| Stocks Commercials Ltd | Wholesale & retail | 2026 |
| Stockton Commercial Finance Ltd | Professional & scientific | 2022 |
| Stockton Feast Limited | Hospitality | 2025 |
| Stockton Financial Services Ltd | Financial services | 2023 |
| Stockton Heath Car Sales Limited | Wholesale & retail | 2005 |
| Stockton Heath Conveyancing Limited | Professional & scientific | 1984 |
| Stockton Heath Electrical Limited | Construction | 2007 |
| Stockton Heath Gallery Ltd | Wholesale & retail | 2025 |
| Stockton Heath Heating Limited | Construction | 2003 |
| Stockton Heath Law Limited | Financial services | 2023 |
| Stockton Heath Medical LLP | | 2011 |
| Stockton Heath Project Management Ltd | Construction | 2013 |
| Stocktonheath Smile Centre Ltd | Health & social care | 2025 |
| Stocktons Homes Limited | Real estate | 2016 |
| Stoken Healthcare Ltd | Health & social care | 2024 |
| Stomm Ltd | Information & communication | 2011 |
| Stone and Anvil Ltd | Wholesale & retail | 2025 |
| Stone and Nash Limited | Administrative & support | 2012 |
| Stone AV Limited | Administrative & support | 2019 |
| Stone Central (NW) EOT Ltd | Financial services | 2024 |
| Stone Central (NW) Ltd | Manufacturing | 2002 |
| Stone Central Limited | Extraterritorial | 2010 |
| Stone Commercial Services Ltd | Administrative & support | 2025 |
| Stone Cross Mortgages Ltd | Financial services | 2019 |
| Stone FEN Engineering Services Ltd | Professional & scientific | 2024 |
| Stone Products (UK) Limited | Wholesale & retail | 1993 |
| Stone Properties (NW) Ltd | Real estate | 2020 |
| Stone Property Rentals Ltd | Real estate | 2023 |
| Stone-Cross Estate Agents Limited | Real estate | 2011 |
| Stonebridge FM Consulting Ltd | Professional & scientific | 2020 |
| Stonecross Construction Limited | Wholesale & retail | 1987 |
| Stonedrift Courier Ltd | Transport & logistics | 2026 |
| Stonekeep Solutions Limited | Administrative & support | 2016 |
| Stoneraptor Construction Ltd | Construction | 2022 |
| Stoneys Scooter Shack Ltd | Wholesale & retail | 2025 |
| Storm Resources Ltd | Professional & scientific | 2021 |
| Storm Vehicle Transport Ltd | Transport & logistics | 2024 |
| STORMBRINGER30 Limited | Administrative & support | 2016 |
| Stormchute Ltd | Information & communication | 2019 |
| Stormgazer Holdings Ltd | Financial services | 2023 |
| Stormgazer Properties Ltd | Real estate | 2023 |
| Story Stitchers CIC | Arts & recreation | 2022 |
| Stotts Plumbing & Heating Ltd | Construction | 2018 |
| Stoves Group Ltd | Financial services | 1989 |
| Stoyanov Limited | Professional & scientific | 2025 |
| Straight Aero Engineering Limited | Administrative & support | 2014 |
| Straightforward Orthotic Solutions Ltd | Health & social care | 2023 |
| Stramx Limited | Wholesale & retail | 2026 |
| Strata Consultancy Limited | Professional & scientific | 2017 |
| Stratasolve Ltd | Mining & quarrying | 2006 |
| Strategic Natural Resources PLC | Mining & quarrying | 2004 |
| Strategic Operational Strategies Limited | Manufacturing | 2022 |
| Strategic Sales Operations Ltd | Professional & scientific | 2019 |
| Strategic Send Solutions Limited | Professional & scientific | 2022 |
| Strategic Structural Design Limited | Administrative & support | 2010 |
| Strategy One Investments Ltd | Real estate | 2022 |
| Strategy Return Ltd | Professional & scientific | 2017 |
| Stratton Finance Group Limited | Wholesale & retail | 2025 |
| Stratus Software Ltd | Information & communication | 2022 |
| Stratusbridge Limited | Administrative & support | 2026 |
| Strawberry Elvis Ltd | Other services | 2023 |
| Strawberry Software Solutions Limited | Information & communication | 2017 |
| Stream Sensing Ltd | Manufacturing | 2020 |
| Streamline Drone Solutions Ltd | Information & communication | 2021 |
| Streamline Group Solutions Ltd | Administrative & support | 2021 |
| Streamline Property Solutions Ltd | Real estate | 2024 |
| Streamline Site Solutions Ltd | Administrative & support | 2020 |
| Streamlineit Ltd | Administrative & support | 2025 |