| Sundance Minds Ltd | Education | 2026 |
| Suneva Imaging Ltd | Health & social care | 2024 |
| Sunflower Solutions Ltd | Administrative & support | 2008 |
| Sunlea Properties Limited | Real estate | 2023 |
| Sunniside Software Limited | Other services | 2018 |
| Sunnybrow Investments Limited | Real estate | 2022 |
| Sunnywood (Tottington) Limited | Administrative & support | 2011 |
| Sunray Consultancy Limited | Administrative & support | 2023 |
| Sunridge Upholstery Limited | Manufacturing | 2004 |
| Sunrise Harvest Foods Ltd | Hospitality | 2026 |
| Sunrize Health Care Ltd | Administrative & support | 2019 |
| Sunrize Properties Ltd | Real estate | 2022 |
| SUP Services Repair Ltd | Administrative & support | 2023 |
| Supa Products Ltd | Wholesale & retail | 2022 |
| Super BIM Ltd | Administrative & support | 2025 |
| Super Healthy Homes Limited | Wholesale & retail | 2023 |
| Super Red Takeaway Ltd | Hospitality | 2024 |
| Supercatski Industries Limited | Administrative & support | 2022 |
| Supercups Vending Limited | Other services | 1976 |
| Superglide Stairlifts Ltd | Manufacturing | 2009 |
| Superior Art Flooring Ltd | Construction | 2017 |
| Superior Eateries Limited | Hospitality | 2014 |
| Superiorlandscapes.Ne.Nw Limited | Administrative & support | 2021 |
| Supersoniq Ltd | Wholesale & retail | 2023 |
| Superstar PAS Ltd | Administrative & support | 2017 |
| Superstars Bell Tent Hire Limited | Other services | 2022 |
| Superstars Holiday Club Limited | Health & social care | 2013 |
| Supervisor Services Ltd | Construction | 2016 |
| Supplement & Nutrition LAB Limited | Wholesale & retail | 2024 |
| Suppli Homes Ltd | Real estate | 2026 |
| Supplier Efficiency Limited | Information & communication | 2025 |
| Support Learning Tuition Ltd | Education | 2020 |
| Supporting Children Ltd | Education | 2021 |
| Supram Consultancy Services Ltd | Information & communication | 2012 |
| Supreme Consults Limited | Professional & scientific | 2017 |
| Supreme Valeting Warrington Ltd | Administrative & support | 2022 |
| Surai Limited | Professional & scientific | 2015 |
| Sure Business Consultancy Ltd | Professional & scientific | 2015 |
| Sure MED Limited | Manufacturing | 2009 |
| Sure S Solutions Ltd | Financial services | 2023 |
| Surefold Limited | Manufacturing | 2013 |
| Surekha Limited | Information & communication | 2022 |
| Suresite Management Ltd | Professional & scientific | 2025 |
| Surf Chec Ltd | Administrative & support | 2025 |
| Surface Design Limited | Professional & scientific | 2016 |
| Surface Solutions Limited | Construction | 2024 |
| Surfdoll Limited | Households | 1987 |
| Surge ADS Limited | Professional & scientific | 2026 |
| Surge LAB Ltd | Professional & scientific | 2025 |
| Surgident UK Ltd | Health & social care | 2010 |
| Surita Ltd | Administrative & support | 2023 |
| Surtr Assets Ltd | Administrative & support | 2017 |
| Surveillance Systems Ltd | Information & communication | 2019 |
| Surveying & Mapping Services Limited | Professional & scientific | 2016 |
| Surveyorsnorthwest Limited | Professional & scientific | 2023 |
| Survit Ltd | Administrative & support | 2022 |
| Susan Arnold Interiors Ltd | Professional & scientific | 2011 |
| Susan Ellison Limited | Professional & scientific | 2011 |
| Susan Petley Limited | Health & social care | 2014 |
| Sustainable Civils Ltd | Construction | 2025 |
| Sustainable Energy & Fuels Group (Holdings) Ltd | Professional & scientific | 2022 |
| Sustainable Energy & Fuels Group Ltd | Professional & scientific | 2013 |
| Sustainable Foot Forward Limited | Administrative & support | 2023 |
| Sustainable Friendly Fuels Limited | Water & waste | 2021 |
| Sustainable Heat & Power Group Limited | Energy | 2021 |
| Sutch Properties Limited | Real estate | 2024 |
| Sutherland Cabinets Limited | Manufacturing | 2002 |
| Suttieside Battery Limited | Financial services | 2020 |
| Suttieside Energy Limited | Financial services | 2020 |
| Sutton Commercial Management Ltd | Administrative & support | 2010 |
| Sutton Hairdressing Limited | Other services | 2011 |
| Sutton Healthcare Ltd | Administrative & support | 2021 |
| Sutton Images Ltd | Professional & scientific | 2018 |
| Sutton Motorsport Images Ltd | Professional & scientific | 2018 |
| Sutton Twentytwo Ltd | Wholesale & retail | 2023 |
| Suttons Wharf Limited | Information & communication | 2014 |
| Suzoo Ltd | Information & communication | 2017 |
| Suzy Crook Consulting Ltd | Professional & scientific | 2026 |
| SV Consultants Limited | Professional & scientific | 2014 |
| SV Group Limited | Other services | 2023 |
| SVG Rentals Ltd | Real estate | 2021 |
| SVR Ventures Limited | Administrative & support | 2021 |
| SW Drainage Surveys Limited | Administrative & support | 2024 |
| SW Driving School Ltd | Education | 2018 |
| SW Labs Ltd | Information & communication | 2018 |
| SW Richardson Projects Limited | Professional & scientific | 2022 |
| SW2 Consulting Limited | Information & communication | 2023 |
| Swaft SAP Services Ltd | Professional & scientific | 2024 |
| Swan Property Solutions Ltd | Real estate | 2020 |
| Swasivious Systems Ltd | Information & communication | 2009 |
| Sway the MOB Ltd | Professional & scientific | 2024 |
| Sweeney Digital Consultancy Limited | Information & communication | 2021 |
| Sweers Ltd | Professional & scientific | 2023 |
| Sweet Colours Ltd | Manufacturing | 2014 |
| Swehap Limited | Information & communication | 2010 |
| SWF Logistics Solutions Limited | Professional & scientific | 2024 |
| SWH Legal Services Limited | Administrative & support | 2015 |
| Swift and Clean Ltd | Administrative & support | 2023 |
| Swift Property Investments Limited | Real estate | 2000 |
| Swift Rail Services Ltd | Professional & scientific | 2024 |