| East Eleven Taunton Limited | Households | 2008 |
| East Kent Veterinary Referrals Ltd | Professional & scientific | 2024 |
| East Midlands Earthworks Ltd | Extraterritorial | 2024 |
| East Oxford Primary Health Collective Limited | Health & social care | 2021 |
| East Quay Properties Limited | Real estate | 2014 |
| East Reach Barber Ltd | Other services | 2026 |
| East to West Media Ltd | Professional & scientific | 2023 |
| Eastbury Estates (1955) Limited | Agriculture & fishing | 1955 |
| Eastcombe Farm Management Company Ltd | Households | 2021 |
| Easter House Management Company (Tiverton) Limited | Households | 1977 |
| Easterdown Ltd | Manufacturing | 1995 |
| Easterlands Estate Limited | Information & communication | 2019 |
| Eastern Blue Limited | Administrative & support | 2013 |
| Eastgate Euro Mini Market Ltd | Wholesale & retail | 2024 |
| Eastgate Gardens (Taunton) Limited | Households | 1989 |
| Eastgate MGT CIC | Households | 2019 |
| Eastry Veterinary Centre Limited | Professional & scientific | 2019 |
| Eastwick Farm Management Company Limited | Real estate | 2009 |
| Eastwood Park Holdings Ltd | Financial services | 2025 |
| Eastwood Park Limited | Hospitality | 2002 |
| Eastwood Park Training Centre Ltd | Financial services | 2025 |
| Eastwood Park Training Ltd | Education | 2025 |
| Easy 2 ASK Ltd | Professional & scientific | 2014 |
| Easy 2 DO Ltd | Professional & scientific | 2019 |
| Easy 2 Ltd | Professional & scientific | 2014 |
| Easy Cabs Taunton Ltd | Transport & logistics | 2025 |
| Easy Fleet Logistics Ltd | Wholesale & retail | 2017 |
| Easy Roll Industrial Doors Ltd | Construction | 2021 |
| Easy Tiger Takeaway Ltd | Hospitality | 2026 |
| EAT Afrique Ltd | Manufacturing | 2026 |
| EAT AI Limited | Information & communication | 2024 |
| EAT the Land Ltd | Information & communication | 2025 |
| EAT Write Limited | Administrative & support | 2004 |
| EB Bennett Ltd | Financial services | 2025 |
| EB Carpentry and Building Maintenance Limited | Construction | 2014 |
| Eben Forbes Ltd | Wholesale & retail | 2000 |
| EBF LLP | | 2009 |
| EBG Investments Ltd | Financial services | 2023 |
| Ebikienmo Trish Limited | Health & social care | 2025 |
| EC (South West) Limited | Professional & scientific | 2024 |
| Eccles SOT Limited | Wholesale & retail | 1997 |
| ECH Investments Ltd | Financial services | 2022 |
| Eclipse Electrical Ltd | Construction | 2019 |
| Eclipse Elite Twirlers Ltd | Arts & recreation | 2025 |
| Eclipse Event Solutions Ltd | Administrative & support | 2016 |
| Eclipse Event Specialists Limited | Administrative & support | 2000 |
| Eclipse Lounge Limited | Extraterritorial | 2008 |
| Eclipse Sports Events Ltd | Administrative & support | 2026 |
| ECM Southwest Ltd | Education | 2016 |
| Eco Diagnostics Limited | Professional & scientific | 2000 |
| Eco Energy Plumbing and Renewables Limited | Construction | 2024 |
| Eco NRG Group Limited | Construction | 2022 |
| Eco NRG Installations Ltd | Extraterritorial | 2015 |
| Eco NRG Operations and Maintenance Ltd | Extraterritorial | 2015 |
| Eco Party BAG Limited | Wholesale & retail | 2019 |
| Ecobuild DBR Ltd | Construction | 2026 |
| Ecoheat Plumbing and Renewables Limited | Construction | 2024 |
| Ecomledger Ltd | Information & communication | 2021 |
| Ecommerce 23 Ltd | Information & communication | 2022 |
| Ecountability Ltd | Information & communication | 2011 |
| ECS Bridgwater Limited | Administrative & support | 2023 |
| Ectometor Ltd | Administrative & support | 1988 |
| ED Simmons PIC Ltd | Agriculture & fishing | 2018 |
| Edd’S Collective Limited | Health & social care | 2019 |
| Eden Wedding Florist Ltd | Wholesale & retail | 2026 |
| EDEN4FLOWERS.CO.UK Ltd | Wholesale & retail | 2003 |
| Edge Yard Developments Limited | Real estate | 2020 |
| EDH Logistics Ltd | Transport & logistics | 2024 |
| Edlington Limited | Professional & scientific | 1996 |
| Edmund Bailhache Limited | Real estate | 2007 |
| Edrod Retail Ltd | Wholesale & retail | 2022 |
| EDU Tech Labs Ltd | Information & communication | 2025 |
| Edward Bishop Limited | Professional & scientific | 2022 |
| Edward Cleaning Services Ltd | Transport & logistics | 2012 |
| Edward House (Taunton) Management Limited | Households | 2001 |
| Edward James Caravans Limited | Wholesale & retail | 2020 |
| Edward James Lettings Ltd | Real estate | 2021 |
| Eemu Ltd | Construction | 2018 |
| Efcho Investment Limited | Health & social care | 2012 |
| Effectually Limited | Professional & scientific | 2008 |
| Ehla Properties Limited | Real estate | 2013 |
| Eight Eights Limited | Professional & scientific | 2003 |
| Eight Second Network Ltd | Professional & scientific | 2025 |
| Ekim Consulting Limited | Administrative & support | 2016 |
| Ekoknitwear Limited | Manufacturing | 2025 |
| Ekos Kitchens & Bathrooms Ltd | Professional & scientific | 2025 |
| EL Marcel Ltd | Wholesale & retail | 2022 |
| EL Olivar Limited | Real estate | 2011 |
| EL Tesoro DE LOS Abuelos Ltd | Real estate | 2015 |
| El-Nashar Dental Care Limited | Health & social care | 2006 |
| Elara Holdings Limited | Professional & scientific | 2016 |
| Elbo Ltd | Financial services | 2025 |
| Elderfield Developments Limited | Construction | 2007 |
| Electromec Services Limited | Professional & scientific | 2007 |
| Elenbaas Vastgoed LLP | | 2018 |
| Elenium Health Ltd | Health & social care | 2012 |
| Elesab E Ltd | Wholesale & retail | 2025 |
| Elevate & Enclose Ltd | Construction | 2025 |
| Elevate Business Performance Limited | Transport & logistics | 2017 |
| Elevate Land Solutions Limited | Professional & scientific | 2026 |