| Stafford Muslim Community Centre | Other services | 2000 |
| Stafford Nails & Beauty Limited | Other services | 2019 |
| Stafford Osteopathic Clinic Limited | Health & social care | 2015 |
| Stafford Padel Ltd | Construction | 2025 |
| Stafford Pallet Warehouse Ltd | Wholesale & retail | 2026 |
| Stafford Pizza Limited | Hospitality | 2019 |
| Stafford Plant Hire Limited | Construction | 2021 |
| Stafford Pride CIC | Arts & recreation | 2023 |
| Stafford Property Services Limited | Construction | 2019 |
| Stafford Radio Broadcasting Limited | Information & communication | 2013 |
| Stafford Rangers Football Club Limited | Arts & recreation | 1920 |
| Stafford Removals Ltd | Transport & logistics | 2022 |
| Stafford Retro and IT Services Limited | Wholesale & retail | 2024 |
| Stafford Roofing Contractors Ltd | Information & communication | 2026 |
| Stafford Rugby Limited | Arts & recreation | 2015 |
| Stafford Rugby Union Football Club Limited | Arts & recreation | 2010 |
| Stafford School of Dance Ltd | Education | 2021 |
| Stafford Showground Limited | Real estate | 1995 |
| Stafford Soccer School Ltd. | Education | 2016 |
| Stafford Sound Labs Limited | Extraterritorial | 2023 |
| Stafford Sports and Performance Academy Limited | Arts & recreation | 2014 |
| Stafford Storage Limited | Real estate | 2017 |
| Stafford Swimming Academy Limited | Extraterritorial | 2017 |
| Stafford Tiles and Flooring Solutions Limited | Construction | 2009 |
| Stafford Towbars Limited | Manufacturing | 2015 |
| Stafford Town Barber Ltd | Other services | 2021 |
| Stafford Town Football Foundation | Arts & recreation | 2007 |
| Stafford Truck & BUS Ltd | Administrative & support | 2008 |
| Stafford Upvc Windows Limited | Construction | 1990 |
| Stafford Van Sales Ltd | Wholesale & retail | 2018 |
| Stafford Vehicle Sales Ltd | Wholesale & retail | 2022 |
| Stafford YMP Ltd | Education | 2019 |
| Staffordshire & Birmingham Agricultural Society | Other services | 1998 |
| Staffordshire 6 Ltd | Real estate | 2018 |
| Staffordshire Bars Limited | Hospitality | 2024 |
| Staffordshire Bricklaying and Plastering Ltd | Construction | 2013 |
| Staffordshire Building Services Limited | Construction | 2024 |
| Staffordshire Community Hub CIC | Hospitality | 2015 |
| Staffordshire Construction Training Limited | Administrative & support | 2018 |
| Staffordshire Council of Voluntary Youth Services | Health & social care | 2009 |
| Staffordshire Cricket Limited | Education | 2010 |
| Staffordshire Cultural Events C.I.C. | Arts & recreation | 2019 |
| Staffordshire Digital Ltd | Information & communication | 2017 |
| Staffordshire Ecological Services Limited | Professional & scientific | 2008 |
| Staffordshire Electrical Installations Ltd | Construction | 2024 |
| Staffordshire FA Facilities Limited | Arts & recreation | 2025 |
| Staffordshire Family Law Solicitors Limited | Professional & scientific | 2012 |
| Staffordshire FD Solutions Limited | Professional & scientific | 2015 |
| Staffordshire Fencing Ltd | Administrative & support | 2011 |
| Staffordshire Firewood Logs Ltd | Wholesale & retail | 2025 |
| Staffordshire Garden Landscaping Ltd | Water & waste | 2020 |
| Staffordshire Gardens and Parks Trust Company Limited | Other services | 1992 |
| Staffordshire Gliding Club Limited | Arts & recreation | 1987 |
| Staffordshire Healthcare Staffing Ltd | Administrative & support | 2013 |
| Staffordshire Heating Ltd | Construction | 2009 |
| Staffordshire Inventories Ltd | Real estate | 2012 |
| Staffordshire Motor Services Ltd | Wholesale & retail | 2022 |
| Staffordshire Motorhome Hire Limited | Administrative & support | 2024 |
| Staffordshire Narrow Gauge Railway Limited | Transport & logistics | 1987 |
| Staffordshire Oak Services Ltd | Construction | 2015 |
| Staffordshire Pest Control Ltd | Administrative & support | 2007 |
| Staffordshire Physio Pain Relief and Sports Injury Clinic Limited | Health & social care | 2024 |
| Staffordshire Plastics Limited | Wholesale & retail | 1980 |
| Staffordshire Print Limited | Manufacturing | 2013 |
| Staffordshire PUB Company Limited | Hospitality | 2003 |
| Staffordshire Radford (Property and Investments) Ltd | Financial services | 2020 |
| Staffordshire Roofing Limited | Construction | 2024 |
| Staffordshire Scaffolding Limited | Construction | 2025 |
| Staffordshire Skin Doctor Ltd | Health & social care | 2021 |
| Staffordshire Smiles Ltd | Health & social care | 2023 |
| Staffordshire South West Citizens Advice Bureau | Other services | 2012 |
| Staffordshire Specialist Cars Ltd | Wholesale & retail | 2021 |
| Staffordshire Stoves Limited | Construction | 2012 |
| Staffordshire Technical Services Limited | Professional & scientific | 2016 |
| Staffordshire Traditional Meats & Bakehouse Ltd | Wholesale & retail | 2021 |
| Staffordshire Training Services Limited | Professional & scientific | 2021 |
| Staffordshire Wildlife Trading Limited | Wholesale & retail | 1997 |
| Staffordshire Wildlife Trust Limited | Other services | 1969 |
| Staffordshire Worms Limited | Wholesale & retail | 2026 |
| Staffprop Ltd | Households | 2025 |
| Staffs Group Ltd | Construction | 2010 |
| Staffs Lofts Ltd | Construction | 2024 |
| Staffs Powder Coating & Blasting Limited | Manufacturing | 2023 |
| Staffs Power Cables Limited | Construction | 2006 |
| Staffs Scenic Solutions Ltd | Arts & recreation | 2025 |
| Staffs Security Systems Limited | Manufacturing | 2017 |
| Staffsfd Limited | Professional & scientific | 2022 |
| Staffy Vape Limited | Wholesale & retail | 2019 |
| Stag Engineering Ltd | Professional & scientific | 2023 |
| Stai Europe Limited | Wholesale & retail | 2021 |
| Stalium Ltd | Professional & scientific | 2020 |
| Stan Robinson (Distribution) Limited | Transport & logistics | 1987 |
| Stan Robinson (Stafford) Limited | Transport & logistics | 1991 |
| Stan Robinson Group Limited | Transport & logistics | 1975 |
| Standon Hall Events Limited | Other services | 2019 |
| Stanley Sports Limited | Wholesale & retail | 2021 |
| Staple Fire Ltd | Administrative & support | 2024 |
| Star Espresso Machines Limited | Manufacturing | 2006 |
| Star Faisal Services Ltd | Health & social care | 2023 |
| Star Global Import and Export Co., Ltd. | Wholesale & retail | 2024 |