| Elbury Homes Limited | Real estate | 2018 |
| Elecpulse UK Ltd | Wholesale & retail | 2025 |
| Electrical & Media Solutions Ltd | Construction | 2024 |
| Electricstone Limited | Information & communication | 2002 |
| Electro Games Limited | Information & communication | 2025 |
| Elegant Narcissus Ltd | Information & communication | 2025 |
| Elegante Ltd | Other services | 2025 |
| Element Brand Group Limited | Financial services | 2022 |
| Element Brand Group of Companies Limited | Construction | 2016 |
| Element Colors Technology Limited | Information & communication | 2020 |
| Elemental Shift Ltd | Information & communication | 2020 |
| Elephant in the Room Productions Ltd | Arts & recreation | 2025 |
| Elesky Ltd | Wholesale & retail | 2025 |
| Eleusis Capital LP | | 2022 |
| Elevated Lifestyle Limited | Wholesale & retail | 2024 |
| Eleven Prosperity Limited | Real estate | 2026 |
| ELF Software Limited | Information & communication | 2004 |
| Elgin Caine Ltd | Professional & scientific | 2021 |
| Elgin Comet Ltd | Hospitality | 2024 |
| Elite Fibre Communications Limited | Information & communication | 2020 |
| Elite Groundworks & Construction Contractors Ltd | Construction | 2007 |
| Elite Motoring Associates Ltd | Education | 2022 |
| Elite Training (Stafford) Limited | Education | 2019 |
| Elitecraft Ltd | Construction | 2025 |
| Elixir Hair and Makeup Limited | Other services | 2018 |
| Elizavic Construction Limited | Professional & scientific | 2025 |
| Eljake Ltd | Real estate | 2021 |
| ELK Consortium Limited | Wholesale & retail | 2026 |
| Ella Melrose Ltd | Professional & scientific | 2020 |
| Elliot Alexander Holdings Limited | Health & social care | 2020 |
| Elliott Lion Limited | Arts & recreation | 2017 |
| Ellis Limited | Wholesale & retail | 2026 |
| Ellison Wealth Management Ltd | Financial services | 2022 |
| ELM People Limited | Administrative & support | 2020 |
| Elmak Electrical Co., Ltd | Extraterritorial | 2016 |
| Elmhurst Holdings Limited | Real estate | 2016 |
| Elmore Court (Management) Limited | Real estate | 2026 |
| Elms Farm (Albrighton) Limited | Agriculture & fishing | 1963 |
| Elney Group Ltd | Professional & scientific | 2025 |
| Elsdon Guitar Tech Limited | Arts & recreation | 2025 |
| Elucidian Limited | Information & communication | 2025 |
| Elwyn Infotech Ltd | Information & communication | 2017 |
| Elysian Upholstery Limited | Wholesale & retail | 2018 |
| Emac Management Services Ltd | Manufacturing | 2017 |
| Emad Import and Export Co., Ltd | Wholesale & retail | 2024 |
| Emanuel Transport 24 Ltd | Transport & logistics | 2024 |
| Emari Holdings Ltd | Financial services | 2022 |
| Emas Electric Ltd | Administrative & support | 2015 |
| EMC Hycal Limited | Manufacturing | 2007 |
| Emenar Logistics Ltd | Transport & logistics | 2023 |
| Emerald Rose Property Group Ltd | Real estate | 2025 |
| Emerged HK Ltd | Manufacturing | 2018 |
| Emeritus Property Limited | Real estate | 2022 |
| Emma Louise Elliott Ltd | Administrative & support | 2019 |
| Empire Collectibles Ltd | Wholesale & retail | 2026 |
| Empire Motor Service Ltd | Wholesale & retail | 2024 |
| Ems-Chemie (UK) Ltd | Wholesale & retail | 1956 |
| Emsales Ltd | Extraterritorial | 2024 |
| EMU Consultancy Limited | Professional & scientific | 2014 |
| Enabling Activities Limited | Other services | 2018 |
| Enabling Technology Limited | Administrative & support | 2011 |
| Enayar Investments Limited | Real estate | 2025 |
| Enbee Decor Ltd | Construction | 2026 |
| Enerficiency Ltd | Professional & scientific | 2016 |
| Energiesprong UK Limited | Professional & scientific | 2015 |
| Energy Saving Home Improvements Ltd | Construction | 2020 |
| Energy Saving Windows Stafford Limited | Manufacturing | 2012 |
| Energy Test Solutions Ltd | Construction | 2019 |
| Enerzar Ltd | Professional & scientific | 2020 |
| Engage Building Consultancy Limited | Construction | 2026 |
| Engage to Perform Ltd | Professional & scientific | 2013 |
| Engaging Communities Solutions CIC | Professional & scientific | 2012 |
| Engineering & Canal Services of Great Haywood Limited | Manufacturing | 1996 |
| Engineering Direct Limited | Administrative & support | 2020 |
| Engineering Direct Recruitment UK Limited | Administrative & support | 2026 |
| Engineering Services Plastics Limited | Professional & scientific | 2013 |
| Enjoy Property Ventures Ltd | Real estate | 2026 |
| Enjoy Sales Holdings Limited | Professional & scientific | 2018 |
| Enjoy-Sales Ltd | Professional & scientific | 2002 |
| Enjoying Creativity Outdoors CIC | Education | 2023 |
| Enlighten AV Ltd | Administrative & support | 2024 |
| Enovert Energy Limited | Energy | 1995 |
| Enovert Limited | Extraterritorial | 2017 |
| Enovert North Limited | Water & waste | 1992 |
| Enovert South Limited | Water & waste | 1991 |
| Enstatic Properties Ltd | Real estate | 2019 |
| Enterprise Roofing (Stafford) Limited | Construction | 2016 |
| Entrust Support Services Limited | Financial services | 2002 |
| Environmental Monitoring and Control Limited | Manufacturing | 1993 |
| Enviroprint Packaging Limited | Professional & scientific | 2019 |
| Envy Hair and Skin Clinic Ltd | Other services | 2024 |
| EP Services Penkridge Limited | Construction | 2007 |
| Epds Limited | Professional & scientific | 2011 |
| Epitome Accommodation Limited | Hospitality | 2022 |
| Epoch Origin Mediatech Ltd | Wholesale & retail | 2025 |
| EPX Limited | Information & communication | 2005 |
| EPX Saas Limited | Information & communication | 2019 |
| EQUIP4WORK Ltd | Wholesale & retail | 2004 |
| Equitus Group Ltd | Other services | 2021 |
| Equiverify Limited | Administrative & support | 2026 |