| CXW Co., Ltd | Wholesale & retail | 2023 |
| Cyffel MOR Developments Limited | Real estate | 2016 |
| Cynd Residential Homes Ltd | Health & social care | 2025 |
| CYP Care in Mind Ltd | Health & social care | 2022 |
| D & a Clinical Coding Consultancy Limited | Professional & scientific | 2006 |
| D & B Roofing & Building Ltd | Construction | 2024 |
| D & K Property Holdings Ltd | Real estate | 2020 |
| D & K PUB Management Ltd | Hospitality | 2025 |
| D C Access Specialists Ltd | Administrative & support | 2014 |
| D H Structures Limited | Manufacturing | 1997 |
| D H Taxis Ltd | Transport & logistics | 2014 |
| D J B Interiors Ltd | Construction | 2014 |
| D K Services (Stafford) Ltd | Construction | 2012 |
| D L Tams Limited | Construction | 2007 |
| D M Fisher Roofing Ltd | Construction | 2024 |
| D M T Sound Limited | Information & communication | 2011 |
| D N Wray Ltd | Construction | 2018 |
| D R & C E Williams Ltd | Agriculture & fishing | 2022 |
| D R Cantrill Limited | Manufacturing | 2002 |
| D R M Technic Holdings Ltd | Financial services | 2022 |
| D R M Technic Ltd | Wholesale & retail | 2009 |
| D&E Enterprises Ltd | Hospitality | 2017 |
| D&Q Properties Ltd | Real estate | 2024 |
| D&S Governance Services Ltd | Professional & scientific | 2025 |
| D. Beardsmore Limited | Construction | 2010 |
| D. M. Secure Storage Limited | Administrative & support | 2011 |
| D. Norris Properties Ltd | Real estate | 2024 |
| D.A.O Engineering Ltd | Administrative & support | 2007 |
| D.L.Murray Properties Limited | Real estate | 1959 |
| D.Rysiak GAS Service Ltd | Construction | 2023 |
| D16RR Solutions Limited | Information & communication | 2010 |
| D3I Limited | Information & communication | 2010 |
| DA Share Ltd | Hospitality | 2025 |
| Daccaa Ltd | Information & communication | 2023 |
| Daechyeong Press Ltd | Wholesale & retail | 2025 |
| DAH Carpenters Ltd | Construction | 2018 |
| Daisy Nails 88 Ltd | Other services | 2025 |
| Dalas Chicken Star Limited | Hospitality | 2019 |
| Dalgarno Limited | Wholesale & retail | 2003 |
| Damss Ltd | Real estate | 2023 |
| Damxay Trading Ltd | Wholesale & retail | 2025 |
| DAN Jolley Flooring Ltd | Construction | 2017 |
| Dance Fitness Stafford Ltd | Arts & recreation | 2026 |
| Dance Fusion Community Dance School Limited | Arts & recreation | 2012 |
| Danci World Group Co., Ltd | Wholesale & retail | 2025 |
| Dandy Projects Limited | Construction | 2015 |
| Daniel Jones (Gnosall) Ltd | Construction | 2020 |
| Daniel Langley Design Limited | Professional & scientific | 2021 |
| Daniel Mielke Ltd | Professional & scientific | 2022 |
| Daniel Simon’S Ltd | Hospitality | 2026 |
| Dapper & Boss Barbers Ltd | Other services | 2023 |
| Dark Laboratories Ltd | Information & communication | 2023 |
| Darling Tech Ltd | Information & communication | 2026 |
| Darnbrough Football Consultancy Ltd | Professional & scientific | 2025 |
| Darren Fisher Roofing Contractors Ltd | Construction | 2013 |
| Darrexpol Ltd | Manufacturing | 2019 |
| Darsh Ltd | Professional & scientific | 2022 |
| Dash and Dash Limited | Health & social care | 2018 |
| Data Literate Ltd | Professional & scientific | 2019 |
| Data Services (GB) Limited | Other services | 2007 |
| Dataconnex Ltd | Information & communication | 2022 |
| Dataflexnet Ltd | Information & communication | 1996 |
| Dataip Limited | Information & communication | 2002 |
| Datapoint Research Ltd. | Professional & scientific | 2004 |
| Dataworkshop Limited | Information & communication | 2022 |
| Datgogo Technology Ltd | Wholesale & retail | 2015 |
| Dave's Right Price Carpet & Flooring Limited | Wholesale & retail | 2018 |
| David Arthur (Lichfield) Limited | Professional & scientific | 2010 |
| David Charlton Consultancy Services Limited | Information & communication | 2023 |
| David Eaton Tractors Limited | Wholesale & retail | 1999 |
| David Gough Investments LLP | | 2011 |
| David James Developments Limited | Construction | 2013 |
| David Lean Films Ltd | Arts & recreation | 1997 |
| David Manning Consulting Limited | Professional & scientific | 2022 |
| David Rushton Machinery Ltd | Wholesale & retail | 2003 |
| Davies GAS Services Ltd | Construction | 2025 |
| Davonix Limited | Information & communication | 2026 |
| Davros Consultancy Limited | Professional & scientific | 2018 |
| Davyty Limited | Wholesale & retail | 2025 |
| Dawkes & Co Limited | Construction | 2001 |
| Dawntop Holding Limited | Extraterritorial | 2011 |
| Dawson Family Trading Ltd | Administrative & support | 2022 |
| Daxi International Co., Ltd | Manufacturing | 2025 |
| Day and Knight Limited | Construction | 2015 |
| Daystate Limited | Manufacturing | 1978 |
| DBL Jetwash Limited | Administrative & support | 2021 |
| DBL Snag and Tint Limited | Construction | 2022 |
| DC Decorating Contractors Limited | Construction | 2016 |
| DC Planning Consultancy Limited | Administrative & support | 2016 |
| DC Universe Ltd | Information & communication | 2024 |
| DDD Property Developments Ltd | Construction | 2006 |
| Ddmandas Services Limited | Health & social care | 2024 |
| DE Burgo Go Go Ltd | Hospitality | 2015 |
| Deaconsfield Financial Planning Limited | Financial services | 2004 |
| Deaconsfield Property Limited | Real estate | 2019 |
| Deakin Creations Ltd | Manufacturing | 2021 |
| Dean Hassell Media Ltd | Administrative & support | 2024 |
| Dean Lunn Flooring Ltd | Construction | 2024 |
| Dean Statham Wealth Management LLP | | 2008 |
| Deane Contractors Limited | Agriculture & fishing | 2012 |