| Conveyassist Ltd | Administrative & support | 2020 |
| Convy Stores Limited | Wholesale & retail | 2023 |
| Coolexion Ltd | Wholesale & retail | 2022 |
| Coombs Property Management Limited | Real estate | 2019 |
| Cooner Medical Services LLP | | 2009 |
| Coopers Waste Management Services (Staffordshire) Limited | Water & waste | 2018 |
| Copart Co., Ltd | Manufacturing | 2022 |
| Coppenhall Mews Management Company Limited | Households | 2004 |
| Coppetts Road Limited | Construction | 2014 |
| Coppice Property Holdings Limited | Financial services | 2018 |
| Coral Print Ltd | Wholesale & retail | 2018 |
| Corbeau II Limited | Transport & logistics | 2025 |
| Cordial Property Ltd | Real estate | 2024 |
| Core and Cluster Ltd | Health & social care | 2025 |
| Core Solution Group UK Limited | Administrative & support | 2024 |
| Corgin Group Limited | Financial services | 2022 |
| Corgin Limited | Manufacturing | 2007 |
| Corman Limited | Manufacturing | 2003 |
| Corporate Apparel Ltd | Wholesale & retail | 2022 |
| Corridors Trading Co., Limited | Wholesale & retail | 2025 |
| Corrigan Hydraulic Services Ltd | Manufacturing | 2022 |
| Corundum Limited | Administrative & support | 1978 |
| CORUS360 Ltd | Information & communication | 2006 |
| Cosmedic Beauty Limited | Health & social care | 2016 |
| Cost Reduction Analysts Ltd | Other services | 2014 |
| Cosyhomeenergysolutions Ltd | Construction | 2019 |
| Cotes Heath Testing Centre Ltd | Wholesale & retail | 2019 |
| Cotes Solar Company Limited | Real estate | 2021 |
| Country Buckets and Blooms Ltd | Agriculture & fishing | 2026 |
| Countryside Training & Tree Management Ltd | Agriculture & fishing | 2003 |
| County Town Homes (Stafford) Limited | Construction | 2017 |
| Couture Leisure Limited | Hospitality | 2009 |
| Cove Daily Ltd | Wholesale & retail | 2025 |
| Coven Care Homes Holdings Ltd | Real estate | 2025 |
| Coven Care Homes Ltd | Health & social care | 2022 |
| Cowmeadow Electrical Ltd | Construction | 2023 |
| Cowshed Works Limited | Information & communication | 2016 |
| COX Farming Company | Agriculture & fishing | 2012 |
| Coymad Property Services Limited | Manufacturing | 2000 |
| CP Distribution Ltd | Wholesale & retail | 2026 |
| CP26 Commercial Limited | Manufacturing | 2026 |
| Cpap Solutions Limited | Wholesale & retail | 2011 |
| Cphtraining Leeds Ltd | Health & social care | 2020 |
| Cproeurope Ltd | Construction | 2022 |
| Craft-Tack-Stick Ltd. | Manufacturing | 2015 |
| Craig Eccleston Photographics Ltd | Other services | 2010 |
| Craig Pilsbury Building Services Ltd | Construction | 2016 |
| Cranford (18) Limited | Real estate | 2018 |
| Cranford Geotech Limited | Mining & quarrying | 2016 |
| Cranston Ventures Holdings Limited | Financial services | 2024 |
| Crave Cave Cafe Ltd | Manufacturing | 2024 |
| Crazy Driver Limited | Extraterritorial | 2015 |
| Crazy House Productions Limited | Information & communication | 2018 |
| Creative and Wellbeing Services Ltd | Health & social care | 2025 |
| Creative BEE Limited | Manufacturing | 2009 |
| Creative First Media Ltd | Manufacturing | 2020 |
| Creative Paper Ltd | Manufacturing | 2011 |
| Crescent Chocolates Ltd | Extraterritorial | 2024 |
| Crescent Estates (Property Consultants) Limited | Real estate | 2009 |
| Crescent Estates Holdings Limited | Financial services | 2022 |
| Crescent Health UK Limited | Health & social care | 2017 |
| Cress Security Company Limited | Administrative & support | 1984 |
| Creswell Rentals Limited | Real estate | 1994 |
| Cristi-S Drylining Ltd | Construction | 2022 |
| Critical Task Limited | Information & communication | 2015 |
| CRM Construction Group Limited | Construction | 2025 |
| Crochet Investments Ltd | Real estate | 2020 |
| Croes Blaidd Ltd | Hospitality | 2021 |
| Croft Architecture Limited | Professional & scientific | 2009 |
| Cross Products Software Ltd | Information & communication | 2010 |
| Crossbow Education Limited | Information & communication | 2005 |
| Crowder Construction Limited | Construction | 2013 |
| Crown Street Recycling Limited | Wholesale & retail | 2020 |
| Croxton Consultancy Limited | Professional & scientific | 2015 |
| CRS Supplies & Services Ltd | Wholesale & retail | 2017 |
| CRT Associates Limited | Information & communication | 2012 |
| CRT Sales and Service Ltd | Wholesale & retail | 2020 |
| Cruiseworld Limited | Administrative & support | 1987 |
| Crumpet Factory Limited | Real estate | 2017 |
| Crunch 360 Marketing Limited | Professional & scientific | 2020 |
| Crushing Digital Ltd | Information & communication | 2018 |
| Crynahs Limited | Wholesale & retail | 2025 |
| CSC Vision Limited | Extraterritorial | 2016 |
| CSP Investments Ltd | Real estate | 2026 |
| CTR Factory Ltd | Professional & scientific | 2025 |
| Ctrl-D Ltd | Arts & recreation | 2015 |
| Cuddia Ltd | Professional & scientific | 2012 |
| Cuero Rico Ltd | Wholesale & retail | 2026 |
| Culverwell IT Services Limited | Information & communication | 2015 |
| CUP of Green Ltd | Manufacturing | 2025 |
| Cupid Global Freight Group (UK) Limited | Transport & logistics | 2021 |
| Curated Social Club Limited | Hospitality | 2022 |
| Curlita Beauty Limited | Other services | 2019 |
| Curry Fusion Stafford Ltd | Hospitality | 2025 |
| Cuttlestones Limited | Wholesale & retail | 2007 |
| Cvjpic Limited | Professional & scientific | 2023 |
| Cwautomotive Ltd | Wholesale & retail | 2026 |
| Cwfi Holdings Ltd | Financial services | 2026 |
| CWM Property & Lettings Ltd | Real estate | 2021 |
| CWO (Eccleshall) Limited | Other services | 2019 |