| Clena Ltd | Wholesale & retail | 2018 |
| Cleon Digital Consulting Ltd | Professional & scientific | 2025 |
| CLH Distribution Ltd | Wholesale & retail | 2017 |
| Clickety Clack Ltd | Administrative & support | 2024 |
| Client First Solutions Limited | Information & communication | 2019 |
| Cliff's Ground Maintenance Ltd | Administrative & support | 2026 |
| Clinexia Limited | Health & social care | 2026 |
| Clinexus Ltd | Professional & scientific | 2025 |
| Clinica Skin Ltd | Other services | 2022 |
| Cliqto Ltd | Professional & scientific | 2011 |
| CLM Manufacturing Limited | Manufacturing | 2002 |
| Cloudelebox Ltd | Wholesale & retail | 2025 |
| CM Entertainment Services Ltd | Arts & recreation | 2024 |
| CM Recycling Services Ltd | Water & waste | 2024 |
| Cmfm Ltd | Professional & scientific | 2022 |
| CMH Transport (UK) Limited | Transport & logistics | 2003 |
| Cmtm International Limited | Wholesale & retail | 2025 |
| Cnnb Properties Limited | Real estate | 2014 |
| Coach and Horses Lubenham Limited | Hospitality | 2025 |
| COACH2COACH Limited | Professional & scientific | 2021 |
| Coalition Event Services Ltd | Administrative & support | 2011 |
| Coastal Financial Planning Limited | Professional & scientific | 2019 |
| Coatden Limited | Other services | 2022 |
| Cobstone Consulting Ltd | Information & communication | 2026 |
| Cock at Stowe TDB Ltd | Extraterritorial | 2022 |
| Coco Pads Ltd | Real estate | 2025 |
| Cocoa Creations Ltd | Manufacturing | 2019 |
| Codan Limited | Wholesale & retail | 1986 |
| Codebased Limited | Information & communication | 2022 |
| Coded Internet Limited | Information & communication | 2013 |
| Codeloom Ltd | Information & communication | 2024 |
| Codeweavers (Holdings) Limited | Financial services | 2015 |
| Codeweavers Information Services Limited | Information & communication | 2021 |
| Codeweavers Limited | Information & communication | 2000 |
| Codiak-Lima Ltd | Transport & logistics | 2022 |
| Cofer Group Company Limited | Manufacturing | 2022 |
| Coinbaby Limited | Information & communication | 2021 |
| Colcom Biotechnology Limited | Wholesale & retail | 2025 |
| Coldrush Ltd | Construction | 2024 |
| Cole Medical Limited | Public administration | 2023 |
| Coligo Consulting Limited | Administrative & support | 2011 |
| Colin Davenport Limited | Manufacturing | 1988 |
| Colin Rawles Resources Limited | Professional & scientific | 1997 |
| Collinsshongo Ltd | Health & social care | 2023 |
| Color Trading Co., Ltd | Extraterritorial | 2015 |
| Colourite Systems Limited | Manufacturing | 1989 |
| Coltkell Holdings Limited | Financial services | 2026 |
| Coltkell Limited | Real estate | 1980 |
| Colun Limited | Extraterritorial | 2020 |
| Colwich Estates Limited | Real estate | 2023 |
| Come Into Play Limited | Health & social care | 2011 |
| Commercial AID Training Ltd | Financial services | 2014 |
| Commercial ARB Training Ltd | Extraterritorial | 2014 |
| Commercial Arborists Ltd | Agriculture & fishing | 2014 |
| Commercial Lending Solutions Limited | Financial services | 2015 |
| Comms Cable Ltd | Information & communication | 2018 |
| Community Forest Services Ltd | Agriculture & fishing | 2018 |
| Community Foundation for Staffordshire and Shropshire | Administrative & support | 2001 |
| Community Foundation Mercia Ltd | Health & social care | 2026 |
| Community Foundation Midshires Ltd | Health & social care | 2025 |
| Community Foundation Three Counties Ltd | Health & social care | 2026 |
| Community Foundation Three Shires Ltd | Health & social care | 2026 |
| Community Foundation Two Counties Ltd | Health & social care | 2026 |
| Community Foundation Two Shires Ltd | Health & social care | 2026 |
| Community Transport Stafford & District | Transport & logistics | 2002 |
| Compact Cleaning Services Ltd | Administrative & support | 2012 |
| Companion Grove CIC | Health & social care | 2025 |
| Compareit Limited | Administrative & support | 2013 |
| Compass AZ Trading Co., Limited | Wholesale & retail | 2025 |
| Compass QMS Limited | Professional & scientific | 2023 |
| Competitive Tracking Limited | Administrative & support | 2003 |
| Complete Building, Joinery & Plastering Services Ltd | Construction | 2018 |
| Complete Care Plus Services Limited | Other services | 2009 |
| Complete Environmental Solutions Ltd | Professional & scientific | 2014 |
| Complete Framing Solutions Limited | Wholesale & retail | 2011 |
| Compo (UK) Microfertilizer Ltd | Mining & quarrying | 2024 |
| Compusys Limited | Professional & scientific | 1987 |
| Confident Growth Ltd | Wholesale & retail | 2024 |
| Conn Investments Limited | Administrative & support | 2025 |
| Connect Print Consultancy Ltd | Administrative & support | 2025 |
| CONNECT2PADEL Limited | Arts & recreation | 2024 |
| Connectly Technology Limited | Wholesale & retail | 2024 |
| Connexica Holdings Limited | Information & communication | 2006 |
| Connexica Limited | Information & communication | 2006 |
| Consilium Medex Ltd | Professional & scientific | 2019 |
| Conspicuous CBM Limited | Administrative & support | 2009 |
| Constant Sea Ltd | Wholesale & retail | 2024 |
| Construction Dispute Solutions (UK) Limited | Professional & scientific | 2013 |
| Construction Service Midlands Ltd | Construction | 2015 |
| Construkt (Built Environment Consultants) Limited | Professional & scientific | 2017 |
| Consumer Thoughts Limited | Information & communication | 2024 |
| Content Investments Limited | Financial services | 2023 |
| Content With Media Ltd | Information & communication | 2019 |
| Contractor 6918 Limited | Real estate | 2019 |
| Contrary Mary Ltd | Manufacturing | 2015 |
| Control Corrosion Limited | Professional & scientific | 2024 |
| Control Panel Products Ltd | Wholesale & retail | 2022 |
| Control-Bridge Group Limited | Information & communication | 2018 |
| Converge Technology Solutions Holdings UK Limited | Other services | 2022 |
| Converge Technology Solutions UK Limited | Other services | 2022 |