| Deans (Staffordshire) Limited | Professional & scientific | 2013 |
| Deans Recruitment Limited | Administrative & support | 2018 |
| Deans Wealth Management Limited | Financial services | 2008 |
| Deansbrook Limited | Water & waste | 2021 |
| Deep Projects Ltd | Information & communication | 2013 |
| Deepdale Limited | Hospitality | 1993 |
| Deepfield Markets Limited | Information & communication | 2014 |
| Deeptrex Ltd | Information & communication | 2025 |
| Deeqsiye Trading Company Ltd | Wholesale & retail | 2023 |
| Deer Group Limited | Information & communication | 2021 |
| Defencewatch Limited | Information & communication | 2011 |
| Deganwy Properties Limited | Real estate | 2020 |
| Degrees Better Limited | Construction | 2011 |
| Dehuan Trading Limited | Wholesale & retail | 2024 |
| Deisdaw Ltd | Information & communication | 2015 |
| Dell PM Limited | Manufacturing | 2005 |
| Demarco Co., Ltd | Wholesale & retail | 2023 |
| Deming Supply Chain Management Co., Ltd | Wholesale & retail | 2024 |
| Demonprint Limited | Wholesale & retail | 2006 |
| Denry's Delivery Service Limited | Wholesale & retail | 2018 |
| Densom Ltd. | Wholesale & retail | 2017 |
| Denstone Statues Ltd | Manufacturing | 2021 |
| Dentalis Ltd | Health & social care | 2019 |
| DEP Holdings Ltd | Professional & scientific | 2021 |
| Dependable Management Limited | Real estate | 2013 |
| Derby Care Pharma Co., Ltd. | Extraterritorial | 2012 |
| Derek Evans Project Management Limited | Extraterritorial | 1987 |
| Derek Machin and SON Limited | Administrative & support | 2001 |
| Derick Lewis Tipper Services Limited | Transport & logistics | 2018 |
| Derrington Motor Services Limited | Extraterritorial | 2010 |
| Desb Limited | Real estate | 2025 |
| Deserto Rosso Limited | Information & communication | 2021 |
| Desford Property Ltd | Real estate | 2020 |
| Design I X Ltd. | Information & communication | 2011 |
| Designer Curtains (Staffs) Limited | Manufacturing | 2002 |
| Desirous Horses Ltd | Agriculture & fishing | 2025 |
| Detaverse Ltd | Agriculture & fishing | 2022 |
| Deting Tourism Investment Co., Limited | Hospitality | 2024 |
| Devallion Ltd | Professional & scientific | 2024 |
| Devaney & Co Limited | Wholesale & retail | 2021 |
| Devco Padel Limited | Arts & recreation | 2025 |
| Development Worx Limited | Construction | 2015 |
| Devi-Malar Ltd | Real estate | 2025 |
| Devils Haircut Limited | Other services | 2011 |
| Devo Goalsport Ltd | Manufacturing | 2019 |
| Devo Organics Ltd | Other services | 2022 |
| Dewbar Limited | Real estate | 1978 |
| Dewsbury Holdings Ltd | Financial services | 2021 |
| DFD Trading Co., Limited | Wholesale & retail | 2024 |
| DFH Engineering Ltd. | Manufacturing | 2016 |
| Dfjwnssxaq Ltd | Wholesale & retail | 2026 |
| Dfmr Enterprises Limited | Other services | 2015 |
| DG Sound & Light Limited | Administrative & support | 2017 |
| DGL Networks Limited | Information & communication | 2013 |
| Dgs&Co Ltd | Administrative & support | 2024 |
| DH Electrical (Staffordshire) Ltd | Construction | 2024 |
| DH Governance Ltd | Professional & scientific | 2017 |
| DH Home Improvements Ltd | Construction | 2025 |
| DHZ Contracting Limited | Construction | 2017 |
| Diagnosticus Limited | Professional & scientific | 2013 |
| Diamond Alarms Ltd | Construction | 2018 |
| Diarra Group Sarl Trading Company Ltd | Manufacturing | 2025 |
| Dias Holdings Limited | Financial services | 2019 |
| Diecasting Society Limited (the) | Other services | 1969 |
| Diesel Emission Control Limited | Manufacturing | 2009 |
| Diesel Marine International Limited | Professional & scientific | 2001 |
| Diet & Behaviour Expert Ltd | Other services | 2024 |
| Digihub Connect Ltd | Manufacturing | 2025 |
| Digital Defined Ltd | Information & communication | 2020 |
| Digital Globe (UK) Company Limited | Wholesale & retail | 2024 |
| Digital Itch Ltd | Administrative & support | 2010 |
| Digrunner Limited | Information & communication | 2021 |
| Dinham Property Services Limited | Real estate | 2020 |
| Dinko Limited | Wholesale & retail | 2015 |
| Dintel Limited | Professional & scientific | 2016 |
| Direct Holiday Homes Limited | Other services | 2006 |
| Direct Legal Limited | Professional & scientific | 2025 |
| Direct Loads Limited | Transport & logistics | 2024 |
| Direct Plant Maintenance Ltd | Wholesale & retail | 2016 |
| Direct Practitioner Ltd | Health & social care | 2023 |
| Disapp Limited | Financial services | 1999 |
| Disbury Creative Limited | Professional & scientific | 2020 |
| Distinguished Aesthetics Ltd | Other services | 2023 |
| Divine Equestrian Limited | Wholesale & retail | 2015 |
| Division Detailing Ltd | Wholesale & retail | 2026 |
| Dixon Construction (Stafford) Limited | Construction | 2007 |
| Dixon's of Telford Ltd | Wholesale & retail | 2019 |
| Diya Enterprises Limited | Health & social care | 2019 |
| Diyapo Co., Ltd | Wholesale & retail | 2025 |
| DIYODI7 Ltd | Transport & logistics | 2018 |
| DJ Builders (Stafford) Ltd | Construction | 2004 |
| DJ Collections UK Limited | Wholesale & retail | 2025 |
| DJ DAS Estates Ltd | Real estate | 2024 |
| DJ DAS Stores Ltd | Wholesale & retail | 2025 |
| DJ EQ Ltd | Information & communication | 2024 |
| DJ Signature Sports Limited | Wholesale & retail | 2025 |
| DJ Tech Ltd | Wholesale & retail | 2024 |
| DJS (Staffordshire) Ltd | Construction | 2021 |
| Djtantoh Limited | Transport & logistics | 2025 |
| DL & SJ Hill Property Investments Ltd | Real estate | 2026 |