| Somal School Uniforms Ltd | Wholesale & retail | 2025 |
| Soni Transfer Limited | Financial services | 2017 |
| Sonic Speed Logistics Limited | Transport & logistics | 2023 |
| Soomal Electrics Ltd | Construction | 2026 |
| Sophitoms Ltd | Transport & logistics | 2024 |
| Sorbex Recruits Ltd | Administrative & support | 2021 |
| SOURCE4 Trading Limited | Hospitality | 2007 |
| South Bay Construction Ltd | Construction | 2025 |
| Sovereign Coaching Limited | Education | 2023 |
| Sovereign K9 Limited | Agriculture & fishing | 2017 |
| SOW Seeds SOW Limited | Manufacturing | 2017 |
| SP Aujla Ltd | Wholesale & retail | 2011 |
| SP04 Ltd | Wholesale & retail | 2025 |
| Space Logistics Ltd | Transport & logistics | 2017 |
| SPACES4LESS Ltd | Real estate | 2023 |
| Spacious Place Developments Limited | Construction | 2017 |
| Sparow Express Ltd | Transport & logistics | 2025 |
| Spartan Business Ltd | Water & waste | 2020 |
| Special Events Photo Booths Ltd | Professional & scientific | 2025 |
| Specialist Repair Network Ltd | Construction | 2026 |
| Spectra Arts CIC | Arts & recreation | 2018 |
| Spectrum Safety & Janitorial Supplies Limited | Wholesale & retail | 2008 |
| Speed Run Courier Ltd | Transport & logistics | 2024 |
| Speedy Deliveries U.K. Ltd | Transport & logistics | 2025 |
| Speedy Eagle Ltd | Transport & logistics | 2025 |
| Speedy Logistics Ltd | Transport & logistics | 2017 |
| Spesh PM Limited | Professional & scientific | 2021 |
| Spice Fusion Dudley Ltd | Hospitality | 2025 |
| Spire Key Property Limited | Real estate | 2024 |
| Sponsormyfutures Ltd | Education | 2025 |
| Spotless Hand Carwash Ltd | Administrative & support | 2017 |
| Spotless Point Limited | Hospitality | 2019 |
| Spotless Solutions Cleaning Services Limited | Administrative & support | 2026 |
| Spreebay Ltd | Wholesale & retail | 2025 |
| Sprinter IT Ltd | Construction | 2020 |
| Sprinter Projects Ltd | Construction | 2020 |
| Sprinter Solutions Ltd | Construction | 2020 |
| Sprinter Systems Ltd | Construction | 2020 |
| SQ Enterprises Ltd | Wholesale & retail | 2023 |
| SR Building Services Ltd | Construction | 2026 |
| SR Motor Specialist Ltd | Wholesale & retail | 2026 |
| Srhk Limited | Hospitality | 2026 |
| SRI Guru Nanak Mission Ltd | Health & social care | 2021 |
| SRI Payroll Services Ltd | Professional & scientific | 2021 |
| SRI Tax Accountants Limited | Professional & scientific | 2012 |
| SRM Auto’S Limited | Wholesale & retail | 2026 |
| SS and JK Company Limited | Real estate | 2026 |
| SS Civil Engineering Ltd | Construction | 2018 |
| SS Properties Services Limited | Real estate | 2019 |
| SS Trading (Birmingham) Ltd | Wholesale & retail | 2023 |
| SS Trans Services Ltd | Construction | 2026 |
| SSB Building Repairs Ltd | Construction | 2025 |
| SSB Construction Ltd | Manufacturing | 2019 |
| SSB Properties (Mids) Ltd | Real estate | 2023 |
| SSC Stores Ltd | Wholesale & retail | 2024 |
| SSK Transport Ltd | Transport & logistics | 2025 |
| SSS Transport U.K. Limited | Transport & logistics | 2025 |
| SSS Transport WM Ltd | Transport & logistics | 2025 |
| ST Albans Community Association | Hospitality | 2007 |
| ST Andrews Foods (Midlands) Ltd | Hospitality | 2018 |
| ST Bernards Care Home Ltd | Health & social care | 1996 |
| ST Christie Care Ltd | Wholesale & retail | 2024 |
| ST Pauls Healthcare Limited | Health & social care | 2013 |
| ST Services (UK) Ltd | Transport & logistics | 2014 |
| ST. Nicholas House Ltd | Administrative & support | 2005 |
| Staffordshire Town Holdings Ltd | Hospitality | 2023 |
| Stage Cafe Lounge Ltd | Hospitality | 2026 |
| Stage Lounge Ltd | Hospitality | 2025 |
| Stallion Housing Ltd | Households | 2019 |
| Stallion Transport Ltd | Transport & logistics | 2026 |
| Stan 105 Trans Ltd | Administrative & support | 2011 |
| Standard Tandoori Restaurant Ltd | Hospitality | 2023 |
| Stanfield Software Ltd | Construction | 2020 |
| Stanford Systems Ltd | Construction | 2020 |
| Stanley Doal Developments Ltd | Real estate | 2023 |
| Staple Properties Ltd | Real estate | 2026 |
| Staplefordhub Ltd | Construction | 2023 |
| Star African Village Ltd | Hospitality | 2016 |
| Star Bazaar Limited | Wholesale & retail | 2023 |
| Star Day Care Limited | Health & social care | 2026 |
| Star Halal Meat Ltd | Wholesale & retail | 2024 |
| Star Light Cafe Limited | Hospitality | 2022 |
| Star Music and Production Ltd | Hospitality | 2025 |
| Star Signs & Displays Ltd | Manufacturing | 2023 |
| Star Student Support Ltd | Education | 2019 |
| Star Supermarket Stores Limited | Wholesale & retail | 2021 |
| Star Superstore Ltd | Wholesale & retail | 2023 |
| Star Windows 2000 Limited | Construction | 2019 |
| Stargrill Pizza Ltd | Wholesale & retail | 2023 |
| Starlight (East London) Limited | Manufacturing | 2025 |
| Starlink Travel WM Ltd | Transport & logistics | 2025 |
| Staron Interiors Ltd | Manufacturing | 2022 |
| Starshine Flooring Ltd | Construction | 2017 |
| Stay Focused Fitness Limited | Health & social care | 2023 |
| Stayspark Cleaning Ltd | Administrative & support | 2026 |
| Steel Fence Supplies Limited | Extraterritorial | 1984 |
| Steelmax Limited | Construction | 2025 |
| Stefan GG Ltd | Transport & logistics | 2026 |
| Stefcargo Ltd | Transport & logistics | 2025 |
| Stella Properties Ltd | Real estate | 2026 |