| Stem Computers Ltd | Construction | 2020 |
| Sten Health Care Ltd | Health & social care | 2024 |
| Step by Step Tutors Ltd | Education | 2023 |
| Step Change Technology Ltd | Wholesale & retail | 2017 |
| Step UP Accommodation Limited | Hospitality | 2025 |
| Stepping Stone Nursery Limited | Health & social care | 2019 |
| Steppingstones in the Community (Sitc) C.I.C. | Education | 2023 |
| Steps to Sikhi Limited | Information & communication | 2025 |
| Sterling Kitchen Makeover Ltd | Construction | 2026 |
| Sterling Support Group Ltd | Professional & scientific | 2026 |
| Sterling Transport Ltd | Transport & logistics | 2026 |
| Steven Barnes & SON Ltd | Construction | 2026 |
| Stitches Ltd | Manufacturing | 2020 |
| STL Events Ltd | Arts & recreation | 2024 |
| Stockport Ventures Pizza Limited | Hospitality | 2017 |
| Stolowa Ltd | Manufacturing | 2017 |
| Stonebake Pizza Ltd | Hospitality | 2016 |
| Stonecrest Estates Limited | Real estate | 2025 |
| Stonecross HS Ltd | Hospitality | 2024 |
| Stonelion Records Limited | Arts & recreation | 2019 |
| Stonix Tiles and Bathrooms Ltd | Construction | 2025 |
| Storm Empire Ltd | Real estate | 2024 |
| Stratum Properties PTE Ltd | Real estate | 2015 |
| Straza Studios Ltd | Information & communication | 2017 |
| Streamline Power Solutions Ltd | Construction | 2025 |
| Street Ansar CIC | Education | 2022 |
| Stronghold Labour Ltd | Administrative & support | 2025 |
| Structural Sections Limited | Extraterritorial | 1985 |
| Structvil Ltd | Construction | 2022 |
| Struko Group Ltd | Construction | 2025 |
| Studio Gotz Limited | Professional & scientific | 2018 |
| Studiocrest Ltd | Information & communication | 2025 |
| Study With Sindi Limited | Education | 2024 |
| Style Windows & Construction Ltd | Manufacturing | 2025 |
| Stylo Homes Ltd | Real estate | 2021 |
| Suba Singh Ltd | Construction | 2025 |
| Sublime Basketball Ltd | Arts & recreation | 2017 |
| Suiting Style Limited | Wholesale & retail | 2021 |
| Suits U Walsall Ltd | Manufacturing | 2022 |
| Sun Developments WM Ltd | Construction | 2020 |
| Sunrise Computers Ltd | Construction | 2020 |
| Sunrise Construction U.K. Ltd | Construction | 2025 |
| Sunset Computers Ltd | Construction | 2020 |
| Super Food Market Ltd | Wholesale & retail | 2026 |
| Super Shining Hand Car Wash Ltd | Administrative & support | 2025 |
| Super Star CW Ltd | Administrative & support | 2026 |
| Superior Interior Designs Limited | Wholesale & retail | 2024 |
| Supersonic Despatch Limited | Transport & logistics | 2016 |
| Supertouch Industrial Supplies Limited | Professional & scientific | 1999 |
| Supreme Brands Ltd | Wholesale & retail | 2022 |
| Supreme Builders Merchants Ltd | Construction | 2021 |
| Suraj P Holdings Limited | Real estate | 2017 |
| Sure LET Midlands Ltd | Real estate | 2026 |
| Sustainability Edge Certified Consultants Ltd | Professional & scientific | 2026 |
| Sutton Outdoor Preschool Ltd. | Education | 2017 |
| Sutton Products Limited | Administrative & support | 2011 |
| Suttons Investments Limited | Real estate | 2022 |
| SV Housing Limited | Real estate | 2025 |
| SW PJ Admin Ltd | Administrative & support | 2024 |
| Swayze Ltd | Construction | 2026 |
| Sweet Cakes by Liliana&Ema Ltd | Wholesale & retail | 2025 |
| Sweet RNB Limited | Arts & recreation | 2019 |
| Sweethive Enterprise Limited | Agriculture & fishing | 2020 |
| Swift Grub Limited | Information & communication | 2025 |
| Swiftgo Couriers Ltd | Transport & logistics | 2025 |
| SY Building Contractor Limited | Construction | 2019 |
| SY Midland Ltd | Construction | 2020 |
| SY Property Group Ltd | Real estate | 2021 |
| Sycagaminghouse Ltd | Other services | 2026 |
| Sylix Limited | Health & social care | 2025 |
| SYM Traders Limited | Wholesale & retail | 2025 |
| Synergy Shipping Group Limited | Transport & logistics | 2023 |
| Synex Technology Limited | Information & communication | 2025 |
| Systemais Group Limited | Information & communication | 2025 |
| Szaman Consultancy Limited | Professional & scientific | 2025 |
| SZZ Property Services Ltd | Households | 2021 |
| T & D Properties (Midlands) Limited | Real estate | 2020 |
| T & E Displays(Uk) Ltd | Manufacturing | 2015 |
| T &K Traders Ltd | Construction | 2021 |
| T Hussain Enterprises Ltd | Other services | 2023 |
| T Structure Ltd | Construction | 2026 |
| T&G Home Improvements Ltd | Construction | 2023 |
| T&T Commercial Properties Ltd | Real estate | 2024 |
| T&T Living Ltd | Real estate | 2020 |
| T&T Pharma Healthcare Ltd | Professional & scientific | 2020 |
| T4PE Group Ltd | Information & communication | 2022 |
| Taaro Ltd | Wholesale & retail | 2025 |
| Taas Retail Limited | Wholesale & retail | 2021 |
| Tabz Consultancy Services Limited | Health & social care | 2019 |
| Tactic Immigration and Asylum Training Consultancy Research CIC | Professional & scientific | 2020 |
| Tadkaa Kingdom Ltd | Wholesale & retail | 2022 |
| Taimani Ltd | Wholesale & retail | 2018 |
| Taimoor Ltd | Wholesale & retail | 2024 |
| Taipan Line Ltd | Transport & logistics | 2014 |
| Takhar Estate Agent Limited | Real estate | 2019 |
| Takhar Travel Limited | Administrative & support | 2009 |
| Tameemi Services Limited | Transport & logistics | 2026 |
| Tamir Wyne Limited | Wholesale & retail | 2021 |
| Tamu Brum Limited | Hospitality | 2019 |
| Tamynath Ltd | Wholesale & retail | 2024 |