| SAI Stores Limited | Wholesale & retail | 2020 |
| Sai-Pp Property Limited | Real estate | 2022 |
| Saif Enterprises Ltd | Administrative & support | 2016 |
| Saif Transport Ltd | Transport & logistics | 2025 |
| Saif’S Boxing and Fitness Ltd | Arts & recreation | 2020 |
| SAIGON68 Vietnamese Cafe Limited | Hospitality | 2024 |
| Saint Armstrong Ltd | Manufacturing | 2020 |
| Saint Charles Ltd | Wholesale & retail | 2025 |
| Saint Consultancy Services Limited | Administrative & support | 2009 |
| Saint Margarets Tavern Limited | Hospitality | 2025 |
| Saint Promotions Limited | Administrative & support | 2012 |
| Saint-Tropez Limited | Real estate | 2023 |
| Saintsaestheticsuk Ltd | Other services | 2019 |
| Sainty Ltd | Professional & scientific | 2023 |
| Saiti Ltd | Mining & quarrying | 2023 |
| SAJ Services Ltd | Wholesale & retail | 2009 |
| Saken Systems Ltd | Extraterritorial | 2020 |
| Sakhr Trading Ltd | Financial services | 2024 |
| Sakushi Restaurant Limited | Hospitality | 2024 |
| SAL AI Studios Ltd | Information & communication | 2026 |
| Salad Security Services Ltd | Administrative & support | 2026 |
| Salah Delivery Solutions Limited | Transport & logistics | 2025 |
| Sale Hill Close Property Company Limited | Households | 2021 |
| Sale Hill Freehold Limited | Real estate | 2016 |
| Saleem & Sons Properties Ltd | Real estate | 2026 |
| Saleem Flooring Limited | Construction | 2019 |
| Saleems Barber Shop Ltd | Other services | 2026 |
| Saleh Scents Ltd | Wholesale & retail | 2026 |
| Sales & Commercial Solutions Ltd | Professional & scientific | 2016 |
| Sales and Marketing Solutions Limited | Wholesale & retail | 2018 |
| Sales Force 10 Recruitment Ltd | Administrative & support | 2014 |
| Sales Geek Sheffield Limited | Professional & scientific | 2022 |
| Salesoft Ltd | Information & communication | 2018 |
| Salesquared Limited | Wholesale & retail | 2021 |
| Salestribe International Ltd | Professional & scientific | 2021 |
| Salford Metal Finishing Ltd | Extraterritorial | 2015 |
| Sali Limited | Administrative & support | 2026 |
| Salkara Taste of India Limited | Hospitality | 2025 |
| Sall Deliveries Limited | Transport & logistics | 2026 |
| Sall Properties Ltd | Real estate | 2025 |
| Salleh-Group CIC | Health & social care | 2025 |
| Sallianne Wild Ltd | Health & social care | 2017 |
| Sally Fawcett Physio and PT Ltd | Other services | 2011 |
| Sally Food Ltd | Hospitality | 2019 |
| Sally Kitchen Ltd | Wholesale & retail | 2025 |
| Salon 187 Ltd | Other services | 2025 |
| Salon 60 Ltd | Other services | 2021 |
| Salon Consultants Limited | Professional & scientific | 2015 |
| Sals Beddings and Furniture Ltd | Wholesale & retail | 2024 |
| Salsido Ltd | Hospitality | 2018 |
| Salso Properties Limited | Real estate | 2025 |
| Salstone Aggregates Ltd | Wholesale & retail | 2025 |
| Salt & Foam Wibsey Ltd | Hospitality | 2020 |
| Salt & Vineger Fish & Chips Ltd | Hospitality | 2026 |
| Salt Labsystem Limited | Information & communication | 2022 |
| Salt N Pepper Enterprises Limited | Extraterritorial | 2013 |
| Saltaire Holdings Limited | Real estate | 2025 |
| Saltbox House Ltd | Professional & scientific | 2023 |
| Saltbox Solutions Ltd | Professional & scientific | 2023 |
| Salticus Ltd | Real estate | 2023 |
| Saltire Rose Limited | Hospitality | 2024 |
| Saltire Rose Property Limited | Real estate | 2025 |
| Saltwoodend Limited | Real estate | 2004 |
| Salud LS Limited | Wholesale & retail | 2023 |
| Salus Health and Wellbeing Limited | Arts & recreation | 2024 |
| Salva Property Ltd | Real estate | 2024 |
| Salvage Link Ltd | Administrative & support | 2025 |
| Salvex Motors Ltd | Wholesale & retail | 2026 |
| Salvin Developments Ltd | Construction | 2020 |
| Salvin Property Holdings Ltd | Real estate | 2019 |
| Salvin-Hughes Property Holdings Ltd | Real estate | 2019 |
| Salvins Support Services Ltd | Administrative & support | 2023 |
| SAM (Sheff) Ltd | Real estate | 2025 |
| SAM Bailey Landscape Architecture Ltd | Professional & scientific | 2024 |
| SAM Care Support Services Ltd | Health & social care | 2025 |
| SAM Donovan Limited | Information & communication | 2012 |
| SAM Evans Build Limited | Construction | 2022 |
| SAM Norbron Electrical Services Ltd | Construction | 2013 |
| SAM Parkin Media Limited | Arts & recreation | 2021 |
| SAM Ring Furniture Limited | Manufacturing | 2019 |
| SAM Twiselton Ltd | Professional & scientific | 2023 |
| SAM Walker Marketing and Copywriting Limited | Professional & scientific | 2012 |
| Sam-Sold Ltd | Wholesale & retail | 2023 |
| Sama Global Consulting Ltd | Professional & scientific | 2021 |
| Samaa Studio Ltd | Professional & scientific | 2023 |
| Samad Food Limited | Hospitality | 2026 |
| Samada Naija Kitchen Limited | Hospitality | 2025 |
| Samahoma Limited | Information & communication | 2014 |
| Saman Travels Limited | Administrative & support | 2024 |
| Samantha Day Colour Ltd | Information & communication | 2020 |
| Samara Limited | Administrative & support | 1993 |
| Samara Lounge Ltd | Hospitality | 2020 |
| Samari Digital Limited | Professional & scientific | 2023 |
| Samarise Ltd | Wholesale & retail | 2025 |
| Samaspire Limited | Information & communication | 2026 |
| Samay Holiday Homes Ltd | Real estate | 2020 |
| Samay Properties Limited | Real estate | 2016 |
| Samcharles Limited | Real estate | 2025 |
| Samdai Ltd | Transport & logistics | 2019 |
| Same Basis Ltd | Information & communication | 2026 |