| SA Cafe Restaurant Limited | Hospitality | 2024 |
| SA Engagements Ltd | Professional & scientific | 2022 |
| SA Hospitality Ltd | Hospitality | 2025 |
| SA Property Lettings Ltd | Real estate | 2021 |
| SA Securities Ltd | Hospitality | 2004 |
| SA Valeting Servicing Limited | Other services | 2024 |
| Sa&Si Cleaning Services Ltd | Administrative & support | 2025 |
| Sa-Sa Studio Group Limited | Wholesale & retail | 2026 |
| Saak Foods UK Ltd | Wholesale & retail | 2023 |
| Saalik Youth Project Ltd | Arts & recreation | 2020 |
| Saaprime Solutions Limited | Professional & scientific | 2025 |
| Saar Medical Ltd | Health & social care | 2024 |
| Saatip Analytics Limited | Professional & scientific | 2025 |
| SAB DAV Limited | Construction | 2021 |
| Saba & Meron Ltd | Real estate | 2023 |
| Saba Accountants & Tax Advisors Ltd | Professional & scientific | 2025 |
| Saba Musk Ltd | Wholesale & retail | 2026 |
| Sabbc Limited | Wholesale & retail | 2022 |
| Sabby E CIG Ltd | Wholesale & retail | 2024 |
| Sabeeh Limited | Professional & scientific | 2023 |
| Sabenz Ltd | Hospitality | 2018 |
| Sabir Cabs Sheffield Ltd | Transport & logistics | 2022 |
| Sabir's Spicy Grill Bar Limited | Hospitality | 2017 |
| Sable Creative Ltd | Professional & scientific | 2014 |
| Sabr and Stride CIC | Arts & recreation | 2025 |
| Sabre Conversions Ltd | Other services | 2025 |
| Sabre Heating Ltd | Construction | 2009 |
| Sabre Toolmaking Limited | Manufacturing | 2003 |
| Sabre Trace and Recovery Ltd | Administrative & support | 2022 |
| Sabrebond Limited | Wholesale & retail | 1985 |
| Sabrenza Ltd | Administrative & support | 2024 |
| Sabstar Beauty Limited | Wholesale & retail | 2025 |
| Sabz Ltd | Hospitality | 2008 |
| Sacred ZEN Shop Ltd | Wholesale & retail | 2025 |
| Saddique a 2 Z Ltd | Transport & logistics | 2020 |
| Saddlealign Ltd | Health & social care | 2025 |
| Sadler Tankers Limited | Extraterritorial | 1989 |
| Saecotec Ltd | Other services | 2023 |
| Saed Bakery Limited | Wholesale & retail | 2023 |
| Saeedahmad Ltd | Wholesale & retail | 2025 |
| Saeedstone Properties Limited | Real estate | 2026 |
| SAF Beds & Furnishings Ltd | Wholesale & retail | 2020 |
| SAF Investment Group Limited | Real estate | 2026 |
| SAF Jewellery Limited | Wholesale & retail | 2021 |
| Safaat Sales Ltd | Wholesale & retail | 2026 |
| Safak Wood Fish Ltd | Hospitality | 2025 |
| Safari Solutions Limited | Information & communication | 2022 |
| Safe Alternative Centre C.I.C. | Education | 2015 |
| Safe Bright Limited | Construction | 2018 |
| Safe Care Training Limited | Professional & scientific | 2023 |
| Safe Data Systems Ltd | Information & communication | 2017 |
| Safe Haven Adolescent Care Group Limited | Health & social care | 2019 |
| Safe Homes Property Management Limited | Real estate | 2023 |
| Safe Lane Driving School Ltd | Education | 2025 |
| Safe Life Training Limited | Health & social care | 2014 |
| Safe Scene Solutions Ltd | Water & waste | 2025 |
| Safe-Edge Limited | Construction | 1991 |
| Safe-Ways Fire and Security Ltd | Manufacturing | 2010 |
| Safeair Heatstream Limited | Manufacturing | 2015 |
| Safeguard VP Limited | Manufacturing | 2023 |
| Safenet Alarms Limited | Manufacturing | 2011 |
| Safenet Protection Limited | Administrative & support | 2024 |
| Safeplace Limited | Information & communication | 1985 |
| Safepulse Limited | Administrative & support | 2025 |
| Safequote Ltd | Administrative & support | 2024 |
| Safer Online Gambling Group CIC | Professional & scientific | 2019 |
| Safer Staffing Solutions Ltd | Health & social care | 2018 |
| Safestaybb Ltd | Hospitality | 2024 |
| Safetask Limited | Construction | 1988 |
| Safetrain Limited | Education | 2010 |
| Safety Aloft Limited | Administrative & support | 2015 |
| Safety and Health Hub Ltd | Wholesale & retail | 2025 |
| Safety Fabrications Limited | Manufacturing | 2006 |
| Safety Guards Limited | Manufacturing | 2009 |
| Safety Netting & Edge Protection Specialists UK Ltd | Construction | 2024 |
| Safety Republic Limited | Wholesale & retail | 2008 |
| Safetykit UK Ltd | Administrative & support | 2004 |
| Safewalkmaps Ltd | Information & communication | 2025 |
| Safewatch Limited | Administrative & support | 2025 |
| Safeway Forwarding Limited | Transport & logistics | 2012 |
| Safeway Services & More Ltd | Other services | 2012 |
| Saffron Thai Wellness Ltd | Other services | 2026 |
| Safira Limited | Real estate | 2019 |
| Saga Force Limited | Wholesale & retail | 2025 |
| SAGA7 Enterprises Ltd | Information & communication | 2019 |
| Sage Collective Community Interest Company | Education | 2026 |
| Sage Pubs Limited | Hospitality | 2023 |
| Sagepoint Consultancy Limited | Information & communication | 2025 |
| Sagieventures Ltd | Information & communication | 2025 |
| Sagnde Business Ltd | Wholesale & retail | 2025 |
| Saha Property Consultants Ltd | Hospitality | 2026 |
| Sahab Company Limited | Health & social care | 2008 |
| Sahand Wholesale Ltd | Wholesale & retail | 2025 |
| Saharsh IT Consultants Private Limited | Other services | 2014 |
| Sahithi SAH Ltd | Hospitality | 2024 |
| Sahm Consulting Ltd | Wholesale & retail | 2022 |
| SAI Housing Ltd | Real estate | 2020 |
| SAI Innovation Limited | Real estate | 2009 |
| SAI KM Ltd | Professional & scientific | 2017 |
| SAI Saranam Healthcare Limited | Wholesale & retail | 2026 |