| Sandbach Construction Ltd | Construction | 2017 |
| Sandbach Craftworks Ltd | Arts & recreation | 2023 |
| Sandbach Demolition Ltd | Construction | 2021 |
| Sandbach Desserts Limited | Hospitality | 2025 |
| Sandbach Developments Limited | Construction | 2018 |
| Sandbach Golf Club Ltd | Arts & recreation | 2024 |
| Sandbach Gymnastics Foundation | Health & social care | 2017 |
| Sandbach Health and Fitness Limited | Health & social care | 2017 |
| Sandbach Health and Fitness Studio Limited | Health & social care | 2019 |
| Sandbach High School and Sixth Form College | Education | 2010 |
| Sandbach Indian Restaurant Limited | Hospitality | 2024 |
| Sandbach Minimarket Ltd | Wholesale & retail | 2025 |
| Sandbach Motor Factors Ltd | Wholesale & retail | 2025 |
| Sandbach Mowers and Repairs Limited | Extraterritorial | 2020 |
| Sandbach Music S&P Limited | Wholesale & retail | 2024 |
| Sandbach Podiatry Ltd | Health & social care | 2014 |
| Sandbach Poultry Limited | Wholesale & retail | 2018 |
| Sandbach Pride CIC | Other services | 2022 |
| Sandbach Repair Centre Limited | Wholesale & retail | 2021 |
| Sandbach Resin Floors Ltd | Construction | 2023 |
| Sandbach Roofing Contractors Ltd | Construction | 2008 |
| Sandbach Rugby Club Trading Limited | Arts & recreation | 2017 |
| Sandbach Rugby Football Club Limited | Arts & recreation | 2019 |
| Sandbach School | Education | 2008 |
| Sandbach School Developments Limited | Arts & recreation | 2008 |
| Sandbach Slot Cars Ltd | Wholesale & retail | 2020 |
| Sandbach Storage Limited | Transport & logistics | 2016 |
| Sandbach Truck and Van Limited | Wholesale & retail | 2015 |
| Sanders Business Consultancy Ltd | Professional & scientific | 2020 |
| Sandfield Limited | Health & social care | 2023 |
| Santune Meadows Ltd | Construction | 2020 |
| Satsafe Limited | Professional & scientific | 2013 |
| Saxon Cross Holdings Limited | Other services | 2018 |
| SAY the Word Ltd | Arts & recreation | 2026 |
| Sayoui Limited | Wholesale & retail | 2024 |
| SBK Consulting Services Limited | Professional & scientific | 2023 |
| SC Adhd Consultancy Ltd | Administrative & support | 2023 |
| Scala Equestrian Products Ltd | Agriculture & fishing | 2021 |
| Scotts Contracting Limited | Professional & scientific | 2018 |
| Scotts Hire Limited | Administrative & support | 2008 |
| Scotts Vehicle Holdings Limited | Administrative & support | 2006 |
| SCP Private Hire Ltd | Transport & logistics | 2021 |
| SCW Transport Services Ltd | Transport & logistics | 2026 |
| SDB Windows and Doors Limited | Construction | 2018 |
| Sdls Properties Ltd | Real estate | 2020 |
| Seabridge Design & Build Ltd | Real estate | 2020 |
| Secal TKS Ltd | Professional & scientific | 2021 |
| Seeds of Success Ltd | Information & communication | 2022 |
| Selwyn Carbutt Limited | Agriculture & fishing | 1998 |
| Sensational Bathrooms Limited | Wholesale & retail | 2022 |
| Sentimental Properties Limited | Real estate | 2020 |
| Serecena SIX Limited | Administrative & support | 2005 |
| Seriba Limited | Real estate | 2020 |
| Sesmars Limited | Administrative & support | 2025 |
| Setsquare Consulting Ltd | Professional & scientific | 2007 |
| Setsquare Properties Ltd | Real estate | 2019 |
| SGA Specialist Services LLP | | 2013 |
| Shack and Sons Ltd | Construction | 2024 |
| Shannon Holdings Limited | Financial services | 2021 |
| Shannon Properties Limited | Real estate | 2013 |
| Shanscape Services Ltd | Transport & logistics | 2024 |
| Sheamar Holdings Ltd | Financial services | 2024 |
| Shepherds View (Freehold) Ltd | Real estate | 2026 |
| Shopwrs Ltd | Wholesale & retail | 2024 |
| Showreel Media Ltd | Manufacturing | 2020 |
| Shred to BED Ltd | Water & waste | 2020 |
| Shutters by Design Ltd | Professional & scientific | 2013 |
| SI SI Catering Limited | Hospitality | 2023 |
| Sifolinis Limited | Transport & logistics | 2025 |
| Silk and Stone Interior Design Ltd | Professional & scientific | 2022 |
| Siltrad Properties Limited | Real estate | 2013 |
| Silver Forest Limited | Information & communication | 2021 |
| Silver Terrace Management Company Limited | Households | 2022 |
| Simmons of Cheshire Ltd | Real estate | 2020 |
| Simon Green Site Engineering Ltd | Construction | 2013 |
| Simon Whitby AD2 Ltd | Arts & recreation | 2017 |
| Simply Litigation Limited | Administrative & support | 2015 |
| Simply Property Holdings Limited | Real estate | 2016 |
| Singlotech Limited | Manufacturing | 2019 |
| Sisu SCR Ltd | Other services | 2011 |
| Siun Associates Ltd | Information & communication | 2021 |
| Sjls Property Limited | Real estate | 2023 |
| Skenikos Limited | Households | 2018 |
| Skill Supply Limited | Education | 2014 |
| Skinsmiths Tattoos Ltd | Other services | 2022 |
| SL Plumbing and Heating Services Ltd | Construction | 2025 |
| Sloss Engineering Services Ltd | Manufacturing | 2018 |
| Smallwood Forge Residents Association Limited | Households | 1998 |
| Smallwood Vintage Rally Camping Ltd | Hospitality | 2023 |
| Smallwood Vintage Rally Catering Ltd | Hospitality | 2023 |
| Smallwood Vintage Rally Ltd | Arts & recreation | 2021 |
| Smart Machinery Services Limited | Information & communication | 2026 |
| Smashd Sandbach Ltd | Hospitality | 2025 |
| Smethwick Hall Barns Limited | Professional & scientific | 2012 |
| Smith Home Solutions Ltd | Real estate | 2025 |
| Smooth Dent Removal Limited | Wholesale & retail | 2016 |
| SMR Mechanical Ltd | Construction | 2026 |
| Snapkeep Ltd | Wholesale & retail | 2026 |
| Snowdrop Developments Limited | Construction | 1992 |
| Soak Limited | Manufacturing | 2016 |