| Solaris Cleanenergy Co Ltd | Construction | 2025 |
| Solomon and Sons Limited | Professional & scientific | 2025 |
| Soma Events Ltd | Hospitality | 2016 |
| Somerford Equipment Limited | Manufacturing | 2010 |
| South Cheshire Property Limited | Real estate | 2021 |
| South Herts DAB Ltd | Information & communication | 2023 |
| Spacecore Web Ltd | Professional & scientific | 2026 |
| Sparrow Grove Management Limited | Real estate | 2015 |
| Sparrowgrove Estates Limited | Real estate | 2025 |
| Speck ABC UK Ltd. | Manufacturing | 1996 |
| Speelang Limited | Health & social care | 2010 |
| Spiky Carrot Ltd | Information & communication | 2019 |
| Spinnaker Aero Limited | Professional & scientific | 2019 |
| Splash and Dash Supplies Ltd | Administrative & support | 2026 |
| Sports Igloo Limited | Information & communication | 2023 |
| Springfield Estate Management Limited | Households | 2018 |
| SPS Capricorn Limited | Transport & logistics | 2019 |
| Spur Enterprises Limited | Professional & scientific | 2013 |
| Squatch Prop 1 Limited | Real estate | 2025 |
| SRJ Willis Holding Limited | Financial services | 2025 |
| ST John's Pre-School Nursery Limited | Education | 2016 |
| Staff Only Training Limited | Construction | 2022 |
| Stafford Fencing & Landscaping Ltd | Construction | 2020 |
| Staffordshire Spine Clinic (MF Brown) Limited | Health & social care | 2010 |
| Stainless Automotive Fastenings Limited | Professional & scientific | 2009 |
| Stanmore Health Ltd | Health & social care | 2017 |
| Stapling & Nailing Ltd. | Professional & scientific | 2017 |
| Stem Skill Clubs Franchising Ltd | Administrative & support | 2026 |
| Step by Step Estate Planning Limited | Professional & scientific | 2018 |
| Stephen Irlam Site Managment Services Limited | Construction | 2016 |
| Stephenson Poultry Services Ltd | Wholesale & retail | 2014 |
| Stepping Stones Montessori Childcare Limited | Education | 2010 |
| Sterling Path Investment Group Limited | Financial services | 2026 |
| Stickle Brick Properties Limited | Real estate | 2017 |
| Stitchcraft Limited | Manufacturing | 2015 |
| Stormtech Support Limited | Information & communication | 2014 |
| Straight 2 Site Ltd | Wholesale & retail | 2017 |
| Street Light DGS Limited | Arts & recreation | 2017 |
| Strianach Ltd | Wholesale & retail | 2015 |
| Studio Miley Ltd | Information & communication | 2023 |
| Studio UX Limited | Information & communication | 2014 |
| Styal Apartments Limited | Real estate | 2021 |
| Styal Groundworks Limited | Construction | 2013 |
| Summer Cloud Limited | Agriculture & fishing | 2023 |
| Summer Juniper Health Limited | Other services | 2025 |
| Summerbank Properties Limited | Real estate | 1989 |
| Sunflowers (Sandbach) Ltd | Hospitality | 2016 |
| Super Tiger Ltd | Administrative & support | 2006 |
| Supply 2 Trade Bury Ltd | Construction | 2020 |
| Supply 2 Trade Chester Ltd | Wholesale & retail | 2022 |
| Supply 2 Trade Holdings Ltd | Financial services | 2022 |
| Supply 2 Trade Ltd | Wholesale & retail | 2017 |
| Supply 2 Trade Northwich Ltd | Wholesale & retail | 2022 |
| Supply 2 Trade Shrewsbury Ltd | Wholesale & retail | 2022 |
| Supply 2 Trade Telford Ltd | Construction | 2022 |
| Supply Your Vehicle Ltd | Professional & scientific | 2025 |
| Supplyyourtrade Ltd | Administrative & support | 2025 |
| Support for Families Through Birth Litigation Community Interest Company | Information & communication | 2023 |
| Surewave Technology Limited | Professional & scientific | 2010 |
| Survey Builders Ltd | Construction | 2019 |
| Sutton Heating & Renewables Ltd | Construction | 2025 |
| Swallow Studios Limited | Information & communication | 2003 |
| Swift Shoes Limited | Other services | 2012 |
| Symphony Hospitality Limited | Hospitality | 2013 |
| Symphony Outside Ltd | Hospitality | 2023 |
| Synergistic HR Ltd | Professional & scientific | 2018 |
| Synergy Solutions Inc Ltd | Information & communication | 2024 |
| T C Sales Limited | Wholesale & retail | 2006 |
| T Golf Limited | Wholesale & retail | 2003 |
| T J Harrison Coaching Limited | Professional & scientific | 2023 |
| Tafco Limited | Financial services | 2013 |
| TAH Consultancy Limited | Transport & logistics | 2021 |
| TAI Taclus Ltd | Administrative & support | 2023 |
| Tailor Blue Ltd | Wholesale & retail | 2021 |
| Takt UX Ltd | Information & communication | 2023 |
| Talence Ltd | Extraterritorial | 2021 |
| Talentwise MGT Limited | Professional & scientific | 2024 |
| Tall Chimneys Estates Limited | Hospitality | 2023 |
| Tamitbs Limited | Professional & scientific | 2026 |
| Tanc Consultancy UK Limited | Health & social care | 2014 |
| Tangreen Commodities Ltd | Wholesale & retail | 2019 |
| Tanks and Property Ltd | Real estate | 2018 |
| Tanning Quarter (Leek) Ltd | Other services | 2026 |
| Tariffmate Ltd | Information & communication | 2026 |
| Tautliners (UK) Limited | Manufacturing | 2012 |
| Taylor Atkins Limited | Administrative & support | 2003 |
| TCC Limited | Information & communication | 1992 |
| TDH Wholesales Limited | Wholesale & retail | 2022 |
| Tecc Properties Limited | Real estate | 2026 |
| Tecc Short Stays and Lets Ltd | Households | 2026 |
| Technical Laser Ltd | Manufacturing | 2019 |
| Tectoro Consulting Limited | Information & communication | 2015 |
| Tesla Home Improvements Ltd | Construction | 2022 |
| Tessera Sigma Ltd | Information & communication | 2026 |
| Tesseract Security Limited | Information & communication | 2026 |
| Textile Bioengineering and Informatics Society UK Limited | Professional & scientific | 2016 |
| Tfmutya Limited | Health & social care | 2012 |
| That Hair Salon Ltd | Other services | 2024 |
| THE Andrew Connolly Practice Limited | Financial services | 2023 |
| THE Association of Independent Showmen. | Other services | 2014 |