| DIY Surveys Limited | Information & communication | 2020 |
| DIZSALISBURY1 Limited | Other services | 2019 |
| Dizzy Squirrel Limited | Information & communication | 2012 |
| DJ Renovations Ltd | Construction | 2023 |
| DJB Brickwork Limited | Construction | 2014 |
| DJD PM Ltd | Construction | 2022 |
| DJS Pizza Ltd | Hospitality | 2002 |
| DK Solutions Ltd | Professional & scientific | 2012 |
| DKB Creative Limited | Professional & scientific | 2013 |
| DKP Catering Limited | Hospitality | 2011 |
| DL Sales Ltd | Wholesale & retail | 2016 |
| DL Sisters Enterprises Ltd | Wholesale & retail | 2025 |
| DLE Electrical Services Ltd | Construction | 2006 |
| DLG Marine Services Ltd | Construction | 2023 |
| Dmac Liming Ltd | Agriculture & fishing | 2007 |
| DMR Telecom Limited | Information & communication | 2020 |
| DN & E Ltd | Transport & logistics | 2019 |
| DN Property Ventures Ltd | Real estate | 2024 |
| Dndsm Limited | Information & communication | 2011 |
| DNO Technical Ltd | Construction | 2023 |
| Docton Property Services Limited | Construction | 2016 |
| Dogforce UK Ltd | Agriculture & fishing | 2022 |
| Dohatech Healthservice Limited | Administrative & support | 2014 |
| DOL Werdd (Plasdwr) Management Company Limited | Households | 2021 |
| Dolce Paradiso Ltd | Wholesale & retail | 2025 |
| Dolma Salisbury Limited | Real estate | 2025 |
| Dolphin Farms Limited | Agriculture & fishing | 1972 |
| Dolphin Property (Management) Limited | Administrative & support | 1970 |
| Domecast Media Limited | Information & communication | 2026 |
| Domica Ltd | Real estate | 2024 |
| Dominion Road Consulting Ltd | Professional & scientific | 2014 |
| Domoney Woodwork Ltd | Manufacturing | 2017 |
| Donlea Properties LLP | | 2024 |
| Donna’S New Image Limited | Other services | 2018 |
| Donohue Smith & Hartwell Limited | Professional & scientific | 2014 |
| Donovan Long Merchant Services Ltd | Wholesale & retail | 2023 |
| Doodlebug Studios Ltd | Arts & recreation | 2026 |
| Doortechnique Garage Doors Limited | Extraterritorial | 2018 |
| Doozy Cafe Limited | Hospitality | 2014 |
| Doozy Limited | Hospitality | 2014 |
| Doppio Digital Ltd | Information & communication | 2026 |
| Dormer Flats Management Company Limited | Households | 1981 |
| Dorset Flint and Stone Blocks Limited | Manufacturing | 1998 |
| Dorset Generator Hire Ltd | Administrative & support | 2021 |
| Dorset Luxury Toilets Ltd. | Extraterritorial | 2015 |
| Dorset Voice and Data Ltd | Information & communication | 2019 |
| Double Dees B & B Limited | Hospitality | 2025 |
| Doublea Consulting Limited | Information & communication | 2026 |
| Doublecube (DJW) Investments Limited | Professional & scientific | 2017 |
| Doublecube Limited | Professional & scientific | 2008 |
| Douglas & Rose Ltd | Professional & scientific | 2018 |
| Douglas James Training Consultants Limited | Administrative & support | 2000 |
| Douglas Mcleod Framing Ltd | Wholesale & retail | 2020 |
| Dove Green Developments Limited | Construction | 2017 |
| Dove House (East Anglia) Limited | Administrative & support | 2019 |
| Dovetail Aviation Limited | Education | 2013 |
| Downhole Performance Products Limited | Extraterritorial | 2015 |
| Downhurst Court Management Company Limited | Households | 1979 |
| Downing Investments Limited | Financial services | 2025 |
| Downs Syndrome Diamond Foundation Limited | Other services | 1995 |
| Downshift Copy Ltd | Professional & scientific | 2025 |
| Downsview House (Salisbury) Limited | Households | 1982 |
| Downton Cuckoo Fair Limited | Administrative & support | 2003 |
| Downton Scaffolding Ltd | Construction | 2019 |
| Downton Tyre and Autocare Limited | Wholesale & retail | 2014 |
| DPE Design Limited | Professional & scientific | 2008 |
| DR Kate Jenkins Ltd | Health & social care | 2022 |
| DR Loukas Implants & Ceramics Teaching Limited | Education | 2023 |
| DR Paul Sutherland Limited | Health & social care | 2013 |
| DR ROY Kukreja Limited | Health & social care | 2014 |
| DR. Adams Laboratories Ltd | Wholesale & retail | 2019 |
| DR. Blecha Care Limited | Wholesale & retail | 2022 |
| Dragonfly Teas Limited | Professional & scientific | 2005 |
| Drake Accounting Solutions Limited | Professional & scientific | 2008 |
| Draper Heat Limited | Administrative & support | 2014 |
| Draper Property Investments Limited | Real estate | 2020 |
| Draper Ventilation Limited | Manufacturing | 2008 |
| Drashby Limited | Real estate | 2003 |
| Drawbridge Limited | Professional & scientific | 2019 |
| Drifters Coffee House Ltd | Hospitality | 2017 |
| Driftinit Limited | Extraterritorial | 2011 |
| Driftwood Health & Beauty Limited | Wholesale & retail | 2015 |
| Dripclip Limited | Wholesale & retail | 2019 |
| Drive Hart Ltd | Education | 2018 |
| Drive House Consulting Limited | Professional & scientific | 2018 |
| Drive With Yvonne Ltd | Education | 2024 |
| Driven by Lukasz Ltd | Transport & logistics | 2015 |
| Drivers LAB Limited | Education | 2024 |
| DRJ Properties (Southampton) Limited | Real estate | 2003 |
| DRN Hospitality Limited | Hospitality | 2026 |
| Drone 3 Sixty Ltd | Information & communication | 2024 |
| Drone My Business Ltd | Professional & scientific | 2016 |
| Drove Farm LLP | | 2018 |
| Druids Lodge Polo LLP | | 2010 |
| Drvn Apparel Ltd | Manufacturing | 2025 |
| Dryden Management & Consultancy Ltd | Professional & scientific | 2025 |
| Drytress Ltd | Wholesale & retail | 2023 |
| DS Electrical Services (Dses) Ltd | Manufacturing | 2021 |
| Dses Properties Ltd | Real estate | 2024 |
| Dset Ltd | Education | 2020 |