| Donnan Holdings Limited | Financial services | 2019 |
| Donnelly Projex Ltd | Construction | 2026 |
| Donovans.Biz Limited | Information & communication | 2025 |
| Doonaree Holdings Limited | Extraterritorial | 2007 |
| Door and Shutter Services Ltd | Construction | 2024 |
| Doors 4 Yours Ltd | Wholesale & retail | 2022 |
| Doorstep Education Ltd | Education | 2023 |
| Doubletable Limited | Real estate | 1986 |
| Doubletree Medical Limited | Health & social care | 2023 |
| Dove Cleaning and Environmental Services Ltd | Administrative & support | 2011 |
| Dove Domestic Limited | Administrative & support | 2018 |
| Dovetail Planning Limited | Professional & scientific | 2025 |
| Dowell Projects Ltd | Real estate | 2021 |
| Downstage Edge Events Ltd | Professional & scientific | 2022 |
| DP World Freight Forwarding UK Ltd | Transport & logistics | 1990 |
| DPB Courier Services Ltd | Transport & logistics | 2026 |
| DR Bocsa Aesthetic Clinic Ltd | Health & social care | 2022 |
| DR Fitzpatrick Consultancy Ltd | Other services | 2024 |
| DR Gold Ltd | Health & social care | 2016 |
| DR H. Mahdi G.P. Limited | Health & social care | 2013 |
| DR MA Aesthetics Ltd | Health & social care | 2019 |
| DR MA Properties Ltd | Real estate | 2022 |
| DR Sadic Medical Services Ltd | Health & social care | 2023 |
| DR Saima Latif Limited | Health & social care | 2008 |
| DR. Kasia Limited | Health & social care | 2011 |
| Dragon Brokers Limited | Financial services | 2013 |
| Dragon Consultants Limited | Professional & scientific | 2019 |
| Dragon Mortgages Ltd | Financial services | 2013 |
| Dragonsmith 2026 Ltd | Professional & scientific | 2026 |
| Dragonsmith Limited | Professional & scientific | 2020 |
| Drake Street Properties Limited | Real estate | 1963 |
| Dravico Ltd | Wholesale & retail | 2025 |
| Dream Bricks Enterprise Ltd | Wholesale & retail | 2025 |
| Dream Bricks Financial Ltd | Financial services | 2021 |
| Dream Bricks Ltd | Real estate | 2018 |
| Dream Keepers Limited | Wholesale & retail | 2023 |
| Dreamara Limited | Wholesale & retail | 2025 |
| Dreamerss Ltd | Other services | 2022 |
| Dreamyes Ltd | Wholesale & retail | 2024 |
| Drees & Sommer UK Limited | Administrative & support | 1999 |
| Drelite Ltd | Education | 2025 |
| Driti Ltd | Wholesale & retail | 2025 |
| Drive Direct Automotive Ltd | Transport & logistics | 2016 |
| Drive Direct Limited | Transport & logistics | 2014 |
| Drive Direct Logistics Limited | Transport & logistics | 2011 |
| Drive Shine Hand Car Wash (Sale) Ltd | Other services | 2017 |
| DRONE360 Ltd | Professional & scientific | 2015 |
| Drops of GOD Limited | Administrative & support | 2016 |
| Drsp Holdings Limited | Financial services | 2016 |
| Drsp Limited | Financial services | 2011 |
| Dryden Motors Limited | Wholesale & retail | 2009 |
| DS One Architects Limited | Professional & scientific | 2000 |
| DSE Projects Ltd | Other services | 2016 |
| Dsign Interiors Ltd | Wholesale & retail | 2023 |
| DSL Regulatory Limited | Public administration | 2020 |
| DSN Enterprises Ltd | Health & social care | 2020 |
| DSN2 Limited | Real estate | 2023 |
| DSW Financial Limited | Financial services | 2015 |
| DT Laundry Service Ltd | Other services | 2010 |
| DTG Developments (Arkholme) Ltd | Construction | 2026 |
| DTG People Solutions Ltd | Administrative & support | 2025 |
| DTM Installations Ltd | Construction | 2019 |
| DU Developments Limited | Construction | 2016 |
| Ducati Manchester Limited | Wholesale & retail | 2011 |
| Duce Group Limited | Financial services | 2026 |
| Duce Properties Limited | Real estate | 2026 |
| Dunkirk Management Company Limited | Households | 2021 |
| Dunkys Day Nurseries Ltd | Health & social care | 2008 |
| Dutta Property Limited | Real estate | 2023 |
| Dwell Inc Limited | Real estate | 2024 |
| DWL Consulting Ltd | Information & communication | 2017 |
| Dynamic Chiropractic Ltd | Health & social care | 2003 |
| Dynamic Courage Ltd | Wholesale & retail | 2024 |
| Dynamico Systems Limited | Professional & scientific | 2020 |
| DZ Supply Chain Ltd | Administrative & support | 2019 |
| E & I Consulting Limited | Real estate | 2014 |
| E Want Developments Ltd | Construction | 2018 |
| E&L Properties Ltd | Households | 2023 |
| E-Call Connect Limited | Information & communication | 2010 |
| E-Commerce International Ltd | Wholesale & retail | 2025 |
| E-Planet Sales Ltd | Wholesale & retail | 2012 |
| EA Hive Ltd | Information & communication | 2017 |
| EAA Holdings Ltd | Financial services | 2015 |
| Eagle & Young Limited | Information & communication | 2018 |
| Eagleeye Security MCR Ltd | Administrative & support | 2021 |
| Eagleye Productions Limited | Information & communication | 2013 |
| Eamonn O'Rourke Limited | Professional & scientific | 2015 |
| Earlscliffe Court (Bowdon) Management Company Limited | Households | 1986 |
| Early Doors M33 Ltd | Hospitality | 2022 |
| Earnest Assets Ltd | Financial services | 2018 |
| Earnest Holdings Ltd | Real estate | 2019 |
| Earnest Property Investments Ltd | Real estate | 2017 |
| East Bay Solutions Ltd | Information & communication | 2017 |
| East Lancashire EYE Care Services Limited | Health & social care | 2015 |
| East Point Management (Leeds) Ltd | Real estate | 2019 |
| Easy Adventures Ltd | Administrative & support | 2025 |
| EAT Fashion Ltd | Hospitality | 2026 |
| Eatitupdesign Ltd | Professional & scientific | 2017 |
| Eavia Ltd | Professional & scientific | 2020 |
| Eccles Archery Club Limited | Arts & recreation | 2019 |