| Ecclesia App Limited | Information & communication | 2022 |
| Eccleside Management Company Limited | Real estate | 2020 |
| Ecgoing Travel Ltd | Administrative & support | 2016 |
| Eco and Sage Limited | Professional & scientific | 2020 |
| Eco Babe Private Day Nursery Limited | Education | 2021 |
| Eco Life Renew UK Ltd | Wholesale & retail | 2026 |
| Eco Sourcing Hub Ltd | Wholesale & retail | 2023 |
| Eco-Worthy Clean Energy UK Ltd | Wholesale & retail | 2024 |
| Economic Holdings Limited | Financial services | 2008 |
| Economic Property Investments Ltd | Real estate | 1940 |
| Economy GAS Limited | Energy | 1995 |
| Ecorend (NW) Limited Ltd | Construction | 2026 |
| Ecse LLP | | 2015 |
| ECT Instruments Ltd | Manufacturing | 2004 |
| Edbury Daley Limited | Administrative & support | 2004 |
| Edbury Daley Properties Limited | Real estate | 2019 |
| Eden in the Wilde Ltd | Administrative & support | 2025 |
| Edenwood Landscapes Ltd. | Other services | 2013 |
| Edge Cloud Ltd | Information & communication | 2024 |
| Edge Polymers Limited | Water & waste | 2023 |
| Edge Scaffolding Ltd | Construction | 2019 |
| Edge Technologies PVT Ltd | Wholesale & retail | 2025 |
| Edge Waste Management Limited | Water & waste | 2025 |
| Edgemount Property Management Limited | Households | 1979 |
| Edibell Ltd | Manufacturing | 2017 |
| Ediven Limited | Other services | 2026 |
| EDP Associates Limited | Professional & scientific | 2008 |
| EDS Electrical Ltd | Construction | 2023 |
| Edstart Trafford Ltd | Education | 2023 |
| Educate GM Ltd | Administrative & support | 2020 |
| Education Leadership for Professionals Limited | Professional & scientific | 2015 |
| Educational Europe Ltd | Administrative & support | 2021 |
| Educservices Limited | Administrative & support | 2006 |
| Edward Forshaw Ltd | Information & communication | 2012 |
| Edward Reed Recruitment Limited | Administrative & support | 2015 |
| Edwardian Import Ltd | Wholesale & retail | 2025 |
| Edwardian ROW Management Limited | Real estate | 2002 |
| Edwards Innovation Studio Ltd | Professional & scientific | 2026 |
| Edwards of Sale Limited | Wholesale & retail | 1991 |
| Eezup Ltd | Health & social care | 2025 |
| Efam Investments Limited | Professional & scientific | 2022 |
| Efficient-C Limited | Health & social care | 2015 |
| EFH Ltd. | Financial services | 2023 |
| Egerton Court Flats (Davenport) Limited | Households | 1973 |
| Eggintons Catering Ltd | Hospitality | 2023 |
| Ehcr Consulting Ltd | Information & communication | 2018 |
| EIS Consultancy Ltd | Professional & scientific | 2023 |
| Ejay Solutions Limited | Information & communication | 2018 |
| EJJ Solutions Limited | Information & communication | 2025 |
| EL Crabo Grande Games Ltd | Information & communication | 2024 |
| EL Law Ltd | Professional & scientific | 2015 |
| Elbonmill Limited | Real estate | 1972 |
| Elecway Ltd | Construction | 2023 |
| ELEV-8 Business Consultancy Ltd | Professional & scientific | 2024 |
| Elevate Accountancy Solutions Ltd | Professional & scientific | 2024 |
| Elevate MCR Ltd | Professional & scientific | 2024 |
| Elevate Property Relocations Ltd | Hospitality | 2024 |
| Elevate Risk Services Ltd | Financial services | 2016 |
| Eleventrance Ltd | Information & communication | 2026 |
| Elite Care Providers Limited | Administrative & support | 2020 |
| Elite Commercial Management Services Limited | Professional & scientific | 2020 |
| Elite Haven Realty Ltd | Extraterritorial | 2024 |
| Elite Prime Property Ltd | Real estate | 2024 |
| Elite Surfacing & EXC Manchester Ltd | Construction | 2016 |
| ELITE11 Ltd | Education | 2026 |
| Ellei Home Ltd | Wholesale & retail | 2015 |
| Ellerfields Wythenshaw (NO.1) Management Company Limited | Households | 2004 |
| Elliney Hospitality Limited | Hospitality | 2023 |
| Ellis & Belden Partners Ltd | Administrative & support | 2025 |
| Ellis and Sons (Southern) Property Investments Limited | Real estate | 1940 |
| Ellis Pick & PAY Ltd | Wholesale & retail | 2025 |
| ELM Wealth Services Ltd | Administrative & support | 2026 |
| Elma Property Ltd | Real estate | 2022 |
| Elroi Property Services Limited | Real estate | 2025 |
| Elstashock Entertainment and Production Limited | Hospitality | 2025 |
| Elvi Properties Limited | Real estate | 2017 |
| Elwers Ltd | Wholesale & retail | 2021 |
| Embees Kitchen Ltd | Hospitality | 2026 |
| EMC2 Clinical Consultancy Ltd | Information & communication | 2018 |
| Emchol Ltd | Real estate | 2017 |
| Emiex Ltd | Construction | 2021 |
| Emilios Limited | Hospitality | 2024 |
| Emmas Consulting Limited | Professional & scientific | 2024 |
| Emmatarpeyforensic Ltd | Professional & scientific | 2021 |
| Emmaus Catholic Academy Trust | Education | 2019 |
| Empanda Properties Ltd | Real estate | 2019 |
| Empire Joinery (Manchester) Limited | Construction | 2017 |
| Empix Medical Services Limited | Health & social care | 2013 |
| Empower Coaching & Performance Ltd | Education | 2024 |
| Empower Physio and Pilates CIC | Arts & recreation | 2026 |
| Encompass Psychology Ltd | Health & social care | 2019 |
| Endeavour Development Management Limited | Construction | 2021 |
| Enec Limited | Real estate | 2016 |
| Enercool Limited | Professional & scientific | 2025 |
| Engelwood Communications Limited | Professional & scientific | 2023 |
| English - Swedish World Traders Limited | Wholesale & retail | 1946 |
| Enjoycarlife Limited | Wholesale & retail | 2017 |
| Ennerdale Property Services Limited | Real estate | 2000 |
| Entelligence Healthcare CIC | Professional & scientific | 2025 |
| Enthuse Communications Limited | Professional & scientific | 2015 |