| Dbis Manchester Ltd | Professional & scientific | 2024 |
| DBS Environmental Limited | Professional & scientific | 2011 |
| DC Independent Surveyor Ltd | Professional & scientific | 2020 |
| DC38 Ltd | Real estate | 2017 |
| Dcbn - Domestic Cleaning Business Network Limited | Other services | 2021 |
| DCF Electrical Wholesalers Ltd | Wholesale & retail | 2017 |
| DCL Contractors Ltd | Construction | 2025 |
| Dcpt Ltd | Other services | 2011 |
| Ddiscerning Limited | Wholesale & retail | 2018 |
| Dean Health Care Ltd | Other services | 2023 |
| Debt Advice Expert Limited | Other services | 2019 |
| Decoma Limited | Real estate | 2021 |
| Decorative Stone Limited | Construction | 2009 |
| Decsys Limited | Information & communication | 2016 |
| Deen Enterprise (UK) Limited | Hospitality | 2003 |
| Deepmesh Industries Ltd | Financial services | 2025 |
| Defod Ltd | Real estate | 2021 |
| Delafuentecelia Ltd | Health & social care | 2022 |
| Delaheys Holdings Limited | Financial services | 2008 |
| Delaheys Land Investments Limited | Real estate | 1931 |
| Delamere Court Management Company (Crewe) Limited | Households | 2006 |
| Deli Cakes Limited | Hospitality | 2022 |
| Delicea Ltd | Hospitality | 2025 |
| Delicious Bite Limited | Hospitality | 2023 |
| Delicious Chester House Ltd | Hospitality | 2025 |
| Delightchoice Limited | Wholesale & retail | 2018 |
| Delsys Europe Ltd | Professional & scientific | 2014 |
| Deltera Healthtech Ltd | Information & communication | 2022 |
| Demihomes Ltd | Real estate | 2024 |
| Dempa Holdings Ltd | Wholesale & retail | 2019 |
| Dengo Ltd | Health & social care | 2014 |
| Denken Knowledge Limited | Education | 2024 |
| Dennie Charles Ltd | Information & communication | 2019 |
| Denra Production (UK) Limited | Information & communication | 2021 |
| Denstone Architectural Design Ltd | Professional & scientific | 2006 |
| Dequincey Homes Limited | Administrative & support | 2015 |
| Derby Court Limited | Professional & scientific | 1968 |
| Derm Club Ltd | Health & social care | 2023 |
| Derm Studio Ltd | Health & social care | 2024 |
| Dermyl Ltd | Health & social care | 2023 |
| Desford Publishing Ltd | Administrative & support | 2007 |
| Design Port Ltd | Wholesale & retail | 2010 |
| DESIGN@STUDIO17 Ltd | Professional & scientific | 2015 |
| Designkarma Ltd | Information & communication | 2007 |
| Detail Design Engineering Limited | Extraterritorial | 1991 |
| Devonshire House Management (MID) Ltd | Real estate | 2019 |
| Devonshire Properties (Liverpool) Limited | Real estate | 2003 |
| Deyeng Limited | Professional & scientific | 2017 |
| Diagnostic Radiology Ltd | Health & social care | 2010 |
| Diamond Duties Ltd | Construction | 2020 |
| Diamonddstw Ltd | Professional & scientific | 2021 |
| Diazone Computer Services Limited | Information & communication | 2001 |
| Diddibox Events Ltd | Wholesale & retail | 2024 |
| Diets 2 Go Limited | Other services | 2013 |
| Digby Charles Limited | Professional & scientific | 2008 |
| Digi-Group (PDB) Limited | Professional & scientific | 2022 |
| Digica Solutions Limited | Information & communication | 2009 |
| Digital Accounting Specialist Services Limited | Administrative & support | 2024 |
| Digital Unlocked Ltd | Information & communication | 2024 |
| Digitalocta Ltd | Information & communication | 2019 |
| Digitwin AM Limited | Information & communication | 2018 |
| Digiwise Consulting Ltd | Real estate | 2023 |
| Dikak Limited | Real estate | 2024 |
| Dimensions Care Limited | Health & social care | 2019 |
| Dinolandia Ltd | Wholesale & retail | 2025 |
| Diode Technology Ltd | Wholesale & retail | 2025 |
| DIP in and OUT With Lucy C.I.C. | Health & social care | 2024 |
| Direct Car Centre Ltd | Wholesale & retail | 2022 |
| Direct Dryline Solutions Limited | Construction | 2007 |
| Direct Promotions (North West) Limited | Wholesale & retail | 2007 |
| Director Advice Limited | Professional & scientific | 2020 |
| Divine Tech and Solutions Ltd | Administrative & support | 2024 |
| Dixons Heating Services Limited | Manufacturing | 2024 |
| Dixytots Limited | Education | 2021 |
| DJ Moores and Sons Roofing Ltd | Construction | 2026 |
| DJ Plumbing & Heating Limited | Construction | 2003 |
| DJB Hearing Limited | Wholesale & retail | 2012 |
| DK Evans Ltd | Administrative & support | 2013 |
| DKF Trades & Labour Ltd | Administrative & support | 2019 |
| DKP Real Estates Ltd | Real estate | 2024 |
| DLS Assessors Ltd | Financial services | 2014 |
| Dmcl & Associates Ltd | Professional & scientific | 2019 |
| DMG Engineering Solutions Ltd | Professional & scientific | 2011 |
| Dmgoc Limited | Other services | 2024 |
| Dmure Ltd | Wholesale & retail | 2024 |
| DN Sports Arena Ltd | Arts & recreation | 2026 |
| DNS Productions Limited | Information & communication | 2026 |
| DNW Property Group Ltd | Real estate | 2024 |
| DO OR DYE Hair Design Ltd | Other services | 2018 |
| Dobinson Ltd | Information & communication | 2021 |
| Doctor SM Limited | Health & social care | 2016 |
| Docugo Limited | Health & social care | 2022 |
| Dodiddone Ltd | Real estate | 2019 |
| Dolfor Holdings Limited | Construction | 2025 |
| Dollardev Limited | Information & communication | 2013 |
| Dominic Cole Landscape Architects Ltd | Professional & scientific | 2011 |
| Domus Magnus Properties Ltd | Real estate | 2025 |
| Donally Limited | Real estate | 2019 |
| Doni & Co Financial Ltd | Professional & scientific | 2025 |
| Donna E Mclaughlin Ltd | Professional & scientific | 2021 |