| Crackers & Brie Ltd | Hospitality | 2025 |
| Craig Johnson Enterprises Limited | Information & communication | 2006 |
| Cranleigh Design Consultants Limited | Construction | 2004 |
| CRE8 Land and Planning Limited | Professional & scientific | 2021 |
| Creasey Construction Limited | Construction | 2018 |
| Creative Groundworks NW Ltd | Construction | 2018 |
| Credit Circle Limited | Other services | 2021 |
| Creofabrica Limited | Manufacturing | 2013 |
| Crescent Yards Holdings Ltd | Information & communication | 2024 |
| Crispy COD Sale Ltd | Hospitality | 2023 |
| Crofton Commercials Limited | Wholesale & retail | 2019 |
| Croftsbank Developments Limited | Construction | 2015 |
| Croftsbank Estates Ltd | Real estate | 2024 |
| Cross Street Architects Ltd | Professional & scientific | 2019 |
| Crossfit PRP Ltd | Arts & recreation | 2022 |
| Crosslease Ltd | Real estate | 2025 |
| Crossword Recruitment Ltd | Administrative & support | 2021 |
| Crouch Property & Renovation Co. Ltd | Construction | 2025 |
| Crouchley Hall Mews Management Company Limited | Households | 1996 |
| Crown House Management Services Ltd | Administrative & support | 2020 |
| Crownfront Limited | Health & social care | 1978 |
| Crowther PUB Company Limited | Hospitality | 2013 |
| CRS (Nationwide) LLP | | 2007 |
| CRT Flooring Specialists Limited | Construction | 2009 |
| Crunch Bakehouse Limited | Hospitality | 2018 |
| Crux App Limited | Information & communication | 2025 |
| Crystal Gates Events Limited | Administrative & support | 2021 |
| CS and Sons Limited | Administrative & support | 2021 |
| CS Property Consultants Ltd | Professional & scientific | 2017 |
| CT Metal Recycling Limited | Wholesale & retail | 2018 |
| CT Trophies Ltd | Wholesale & retail | 2021 |
| CTP Manchester Limited | Extraterritorial | 2014 |
| Ctrl Point Ltd | Information & communication | 2025 |
| Cubic Facades Holdings Ltd | Financial services | 2024 |
| Cubic Facades Ltd | Construction | 2013 |
| Cucina Italiana (Sale) Ltd | Hospitality | 2026 |
| Cucina MCR Ltd | Hospitality | 2024 |
| Cumberland Tech Solutions Ltd | Information & communication | 2015 |
| Cuming Family Holdings Ltd | Financial services | 2025 |
| CUP & Crumb Limited | Hospitality | 2021 |
| Cups Cake and More Limited | Wholesale & retail | 2023 |
| Curantis Recruitment Ltd | Administrative & support | 2018 |
| Curious Nomads Ltd | Administrative & support | 2018 |
| Curtin Wood Limited | Administrative & support | 2020 |
| Custerian Limited | Professional & scientific | 2006 |
| Cutting Edge Car Details Limited | Wholesale & retail | 2024 |
| Cutting Room (Urmston) Ltd | Other services | 2017 |
| CVM Professional Business Services Ltd | Professional & scientific | 2021 |
| CWY Holdings Limited | Financial services | 2019 |
| CWY Property Ltd | Real estate | 2020 |
| Cyber Regiment Limited | Information & communication | 2024 |
| Cyber Safety Community Interest Company | Information & communication | 2024 |
| D & H (Partnership) Limited | Wholesale & retail | 2006 |
| D a Greenslade & Sons Limited | Construction | 2026 |
| D O T Motorcycles Limited | Administrative & support | 2007 |
| D Swift Building Services Limited | Construction | 2026 |
| D T O'Donoghue Holdings Limited | Financial services | 2026 |
| D&H Partnership Services LLP | | 2020 |
| D&M Premier Properties Ltd | Real estate | 2025 |
| D&R Capital Ltd | Real estate | 2020 |
| D&R Realty Ltd | Real estate | 2026 |
| D&T Golden Property Limited | Construction | 2025 |
| D'Lusso Collection Ltd | Manufacturing | 2018 |
| D'Souza Elements Limited | Construction | 2025 |
| D'Souza Holdings Limited | Financial services | 2025 |
| D-Flex Limited | Professional & scientific | 2006 |
| D-Sky Ltd | Wholesale & retail | 2019 |
| D. Snowball Haulage Limited | Transport & logistics | 2018 |
| D.S Medley: Works Limited | Professional & scientific | 2025 |
| D.W. Motors (Manchester) Limited | Wholesale & retail | 1996 |
| Dabby's Personnel Limited | Public administration | 2025 |
| Dabject Limited | Financial services | 2025 |
| Dabriars Investments | Financial services | 2021 |
| Dacha Group Limited | Wholesale & retail | 2015 |
| Dafoma Foods Limited | Wholesale & retail | 2025 |
| DAJ Holdings Limited | Financial services | 2026 |
| Daliad Holdings Ltd | Financial services | 2020 |
| Daly Brightness Limited | Extraterritorial | 2023 |
| Damian Harrison Ltd | Wholesale & retail | 2019 |
| Damini Bhaker Ltd | Health & social care | 2024 |
| Damp Protection Services Limited | Construction | 2017 |
| Dani Hair Styles Ltd | Other services | 2024 |
| Daniel Evans Consulting Ltd | Information & communication | 2025 |
| Daniel Hill Limited | Construction | 2018 |
| Danielle at NOA Limited | Other services | 2026 |
| Dant Property Group Limited | Real estate | 2015 |
| Dantal Ltd | Real estate | 2016 |
| Daravine Global Limited | Health & social care | 2024 |
| Darcie Talent Limited | Administrative & support | 2025 |
| Darren Fletcher Promotions Limited | Arts & recreation | 2004 |
| Dasmith Limited | Professional & scientific | 2015 |
| Dataranx Consulting Ltd | Information & communication | 2017 |
| Dave & Rose Ltd | Water & waste | 2012 |
| DAVECR8S Expressions Limited | Arts & recreation | 2025 |
| David Forster Copy Limited | Professional & scientific | 2013 |
| David Temperley Radiologist Services Ltd | Health & social care | 2016 |
| David Veress Limited | Health & social care | 2014 |
| Davinell Ltd | Real estate | 2026 |
| Dawsons Surveyors Limited | Professional & scientific | 2014 |
| Dayal Health Limited | Health & social care | 2022 |