| Northshore Classics Limited | Manufacturing | 2018 |
| Nourishbox Limited | Manufacturing | 2025 |
| Nrco Limited | Arts & recreation | 2014 |
| O B Cleaning Services Ltd | Administrative & support | 2015 |
| Oak Games Mobile Ltd | Information & communication | 2015 |
| Oatley Ltd | Real estate | 2022 |
| Obeyesekere Composite Ltd | Professional & scientific | 2025 |
| Old Mill Holiday Park Limited | Hospitality | 2003 |
| Old Pound Close Management Company Limited | Households | 2023 |
| ON the Island Cleaning & Maintenance Ltd | Construction | 2021 |
| On-Time K Taxi Ltd | Transport & logistics | 2023 |
| One SIX Digital Limited | Professional & scientific | 2013 |
| One Wight Health Limited | Health & social care | 2014 |
| Ontogenisis Ltd | Professional & scientific | 2024 |
| Open Minds IOW Ltd | Education | 2019 |
| Oresund Limited | Professional & scientific | 2020 |
| Original Fish Ltd | Professional & scientific | 2014 |
| Orion Investment Corporation Ltd | Extraterritorial | 2025 |
| Orla Property Limited | Real estate | 2025 |
| Osborne Orthopaedics Ltd | Real estate | 2025 |
| Oscar Grant Electrical Ltd | Construction | 2019 |
| OUR Island Builders Ltd | Administrative & support | 2023 |
| P C Pinnacle Construction Ltd | Construction | 2023 |
| P C Security Ltd | Administrative & support | 2015 |
| P S Engineering Limited | Professional & scientific | 2002 |
| Padfield Costs Recovery Management and Advice Limited | Professional & scientific | 2022 |
| Palladian Consulting Limited | Professional & scientific | 2026 |
| Palmers Brook Limited | Real estate | 2017 |
| Panayi Investments Limited | Real estate | 2019 |
| Park Farm Ryde Management Company Limited | Real estate | 2014 |
| Park Way Joinery Ltd | Manufacturing | 1996 |
| Parsons & Colson Consultants Ltd. | Information & communication | 1993 |
| Pear Tree Holidays Ltd | Real estate | 2022 |
| Peekaboo Limited | Professional & scientific | 2012 |
| Pelham Fields Residents Association Limited | Real estate | 1997 |
| Penguin Wight Cleaning Co Ltd | Administrative & support | 2025 |
| Pennells Developments Limited | Construction | 2004 |
| People Media UK Ltd | Arts & recreation | 2021 |
| Pepper Creative Ltd | Other services | 2008 |
| Performance in People Limited | Professional & scientific | 1999 |
| Peter D Harris Roofing Limited | Wholesale & retail | 2005 |
| Phil Hughes Financial Services Ltd | Administrative & support | 2009 |
| Phil Milner Chiropractic Limited | Professional & scientific | 2013 |
| Philander Developments Ltd | Real estate | 2024 |
| Physnew Ltd | Information & communication | 2018 |
| Pickle and Dill Delicatessen Ltd | Hospitality | 2022 |
| Pickle and Dill Ltd | Wholesale & retail | 2021 |
| Pigsty Farm CIC | Agriculture & fishing | 2022 |
| Pinkeye Graphics Limited | Information & communication | 2007 |
| Pinton Aesthetic Ltd | Health & social care | 2026 |
| Pistachio Production Ltd | Arts & recreation | 2021 |
| Ployon Ltd | Professional & scientific | 2018 |
| PMH Trading Limited | Administrative & support | 2010 |
| Poke Isle Ltd | Wholesale & retail | 2025 |
| Pollen Properties Limited | Real estate | 2024 |
| Pollerton Limited | Professional & scientific | 1996 |
| Port 47 Limited | Professional & scientific | 2025 |
| Port ST Helens Limited | Households | 2023 |
| Portinate Limited | Professional & scientific | 2016 |
| Portinscale (Number 7) Limited | Households | 2000 |
| Pottery Court Management Company Limited | Real estate | 2007 |
| Power Device UK Limited | Manufacturing | 1977 |
| Powersure Connections Limited | Manufacturing | 2011 |
| Praetorian Elite Ltd | Administrative & support | 2025 |
| Pre-School @ ST Helens Ltd | Health & social care | 2018 |
| Premier School Sport Coaching Limited | Education | 2011 |
| Prestige (I.W.) Limited | Real estate | 2010 |
| Prices Repair Services Limited | Manufacturing | 2024 |
| Primary Flats Management Company Limited(The) | Professional & scientific | 1981 |
| Prism Strategic Intelligence Limited | Information & communication | 2017 |
| Progressive Projects Ltd | Construction | 2023 |
| Property Broker IOW Limited | Hospitality | 2016 |
| Property Care Management (IOW) Ltd | Real estate | 2019 |
| Property Prudence Ltd | Real estate | 2014 |
| Property Services Isle of Wight Ltd | Administrative & support | 2013 |
| Provocative Human Ltd | Professional & scientific | 2020 |
| Pure Wight Limited | Administrative & support | 2020 |
| Purple Squirrel Solutions Ltd | Construction | 2023 |
| Quarr Abbey Enterprises Limited | Wholesale & retail | 1998 |
| Quench Digital Limited | Professional & scientific | 2008 |
| R & H Fletcher Limited | Hospitality | 2017 |
| R 'N' J Garden Construction Ltd | Administrative & support | 2015 |
| R J Williams & Sons Holdings Limited | Financial services | 2021 |
| Raanu Ltd | Real estate | 2026 |
| Radargen Limited | Manufacturing | 2005 |
| Rafi Services Ltd | Construction | 2022 |
| Rainbow Island IW Community Interest Company | Health & social care | 2022 |
| Rapiertek Limited | Professional & scientific | 2025 |
| RC2017 Management Solutions Ltd | Professional & scientific | 2022 |
| RC2017 Trading Limited | Wholesale & retail | 2017 |
| Rectory Lane Limited | Real estate | 2009 |
| Red Osprey Ltd | Hospitality | 2025 |
| Redwing Construction Limited | Construction | 2012 |
| Reid Bytes Ltd | Information & communication | 2022 |
| Reon Obey Ltd | Manufacturing | 2025 |
| Resolution Copyright Limited | Administrative & support | 1999 |
| Respai Ltd | Information & communication | 2024 |
| Restore-A-Door Ltd | Construction | 2025 |
| Reuse Rehome Relove Limited | Water & waste | 2020 |
| Reveal YOU C.I.C. | Health & social care | 2025 |