| EDM Facilities Management Ltd | Administrative & support | 2014 |
| EDS (SW) Ltd | Professional & scientific | 2019 |
| EDU Wallet Limited | Information & communication | 2016 |
| Eduart C.I.C. | Education | 2024 |
| Education Professional Limited | Extraterritorial | 2014 |
| Edumed Integrative Services Ltd | Education | 2022 |
| Edward Adams Developments Limited | Construction | 2018 |
| Edward Adams Ltd | Construction | 2008 |
| Edwards Stone Masons Ltd | Construction | 2021 |
| Eesha Retails Limited | Wholesale & retail | 2025 |
| Efad Ltd | Public administration | 2025 |
| Effective Interim Dormant Co Ltd. | Professional & scientific | 2026 |
| Efficient Comms Ltd | Information & communication | 2011 |
| Effluent Control (U.K.) Limited | | 1985 |
| Efford Leisure Ltd | Hospitality | 2016 |
| Efirst Software Services Ltd | Information & communication | 2017 |
| Egami RTM Company Ltd | Households | 2020 |
| Egan Rush Holdings Ltd | Construction | 2019 |
| EGE Foods Ltd | Hospitality | 2020 |
| EGI International Education Centre Limited | Professional & scientific | 2024 |
| EGI Sustainable Building Systems Ltd | Wholesale & retail | 2023 |
| Egycare Limited | Health & social care | 2026 |
| EH2024 Limited | Extraterritorial | 2024 |
| EHK Surface Repairs Ltd | Construction | 2017 |
| EHV Print Limited | Manufacturing | 2009 |
| EID Support Limited | Health & social care | 2025 |
| Eidolyn Ltd | Information & communication | 2025 |
| Eight Twenty Property Ltd | Real estate | 2024 |
| Eighteen Holyrood MAN Co Limited | Real estate | 2008 |
| Eighteen ST. Lawrence Road Management Company Limited | Households | 1984 |
| Eilisros Ltd | Professional & scientific | 2025 |
| EJ Creative Solutions Ltd | Information & communication | 2015 |
| Ekogea Contracts Limited | Professional & scientific | 2021 |
| Ekogea Holdings Limited | Financial services | 2020 |
| Ekogea UK Limited | Water & waste | 2017 |
| Ekraj Gallery Limited | Hospitality | 2018 |
| Ekuru Ltd | Information & communication | 2026 |
| EL Capitano (SW) Ltd | Hospitality | 2015 |
| EL Mushy Ltd | Administrative & support | 2024 |
| EL Wills Property Management Ltd | Real estate | 2025 |
| El-Bethel Hands Medicals Ltd | Health & social care | 2023 |
| El-Roi Africa Ltd | Wholesale & retail | 2026 |
| Elain Tide Limited | Hospitality | 2026 |
| Elan Lingerie Ltd | Manufacturing | 2020 |
| Elara OH Ltd | Financial services | 2024 |
| Elatino Limited | Hospitality | 2019 |
| Elaura Ltd | Professional & scientific | 2000 |
| ELB Consultancy Services Ltd | Professional & scientific | 2026 |
| Elburton Garages Limited | Wholesale & retail | 1972 |
| Elburton Heating Ltd | Construction | 2021 |
| Elburton Practice Ltd | Health & social care | 2026 |
| Elburton Village Hall Limited | Arts & recreation | 2004 |
| Elderton MAY Ltd | Other services | 2018 |
| Elecmarine Ltd | Manufacturing | 2026 |
| Electra Marketing Ltd | Administrative & support | 2025 |
| Electrical & Security Ltd | Construction | 2013 |
| Electrical Design South West Limited | Construction | 2008 |
| Electricomm Ltd | Construction | 2010 |
| Electricraft Ltd | Construction | 2025 |
| Electro-Buzz Ltd | Professional & scientific | 2018 |
| Electro-Glaze Ltd | Construction | 2024 |
| Electrotek Solutions Ltd | Information & communication | 2015 |
| Element 24 Ltd | Information & communication | 2019 |
| Element Alusystems Ltd | Construction | 2017 |
| Element Bully's Ltd | Agriculture & fishing | 2015 |
| Elementree Arborists Ltd | Administrative & support | 2026 |
| Elesse Hair & Beauty Salon Ltd. | Other services | 2005 |
| Elevate Awarding Ltd | Education | 2023 |
| Elevate Building Solutions Ltd | Construction | 2017 |
| Elevate Electrical Services (SW) Ltd | Construction | 2022 |
| Elevate Legal (SW) Limited | Professional & scientific | 2025 |
| Eleven Hair Ltd | Other services | 2024 |
| Elezi Trading Ltd | Wholesale & retail | 2025 |
| Elfordleigh Barns Management Limited | Real estate | 2003 |
| Elfordleigh Limited | Hospitality | 1997 |
| Eliot Developments (Cornwall) Limited | Construction | 2015 |
| Eliot Developments (Devon) Ltd | Construction | 2014 |
| Elisa Gonzalez Ltd | Professional & scientific | 2017 |
| Elite Associates (SW) Limited | Extraterritorial | 2015 |
| Elite Automotive Repairs Ltd | Professional & scientific | 2026 |
| Elite Cabs SW Ltd | Transport & logistics | 2024 |
| Elite Cardiac Services Ltd | Health & social care | 2021 |
| Elite Carpentry & Building SW Ltd | Construction | 2022 |
| Elite Complete Property Services Limited | Construction | 2013 |
| Elite Electrical and Solar Limited | Construction | 2024 |
| Elite Electrical Team Limited | Construction | 2007 |
| Elite Heating Limited | Construction | 2018 |
| Elite Key Solutions Ltd | Manufacturing | 2024 |
| Elite Property Estates Limited | Real estate | 2018 |
| Elite Roofing Southwest Ltd | Construction | 2025 |
| Elitehire Consultants Ltd | Administrative & support | 2023 |
| Elixel Ltd. | Information & communication | 2012 |
| Elizabeth Court (Plymouth) Management Company Limited | Construction | 1988 |
| Ellen Aerts Catering Limited | Hospitality | 2022 |
| Ellicott Property Investments Ltd | Real estate | 2022 |
| Ellicott Property Services Ltd | Construction | 2023 |
| Ellie's Haven Trading Company Ltd | Wholesale & retail | 2009 |
| Elliot Driving Academy Limited | Education | 2017 |
| Elliott Developments SW Ltd | Construction | 2020 |
| Elliott Homes (Hayloft) Ltd | Real estate | 2025 |