| SAM YAR UK Ltd | Real estate | 2023 |
| Sam's of Deeping Limited | Wholesale & retail | 2016 |
| SAM123 Ltd | Hospitality | 2024 |
| Samabi Holdings Ltd | Financial services | 2022 |
| Samah's Styles Ltd | Wholesale & retail | 2023 |
| Samaka Care Services Ltd | Health & social care | 2019 |
| Samanna Investments Ltd | Real estate | 2018 |
| Samantha BOW Limited | Construction | 2021 |
| Sambalo Limited | Financial services | 2016 |
| Samchiz Ltd | Health & social care | 2019 |
| Sameday Roof Repair Limited | Construction | 2025 |
| Samir Properties Ltd | Real estate | 2024 |
| Sammy Store Limited | Wholesale & retail | 2021 |
| Samson NE Ltd | Professional & scientific | 2015 |
| Samspek Ltd | Transport & logistics | 2016 |
| Samu Investment Group Limited | Real estate | 2023 |
| Samuel & Garrett Developments Limited | Construction | 2024 |
| Samupita Automotive Support Limited | Wholesale & retail | 2015 |
| Samurai Tech Ltd | Information & communication | 2025 |
| Sanatio Vita Ltd | Professional & scientific | 2018 |
| Sanctuary Stays Ltd | Real estate | 2025 |
| Sanctum 14 Limited | Other services | 2025 |
| Sanctum Health Network Ltd | Health & social care | 2026 |
| Sandalwood Property Investments Limited | Real estate | 2026 |
| Sandbrook Overseas Investments Limited | Professional & scientific | 2007 |
| Sandbrook UK Investments Limited | Professional & scientific | 2007 |
| Sandfray Limited | Wholesale & retail | 2023 |
| Sandgate Belmont Ltd | Real estate | 2024 |
| Sandhams of Rutland Limited | Wholesale & retail | 2023 |
| Sandis Transport Ltd | Transport & logistics | 2018 |
| Sandon Foods Limited | Hospitality | 2005 |
| Sandro Media Ltd | Professional & scientific | 2025 |
| Sandruc Ltd | Transport & logistics | 2017 |
| Sands and Gill Limited | Wholesale & retail | 2010 |
| Sandshire Limited | Real estate | 1963 |
| Sandstone Associates (Bowers) Limited | Professional & scientific | 2005 |
| Sandu Razvan Transport Ltd | Transport & logistics | 2021 |
| Sandy Sports Limited | Wholesale & retail | 2025 |
| Sandy's Care Ltd | Other services | 2016 |
| Sane Health Well Being and Management Limited | Information & communication | 2020 |
| Sanico Limited | Health & social care | 2021 |
| Sanipur UK Ltd | Water & waste | 2019 |
| Sanko Properties Limited | Real estate | 2022 |
| Sanky Alytrans Ltd | Transport & logistics | 2020 |
| Sanlay Possoli Aesthetic Ltd | Other services | 2023 |
| Sanni Enterprise Ltd | Wholesale & retail | 2026 |
| Sans Kitchen Peterborough Limited | Hospitality | 2024 |
| Santa Claus Limited | Information & communication | 1996 |
| Santana's Takeaway Ltd | Hospitality | 2026 |
| Santhosh Properties Limited | Real estate | 2025 |
| Santos Courrier Services Ltd | Transport & logistics | 2025 |
| Santos Transport Solutions Limited | Other services | 2018 |
| Santosparcel.Uk. Ltd | Transport & logistics | 2024 |
| Sanvo UK Limited | Wholesale & retail | 2026 |
| Sany Properties Ltd | Real estate | 2016 |
| Sanzak Ltd | Professional & scientific | 2022 |
| SAP Logistics and Transport Solutions Ltd | Transport & logistics | 2018 |
| Sapele Foods UK Ltd | Wholesale & retail | 2025 |
| Saphya Ltd | Administrative & support | 2019 |
| Sapin Properties Ltd | Construction | 2015 |
| Sapiolo Limited | Manufacturing | 2025 |
| Saplatya Ltd | Transport & logistics | 2026 |
| Sapphire Heating Services Ltd | Construction | 2021 |
| Sapri Transport Ltd | Transport & logistics | 2024 |
| Sar-Max Ltd | Transport & logistics | 2022 |
| Sarah Laird Ltd | Professional & scientific | 2012 |
| Sarah Payne Studios Ltd | Wholesale & retail | 2020 |
| Sarana Investments Ltd | Real estate | 2017 |
| Saraz Ltd | Wholesale & retail | 2025 |
| Sarex Ltd | Transport & logistics | 2023 |
| Sarfaraz Logistics Ltd | Transport & logistics | 2024 |
| Sarim Ahmed Limited | Wholesale & retail | 2019 |
| Saris Outdoors Ltd | Construction | 2022 |
| Sarkar Motors Ltd | Wholesale & retail | 2024 |
| Sarmonas Ltd | Administrative & support | 2016 |
| Sarolga Ltd | Hospitality | 2026 |
| Sarro Property Investments Ltd | Real estate | 2007 |
| SAS Engineering Limited | Professional & scientific | 1996 |
| Sasak Transport Ltd | Administrative & support | 2017 |
| Sasta Bazaar Peterborough Limited | Wholesale & retail | 2025 |
| Satara Sound Limited | Real estate | 2021 |
| Sataxi Limited | Transport & logistics | 2025 |
| Saterra Financial Limited | Other services | 2021 |
| Satin & Stitch Ltd | Wholesale & retail | 2025 |
| Satkar Ltd | Hospitality | 2022 |
| Satnam Homes Ltd | Real estate | 2020 |
| Satnam Transauto Ltd | Transport & logistics | 2019 |
| Satnav Repairs Ltd | Manufacturing | 2024 |
| Satra Advisory Ltd | Professional & scientific | 2022 |
| Saturn Residential Limited | Real estate | 2020 |
| Saule Properties Ltd | Construction | 2015 |
| Saulws Ltd | Transport & logistics | 2022 |
| Saunders-Axam & Sons Ltd | Financial services | 2020 |
| SAV Fasulo Services Limited | Manufacturing | 2000 |
| SAV M Services Limited | Transport & logistics | 2024 |
| Savage Property Services Limited | Other services | 2022 |
| Savani Ltd. | Transport & logistics | 2016 |
| Save Autos Ltd | Wholesale & retail | 2023 |
| Savile ROW Tailoring Limited | Wholesale & retail | 2020 |
| Saville Road Motors (Cambs) Ltd | Wholesale & retail | 2018 |