| Savns Care Group Ltd | Health & social care | 2025 |
| Savolex Limited | Wholesale & retail | 2014 |
| Savorae Ltd | Wholesale & retail | 2026 |
| Savvi Travel Oundle Ltd | Administrative & support | 2022 |
| Savvix Ltd | Wholesale & retail | 2025 |
| Savvy Creative Ltd | Other services | 2021 |
| Sawtry Media Limited | Information & communication | 2004 |
| Saxon Works Limited | Real estate | 2017 |
| Sayed's Peterborough Ltd | Hospitality | 2022 |
| Sayeds Fresh Foods Ltd | Hospitality | 2026 |
| SB Active Ltd | Other services | 2019 |
| SB Associates Personal Consultancy Limited | Professional & scientific | 2019 |
| SB Cars and Commercials Peterborough Ltd | Wholesale & retail | 2021 |
| SB Decorations UK Limited | Construction | 2013 |
| SB Retail Mart Limited | Wholesale & retail | 2025 |
| SB Services Educational Ltd | Professional & scientific | 2010 |
| SB Welding and Fabrication Services Ltd | Manufacturing | 2020 |
| Sbac Business Services Limited | Administrative & support | 2023 |
| Sbfa Investments Ltd | Real estate | 2021 |
| SBL Invest Ltd | Financial services | 2025 |
| Sbns Engineering Ltd | Manufacturing | 2021 |
| SBP Trade Ltd | Information & communication | 2015 |
| SBS Developments (SEC) Ltd | Construction | 2018 |
| SBS Property Management Limited | Real estate | 2025 |
| Sbsk Consultants Limited | Health & social care | 2012 |
| SC Electrical Contracting Ltd | Construction | 2022 |
| SC Heating Care Ltd | Construction | 2017 |
| SC Maintenance + Facilities Limited | Construction | 1996 |
| Scale DNA Ltd | Professional & scientific | 2020 |
| Scales Legal Services Limited | Professional & scientific | 2023 |
| Scampton Residents Company Limited | Households | 2001 |
| Scarcha Holdings Ltd | Hospitality | 2023 |
| Scarlett Associates Limited | Professional & scientific | 2018 |
| SCD HR Ltd | Administrative & support | 2022 |
| Sce-Buz Ltd | Transport & logistics | 2023 |
| Scenic Cleaning Service Ltd | Administrative & support | 2018 |
| Sceptre Promotions Limited | Information & communication | 2009 |
| Schnell Holdings Ltd | Real estate | 2024 |
| Schola Regia Trading Limited | Extraterritorial | 1994 |
| School of K9 Ltd | Other services | 2024 |
| School Road Management Limited | Real estate | 2003 |
| Schoolblazer Limited | Wholesale & retail | 2004 |
| Schools Go Skiing Ltd | Administrative & support | 2023 |
| Schools Go Surfing Limited | Administrative & support | 2017 |
| Schools Publishing Ltd | Information & communication | 1999 |
| Schoolus Ltd | Education | 2019 |
| Schuchmann LLP | | 2016 |
| Scichem Limited | Extraterritorial | 2021 |
| Scientia Wellbeing Ltd | Health & social care | 2024 |
| Scientific Dynamics Limited | Professional & scientific | 2013 |
| Scientific Word Limited | Wholesale & retail | 1990 |
| Sciopolis Ltd | Construction | 2022 |
| SCL Car Detailing Ltd | Wholesale & retail | 2017 |
| SCM Fire & Safety Ltd | Administrative & support | 2025 |
| Scmn Care Ltd | Health & social care | 2024 |
| Scope Motors Limited | Wholesale & retail | 2025 |
| Scoretrust Technology Limited | Information & communication | 2025 |
| Scorpion Creations Limited | Real estate | 2025 |
| Scott Gibbin (Peterborough) Limited | Real estate | 2008 |
| Scott Morris & Co Ltd | Real estate | 2022 |
| Scott Porter Financial Limited | Financial services | 2008 |
| Scott Thomas Properties Ltd | Real estate | 2017 |
| Scott Whight Limited | Professional & scientific | 2007 |
| Scotts Lane Management Company Limited | Households | 2021 |
| Scrap Car Solution Limited | Wholesale & retail | 2024 |
| Screaming Pixels Ltd | Other services | 2009 |
| Scribal Management Services Ltd | Other services | 2017 |
| Script Design UK Ltd | Manufacturing | 2024 |
| Scrolllearn Ltd | Information & communication | 2026 |
| Scrum Consulting Ltd | Information & communication | 2021 |
| Sculthorp Consulting Services Limited | Information & communication | 2014 |
| SD Window Cleaning Ltd | Administrative & support | 2025 |
| SDA Fleet Services Ltd | Wholesale & retail | 2021 |
| SDC Logistics Ltd | Transport & logistics | 2021 |
| SDD Global Property Limited | Professional & scientific | 2013 |
| SDJ Sports 2012 Limited | Professional & scientific | 2012 |
| SDJ Sports Limited | Wholesale & retail | 2012 |
| Sdlt Logistic Ltd | Transport & logistics | 2021 |
| SDR Transport Services Ltd | Transport & logistics | 2019 |
| Sdtr Consultancy Services Ltd | Professional & scientific | 2022 |
| SE Surveys Limited | Construction | 2020 |
| Sea Consulting Engineers Limited | Professional & scientific | 2020 |
| Sea Global Holdings Ltd | Financial services | 2026 |
| Sea Technology OIL Refining Mining & Energy Limited | Mining & quarrying | 2024 |
| Seabrook Build Limited | Construction | 2023 |
| Seabrook Design Limited | Professional & scientific | 2022 |
| Seabrook Planning Consultants Limited | Professional & scientific | 2024 |
| Seaford Group Ltd | Hospitality | 2025 |
| Seagull Environment Limited | Manufacturing | 2025 |
| Seal Healthcare Services Ltd | Health & social care | 2022 |
| Seal the Deal Travel Ltd | Administrative & support | 2026 |
| Sealand Residents Company Limited | Households | 2002 |
| Sean Gooding Horseboxes Limited | Wholesale & retail | 2005 |
| Sean Johnson Design Ltd. | Professional & scientific | 2016 |
| Seas END Development Limited | Construction | 2021 |
| Seaside Bidco Limited | Financial services | 2025 |
| Seaside Topco Limited | Financial services | 2025 |
| Sebrok Construction Ltd | Construction | 2015 |
| Seche Limited | Transport & logistics | 2017 |
| Seckloe House Management Ltd | Real estate | 2014 |