| SAA Accountancy Limited | Professional & scientific | 2012 |
| Saads Bite Box Ltd | Hospitality | 2024 |
| Saafi Trading Limited | Wholesale & retail | 2022 |
| Saara & Hadia Limited | Hospitality | 2022 |
| Saarp Restaurants UK Limited | Hospitality | 2025 |
| Saasa Ltd | Real estate | 2025 |
| Saasix Solutions Limited | Administrative & support | 2024 |
| Saax Property Investments Ltd | Real estate | 2020 |
| SAB 2 Trans Ltd | Transport & logistics | 2016 |
| Sabanu Care Ltd | Health & social care | 2020 |
| Sabanu Cleaning Service Ltd | Administrative & support | 2021 |
| Sabanu Recruitment Agency Ltd | Administrative & support | 2022 |
| Sabe Property Developments Limited | Real estate | 2022 |
| Sabir Investments Ltd | Real estate | 2021 |
| Sabos Holdings Limited | Financial services | 2013 |
| Sabre One Investments Limited | Real estate | 2020 |
| Sabre Sound Ltd | Information & communication | 2018 |
| Sacramentum Limited | Professional & scientific | 2022 |
| Sacred Black Tattoo Ltd | Other services | 2017 |
| Sacred Design Solutions Ltd | Professional & scientific | 2022 |
| Sadar Investments Ltd | Construction | 2022 |
| Saddington-Nash Building Restoration Ltd | Construction | 2024 |
| Saddique Properties Limited | Real estate | 2023 |
| Sadina Ltd | Hospitality | 2024 |
| Sadiq Property Group Ltd | Construction | 2021 |
| Sadler Group Ltd | Construction | 1980 |
| Saes Engineering Ltd | Professional & scientific | 2022 |
| SAF Estate Cambs Ltd | Real estate | 2025 |
| SAF Healthcare Ltd | Health & social care | 2013 |
| Safagrow Limited | Manufacturing | 2010 |
| Safapac (Cambridge) Limited | Professional & scientific | 2007 |
| Safapac Holdings Limited | Financial services | 2012 |
| Safapac Limited | Manufacturing | 1996 |
| Safe GAS Connections Ltd | Construction | 2021 |
| Safe Haven Pathways Counselling Ltd | Administrative & support | 2025 |
| Safe Local Trades.Com Limited | Other services | 2004 |
| Safe Supermarket Limited | Wholesale & retail | 2012 |
| Safe-Tec Training Services Limited | Education | 2002 |
| Safeguard Glazing Installations Limited | Construction | 2025 |
| Safeguard Glazing Supplies Limited | Manufacturing | 1995 |
| Safeguard Hire Services Limited | Wholesale & retail | 1996 |
| Safeguard Motors Ltd | Wholesale & retail | 2019 |
| Safeguarding for ALL Ltd | Education | 2024 |
| Safety Experts Ltd | Information & communication | 2026 |
| Safety Remotely Limited | Public administration | 2015 |
| Safi Investments Ltd | Real estate | 2022 |
| Safikleen Solutions Limited | Administrative & support | 2025 |
| Sagaa Private Limited | Wholesale & retail | 2025 |
| Sagaa Retail Ltd | Wholesale & retail | 2021 |
| Sagaseta Assets Limited | Administrative & support | 2022 |
| Sagaseta Group Holdings Ltd | Transport & logistics | 2020 |
| Sagaseta Investments Limited | Financial services | 2022 |
| Sageer Holdings Ltd | Real estate | 2020 |
| Saghir Photography Ltd | Professional & scientific | 2022 |
| SAH Education Consultant Ltd | Professional & scientific | 2024 |
| Sahaj Management Limited | Real estate | 2019 |
| Sahar Aesthetics Limited | Other services | 2024 |
| Sahara Community Care Services Limited | Health & social care | 2005 |
| Sahlana Limited | Wholesale & retail | 2025 |
| Sahnkha Ltd | Other services | 2018 |
| SAI Lakshmi Trading Ltd | Wholesale & retail | 2018 |
| SAI Siva Ltd | Wholesale & retail | 2019 |
| SAI South West Limited | Real estate | 2023 |
| Sai's Mini Market Ltd | Wholesale & retail | 2022 |
| Saiagri Ltd | Information & communication | 2019 |
| Saif Investment Properties Limited | Real estate | 2025 |
| Saiire Ltd | Wholesale & retail | 2025 |
| Sailor Fishmongers Limited | Wholesale & retail | 2025 |
| Sainalytics Ltd | Administrative & support | 2017 |
| Saindhavi Limited | Health & social care | 2023 |
| Saint Barx Limited | Real estate | 2019 |
| Saiserv Ltd | Information & communication | 2021 |
| Saith Assets Ltd | Real estate | 2025 |
| SAJ Construction & Developments Limited | Construction | 2018 |
| SAJ Developments (Whittlesey) Ltd | Construction | 2021 |
| SAJ Properties (Peterborough) Ltd | Real estate | 2018 |
| SAJ Travels Ltd | Transport & logistics | 2022 |
| Sakeni Limited | Real estate | 2025 |
| Sakina Health Care Ltd | Financial services | 2011 |
| Sakinaz Limited | Wholesale & retail | 2026 |
| Saku Skincare Ltd | Wholesale & retail | 2025 |
| Saku Superstore Ltd | Wholesale & retail | 2024 |
| Sal&Was Properties Ltd | Real estate | 2024 |
| Salaam Radio Ltd | Information & communication | 2014 |
| Sales Training Cambridgeshire Ltd | Professional & scientific | 2014 |
| Salford Collage Ltd | Professional & scientific | 2022 |
| Salim Holiday Limited | Real estate | 2024 |
| Salimia Limited | Real estate | 2025 |
| Sallows Ltd | Real estate | 2023 |
| Salls Threading Ltd | Other services | 2023 |
| Salman Investments Ltd | Real estate | 2026 |
| Salmon Topco Limited | Financial services | 2022 |
| Salvarit Properties Ltd | Real estate | 2025 |
| SAM and MUB Ltd | Wholesale & retail | 2023 |
| SAM Control Ltd | Information & communication | 2022 |
| SAM Cuisines Ltd | Hospitality | 2024 |
| SAM Daulton Limited | Information & communication | 2021 |
| SAM Harper Interiors Limited | Wholesale & retail | 2018 |
| SAM Recovery Ltd | Wholesale & retail | 2026 |
| SAM Spencer Investments Ltd | Households | 2017 |