| Orange Copper Bathrooms Ltd | Construction | 2025 |
| Ottaway Property Investments Limited | Real estate | 2023 |
| Owind Limited | Construction | 2026 |
| P Grandison Funeral Directors Limited | Other services | 2013 |
| Party Gifts Ltd | Wholesale & retail | 2019 |
| Pathways for Success Limited | Other services | 2004 |
| Pearl Property Scotland Limited | Real estate | 2019 |
| Pearson Donaldson Properties Limited | Construction | 1997 |
| Peebles and District Citizens Advice Bureau | Other services | 2011 |
| Peebles Auctions Limited | Wholesale & retail | 2019 |
| Peebles Community Trust | Other services | 2012 |
| Peebles Golf Club Limited | Arts & recreation | 1991 |
| Peebles Mini Mart Ltd | Wholesale & retail | 2025 |
| Peebles Rugby Limited | Hospitality | 2018 |
| Peebles Steak Ltd | Hospitality | 2024 |
| Peerless Scientific Ltd | Professional & scientific | 2019 |
| Pencil Press Ltd | Information & communication | 2022 |
| Perceptive Action C.I.C. | Health & social care | 2014 |
| Persona in Progress Limited | Professional & scientific | 2018 |
| PH2O Limited | Construction | 2006 |
| Pinstripe Consultancy Limited | Administrative & support | 2003 |
| Pinstripe Personnel (U.K.) Limited | Administrative & support | 2003 |
| PL5 Solutions Ltd | Wholesale & retail | 2023 |
| PLS Medical Limited | Wholesale & retail | 2003 |
| Polare AI Limited | Information & communication | 2023 |
| Polare Research Limited | Information & communication | 2001 |
| Powrie Ward Ltd. | Hospitality | 2017 |
| Prana BJJ Ltd | Arts & recreation | 2021 |
| Prana Fitness CIC | Other services | 2024 |
| Profit Champions Limited | Administrative & support | 2020 |
| Ptarmigan Project Solutions Ltd | Professional & scientific | 2026 |
| Quercus Garden Plants Limited | Agriculture & fishing | 2003 |
| R a Walter Plumbing & Heating Engineers Ltd. | Construction | 2018 |
| R Books Limited | Professional & scientific | 2019 |
| R. Brockie (Contracting) Limited | Agriculture & fishing | 1972 |
| Rachel Hayward Therapy Ltd | Health & social care | 2018 |
| Raeburn and Campbell Ltd | Administrative & support | 2022 |
| Raising Angel Finance Limited | Financial services | 2017 |
| Rathbone Restaurants Limited | Hospitality | 2007 |
| RAW Wood Construction Ltd | Construction | 2025 |
| RCR Industrial Ltd | Real estate | 2015 |
| REACT2 Ltd | Information & communication | 1995 |
| Red Circle Locksmiths Ltd | Other services | 2017 |
| Regal Bathrooms Peebles Ltd | Wholesale & retail | 2025 |
| Remedial Therapies Ltd | Other services | 2018 |
| RFB Groundworks Ltd | Construction | 2025 |
| Rhodes-Coenen Property Limited | Real estate | 2019 |
| RNR Pilates Limited | Arts & recreation | 2025 |
| Robert Laidlaw & Sons Limited | Manufacturing | 1948 |
| Robertson's Plastering & Decorating Ltd | Construction | 2024 |
| Rose Heart Apothecary Ltd | Wholesale & retail | 2025 |
| Roundhouse Letting Ltd. | Real estate | 2000 |
| Rsemps Consult Ltd | Professional & scientific | 2025 |
| RTA Law LLP | | 2011 |
| Rugbystore Limited | Wholesale & retail | 2020 |
| S Bain Properties Limited | Real estate | 2020 |
| S. Overland Limited | Hospitality | 2016 |
| S3 Construction Scotland Ltd | Administrative & support | 2025 |
| Saltire Fire & Security Ltd | Administrative & support | 2019 |
| Saltire Property Investments Limited | Real estate | 2000 |
| Satellite Consultancy Limited | Professional & scientific | 2010 |
| School Clover Peebles CIC | Education | 2023 |
| Scotai Technology Solutions Ltd | Information & communication | 2026 |
| Scotia Hotel Consultants LLP | | 2013 |
| Scotsdale Finance Ltd. | Administrative & support | 2014 |
| Scott Garcia Rent to Rent Limited | Real estate | 2024 |
| Scott Motors Group Limited | Wholesale & retail | 2022 |
| Searcher Music Group Ltd | Information & communication | 2025 |
| Shire Stove and Chimney Services Ltd | Administrative & support | 2020 |
| Simple AI Ltd | Professional & scientific | 2025 |
| Siriusdawn Limited | Financial services | 1997 |
| Solas for Nature Ltd | Professional & scientific | 2023 |
| Sovereign Enterprise Holdings Ltd | Financial services | 2026 |
| Sportswork Europe Ltd. | Professional & scientific | 2013 |
| Sposa Limited | Information & communication | 2026 |
| Stag and Pineapple Properties Limited | Real estate | 2022 |
| Stanley Brash Construction Ltd. | Construction | 2012 |
| Sterling Prize Group Ltd | Wholesale & retail | 2026 |
| Steven Balmbra Ltd | Wholesale & retail | 2024 |
| Stobo Castle Health Spa Limited | Hospitality | 1986 |
| Stobo Residents Action Group Limited | Agriculture & fishing | 2024 |
| Stobohope Farms | | 1993 |
| Sylvestris Holdings Ltd | Agriculture & fishing | 2025 |
| T Renwick (Kailzie) | | 1985 |
| T. Renwick, Traquair Knowe | | 1987 |
| Tait and Mapp Roofing Ltd | Construction | 2022 |
| Talia Holdings Ltd | Real estate | 2023 |
| Tartan Pony Ltd | Information & communication | 2020 |
| Terrier School Ltd | Education | 2026 |
| Tetra Acoustics Limited | Arts & recreation | 2006 |
| THE Cademuir Clinic Ltd | Health & social care | 2021 |
| THE Dispensary Peebles Ltd | Wholesale & retail | 2022 |
| THE Farm Environment Limited | Professional & scientific | 2009 |
| THE Fidgit Limited Liability Partnership | | 2008 |
| THE Glentress Hotel Limited | Hospitality | 2019 |
| THE Independent Publishing House Ltd | Information & communication | 2015 |
| THE Nifty Harp Project C.I.C. | Manufacturing | 2018 |
| THE Perfect Fit Childrenswear Limited | Wholesale & retail | 2020 |
| THE Perfect Style Ladieswear Limited | Wholesale & retail | 2025 |
| THE Scottish School of Harp Making CIC | Education | 2025 |