| Servicetec Ltd | Information & communication | 2021 |
| Servio Support Services Ltd | Administrative & support | 2024 |
| Servitio Consulting Ltd | Administrative & support | 2026 |
| Seso Medical Ltd | Health & social care | 2021 |
| SET Media Limited | Professional & scientific | 2016 |
| Sethi Saab Ltd | Wholesale & retail | 2025 |
| Seven Nexus Creative Studio Ltd | Manufacturing | 2025 |
| Seven Nexus Heritage Ltd | Wholesale & retail | 2025 |
| Seven Nexus Prime Ltd | Financial services | 2025 |
| SEVEN6 Design Ltd | Professional & scientific | 2025 |
| Sevenpointfive Logistics Ltd | Transport & logistics | 2026 |
| Sewefficient Limited | Manufacturing | 2011 |
| Sewsafe Products Limited | Administrative & support | 1997 |
| Seyok Ultimate Limited | Wholesale & retail | 2019 |
| SF Liverpool Ltd | Manufacturing | 2023 |
| SG Security Ltd | Administrative & support | 2026 |
| Sgass Ltd | Professional & scientific | 2010 |
| SGB Consultancy Services Ltd | Professional & scientific | 2024 |
| SH Capital Holdings Limited | Real estate | 2020 |
| SH Executive Motors Limited | Wholesale & retail | 2026 |
| SH Fashion Limited | Wholesale & retail | 2026 |
| SH French Developments Limited | Construction | 2007 |
| SHA Therapy Clinic Limited | Transport & logistics | 2024 |
| Shaadi Ltd | Hospitality | 2018 |
| Shaan Store Ltd | Wholesale & retail | 2025 |
| Shabir Hussain 504 Logistics Limited | Transport & logistics | 2025 |
| Shack 27 Limited | Hospitality | 2023 |
| Shadi Solutions Ltd | Information & communication | 2018 |
| Shadmore Investments Ltd | Real estate | 2026 |
| Shah Group Holdings Limited | Real estate | 2023 |
| Shah Shah Traders Limited | Wholesale & retail | 2024 |
| Shah Travel Oldham Limited | Administrative & support | 2022 |
| Shahara Collection Ltd | Wholesale & retail | 2026 |
| Shahbaaz Curry Cottage Limited | Hospitality | 2011 |
| Shahbaz Limited | Wholesale & retail | 2025 |
| Shaheen Trader's Limited | Wholesale & retail | 2026 |
| Shahi Foods Preston Limited | Hospitality | 2022 |
| Shahid Group of Resources Ltd | Information & communication | 2021 |
| Shahid Hussain Enterprises Ltd | Real estate | 2020 |
| Shahmh Limited | Real estate | 2021 |
| Shahzad Dilbar Ltd | Wholesale & retail | 2025 |
| Shaixon Ltd | Wholesale & retail | 2026 |
| Shaiz Ltd | Wholesale & retail | 2018 |
| Shaks Properties Limited | Real estate | 2025 |
| Shaligram Properties Ltd | Real estate | 2020 |
| Shalimar Uppermill Ltd | Hospitality | 2005 |
| Shamas Trading Company Limited | Wholesale & retail | 2018 |
| Shamim Couriers Services Limited | Transport & logistics | 2026 |
| Shamshad Begum Ltd | Wholesale & retail | 2025 |
| Shaney 5 Ltd | Real estate | 2024 |
| Shannon Court Care Home Limited | Health & social care | 2017 |
| Shannoony Ltd | Wholesale & retail | 2023 |
| Shape North Ltd | Education | 2022 |
| Sharbazher Convenience Store Ltd | Wholesale & retail | 2026 |
| Sharebrand Limited | Professional & scientific | 2009 |
| Shared Health Foundation C.I.C. | Health & social care | 2017 |
| Shared Home Properties Ltd | Real estate | 2023 |
| Sharia Labs Ltd | Professional & scientific | 2025 |
| Sharif International Dealer (SID) Limited | Wholesale & retail | 2025 |
| Sharon Lewis Communications & CSR Ltd | Information & communication | 2017 |
| Sharon's Fruit and VEG Limited | Wholesale & retail | 2019 |
| Sharp Electrical Oldham Limited | Construction | 2014 |
| Shashaun Limited | Health & social care | 2013 |
| Shaujhat Additive Manufacturing Limited | Manufacturing | 2026 |
| Shaun Needham Limited | Professional & scientific | 2022 |
| Shauna Supported Living Services Limited | Health & social care | 2021 |
| Shavez Properties UK Ltd | Real estate | 2019 |
| Shaw & Crompton Meals on Wheels CIC | Manufacturing | 2025 |
| Shaw Carpet Centre Limited | Wholesale & retail | 1993 |
| Shaw Direct Ltd | Wholesale & retail | 2022 |
| Shaw Hall Finance Ltd | Professional & scientific | 2020 |
| Shaw Hall Residents Association Limited | Households | 2002 |
| Shaw Hand Car Wash Ltd | Administrative & support | 2023 |
| Shaw Kebab House Ltd | Hospitality | 2020 |
| Shaw Local Limited | Wholesale & retail | 2026 |
| Shaw Mini Market Ltd | Wholesale & retail | 2025 |
| Shaw MOT Centre Limited | Wholesale & retail | 2008 |
| Shaw Motor Group Ltd | Wholesale & retail | 2023 |
| Shaw Property Capital Ltd | Real estate | 2026 |
| Shaw Skips Limited | Water & waste | 2017 |
| Shaw Swift Logistics Ltd | Transport & logistics | 2025 |
| Shawaal Traders Ltd | Wholesale & retail | 2026 |
| Shawclough Properties Ltd | Real estate | 2025 |
| Shays Assets Limited | Financial services | 2014 |
| Shazam Flooring Ltd | Construction | 2021 |
| Shazoptix Ltd | Health & social care | 2011 |
| SHE Wore IT Studio Ltd | Wholesale & retail | 2020 |
| Shear Hair and Beauty Ltd | Other services | 2025 |
| Shearings Holdings Limited | Financial services | 2024 |
| Shearings Investments Limited | Financial services | 2025 |
| Sheba Manchester Limited | Real estate | 2010 |
| Shedmaster UK Limited | Construction | 2012 |
| Sheen's Beauty Studio Limited | Other services | 2024 |
| Sheene and Shaw Developments Limited | Construction | 2017 |
| Sheer Property Group Ltd | Real estate | 2023 |
| Sheerazi Limited | Hospitality | 2020 |
| Sheet Piling & Welding Services Ltd | Professional & scientific | 2017 |
| Sheik & Noorjahan Group Limited | Financial services | 2025 |
| Sheik Law Consultancy Limited | Professional & scientific | 2025 |
| Sheikh's Kitchen Limited | Hospitality | 2025 |