| Salhouse Property Development Limited | Construction | 2024 |
| Salhouse Road Fast Fit Centre Limited | Wholesale & retail | 1999 |
| Salhouse Stag Limited | Hospitality | 2025 |
| Salire Limited | Wholesale & retail | 2017 |
| Salix Caprea Limited | Financial services | 2023 |
| Salle Developments Limited | Construction | 2012 |
| Salle Farms Company | Agriculture & fishing | 1973 |
| Salt Construction (East Anglia) Limited | Construction | 2023 |
| Salt Event Hire Ltd | Administrative & support | 2024 |
| Salt Shore Limited | Hospitality | 2026 |
| Saltcarr Farms Limited | Agriculture & fishing | 2008 |
| Saltmarsh Marine Ltd | Manufacturing | 2023 |
| Saltstore Limited | Wholesale & retail | 2011 |
| Saltwater Recruitment Limited | Administrative & support | 2018 |
| Saltwater Solutions Ltd | Manufacturing | 2010 |
| Saltwrights Ltd | Manufacturing | 2021 |
| Salus Capital Ltd | Financial services | 2022 |
| Salvin Court Residents Association Limited | Real estate | 2006 |
| SAM Barber Norwich Ltd | Other services | 2026 |
| SAM Bone Creative & Copy Limited | Professional & scientific | 2017 |
| SAM Chapman Limited | Professional & scientific | 2023 |
| SAM Food Norwich Ltd | Hospitality | 2019 |
| SAM Goodwin Consultancy Limited | Professional & scientific | 2011 |
| SAM Howell Coaching Ltd | Professional & scientific | 2021 |
| SAM Moon Facilitation Ltd | Professional & scientific | 2025 |
| SAM Neser Racing Limited | Arts & recreation | 2024 |
| SAM UK Property Holdings Ltd | Financial services | 2020 |
| SAM Watkinson Strategy Ltd | Professional & scientific | 2024 |
| Samalf Ltd | Professional & scientific | 2014 |
| Samantha Hawkins Consultancy Ltd | Administrative & support | 2023 |
| Samantha Mckay Garden Design Limited | Administrative & support | 2011 |
| Samfancy Group Ltd | Information & communication | 2022 |
| Samgeo Healthcare Ltd | Health & social care | 2018 |
| Sami's Takeaway Ltd | Hospitality | 2018 |
| Samiya Caterers Limited | Hospitality | 2018 |
| Samkin Limited | Professional & scientific | 1992 |
| Sammers Health PVT Ltd | Health & social care | 2013 |
| Samphire Developments (Norfolk) Ltd | Extraterritorial | 2010 |
| Samphire Electrical Services Ltd | Construction | 2026 |
| Samphire Publishing Limited | Professional & scientific | 2014 |
| Sample Drop Ltd | Wholesale & retail | 2024 |
| Sampson N Co Ltd | Wholesale & retail | 2015 |
| Samra & Gill Ltd | Wholesale & retail | 2008 |
| Sams & Wills Workwear Manufacturer Ltd | Manufacturing | 1998 |
| Sams (Norwich) Ltd | Real estate | 2015 |
| Sams Fabrications Ltd | Administrative & support | 2011 |
| Samson Security Solutions Ltd | Administrative & support | 2024 |
| Samuel Gedge Ltd | Wholesale & retail | 2006 |
| Samuel Health Care Ltd | Health & social care | 2019 |
| Samuel Ijaopo II Ltd | Real estate | 2023 |
| Samuel Ijaopo Ltd | Real estate | 2021 |
| Samuel James Norfolk Ltd | Hospitality | 2023 |
| Samuel JT Carpentry and Joinery Limited | Construction | 2023 |
| Samuel Martins Ltd | Real estate | 2018 |
| Samuel Poulton Properties Ltd | Construction | 2014 |
| Samuel Thomas Art Ltd | Arts & recreation | 2021 |
| Samui Property Ltd | Real estate | 2025 |
| Samurai International Holdings Ltd | Manufacturing | 2003 |
| Samurai Training Ltd | Education | 2017 |
| SAN Michele Financial Ltd | Professional & scientific | 2021 |
| Sana Brow Studio Ltd | Other services | 2019 |
| Sana Minimarket Ltd | Wholesale & retail | 2019 |
| Sanaku Limited | Health & social care | 2024 |
| Sanandas Ltd | Financial services | 2022 |
| Sanba Estate Ltd | Real estate | 2025 |
| Sanchez Sanchez Ltd | Health & social care | 2012 |
| Sanctuary Garden CIC | Agriculture & fishing | 2025 |
| Sanctuary Property Investments Limited | Real estate | 2018 |
| Sanctuary Search Limited | Administrative & support | 2012 |
| Sanctum Investments Ltd | Real estate | 2020 |
| Sand Events Ltd | Hospitality | 2023 |
| Sand Prix Ltd | Manufacturing | 2023 |
| Sandelson Stone Limited | Information & communication | 2015 |
| Sanders Boutcher Medicolegal Ltd | Health & social care | 2012 |
| Sanderson Advisory Ltd | Information & communication | 2025 |
| Sandpiper Cottages Limited | Real estate | 2020 |
| Sandra Reynolds Limited | Administrative & support | 2013 |
| Sands Fitting Ltd | Construction | 2026 |
| Sandstone Studio Limited | Professional & scientific | 2025 |
| Sandy Domestic Services Limited | Administrative & support | 2025 |
| Sanga and Sons Limited | Wholesale & retail | 2024 |
| Sanga Retail Ltd | Wholesale & retail | 2016 |
| Sangeeth Group Limited | Hospitality | 2024 |
| Sangen EDU Ltd | Education | 2024 |
| Sango Air Conditioning and Heating (London) Limited | Construction | 2017 |
| Sanitary OWL Ltd | Wholesale & retail | 2013 |
| Sanitec Cleaning Services Limited | Administrative & support | 2020 |
| Sans Property Ltd | Real estate | 2025 |
| Sansoni Healthcare Limited | Health & social care | 2015 |
| Santhilea London Limited | Wholesale & retail | 2011 |
| Santos-Edgar Properties Ltd | Real estate | 2022 |
| Santé Foods Ltd | Extraterritorial | 2019 |
| Saoi Ltd | Professional & scientific | 2021 |
| Saphe Services Ltd | Real estate | 2023 |
| Saphire Private Ltd | Hospitality | 2023 |
| Sapley Park Farms Limited | Agriculture & fishing | 1980 |
| Sapling Brand & Marketing Ltd | Professional & scientific | 2023 |
| Saplings Day Nursery (Midlands) Limited | Health & social care | 2011 |
| Sapogenik Limited | Wholesale & retail | 2024 |
| Saporita (Norwich) Ltd | Hospitality | 2016 |