| Salon Distribution Concepts Limited | Wholesale & retail | 2017 |
| Salop Automobiles Limited | Wholesale & retail | 2017 |
| Salop Heating Ltd | Construction | 2019 |
| Salop Rentals Limited | Real estate | 2019 |
| Salops Ltd | Wholesale & retail | 2023 |
| Salsette Court Management Company Limited | Households | 2008 |
| Salt Room City Ltd | Health & social care | 2024 |
| Salterns Management Company Limited | Real estate | 2009 |
| Salts Group Limited | Construction | 2020 |
| Salty Dog Group Ltd | Financial services | 2021 |
| Salty Yachts (Production) Limited | Construction | 1979 |
| Salveo Healthcare Ltd | Extraterritorial | 2016 |
| SAM and GEZ Properties Limited | Real estate | 2023 |
| SAM Convenience Store Ltd | Wholesale & retail | 2016 |
| Sam's Property Investements Limited | Real estate | 2025 |
| Sam's Silly Trinket Shop Ltd | Wholesale & retail | 2023 |
| Sama Play Cafe Ltd | Hospitality | 2024 |
| Samarpan Nrithyalaya Limited | Other services | 2018 |
| Sambrook Hall Management Limited | Households | 2020 |
| Samepage Property Services Ltd | Real estate | 2024 |
| Samko Limited | Wholesale & retail | 2005 |
| Sammy-Joe Stanton Ltd | Health & social care | 2023 |
| Samow Limited | Professional & scientific | 2020 |
| Sampsecom Ltd | Wholesale & retail | 2023 |
| Samrob Properties Limited | Real estate | 2024 |
| Samyra PVT Limited | Health & social care | 2023 |
| Sam’S K9 Services Ltd | Agriculture & fishing | 2022 |
| SAN Electrical Limited | Construction | 2013 |
| SAN Power and Controls Limited | Construction | 2024 |
| Sandbanks Apartments Management Company Limited | Households | 2013 |
| Sandell Partnership Ltd | Financial services | 2024 |
| Sandford Garage Limited | Wholesale & retail | 2023 |
| Sandham Davies & Jones Limited | Financial services | 2002 |
| Sandhills Management Consultancy Limited | Other services | 2009 |
| Sandlands Management Company (IOW) Limited | Households | 2005 |
| Sandlands Management Company Limited | Households | 1989 |
| Sandon Court Management Company Limited | Real estate | 2020 |
| Sandpipers Residents Association Limited | Extraterritorial | 1987 |
| Sandringham House Cowes Management Limited | Real estate | 2000 |
| Sandrock Services Limited | Administrative & support | 1995 |
| Sanfire Estates Ltd | Construction | 2014 |
| Sanfire Property Management Ltd | Real estate | 2022 |
| Sanglier Consulting Limited | Extraterritorial | 2014 |
| Sankey Property Investments Ltd | Real estate | 2024 |
| Sans Souci & ST Peters Court Residents Management Company Ltd | Households | 2023 |
| Sant - James Properties Ltd | Real estate | 2025 |
| Santhos Limited | Wholesale & retail | 2021 |
| Santhoshapu Enterprises Ltd | Financial services | 2024 |
| Santiago Court RTM Company Limited | Administrative & support | 2013 |
| Sapphire Amber Ltd | Hospitality | 2023 |
| Sapphire and Carbuncle Energy Limited | Mining & quarrying | 2025 |
| Sapphire Holdings (IW) Limited | Construction | 2015 |
| Saquarius Limited | Health & social care | 2020 |
| Sara Lisa Beauty Limited | Other services | 2016 |
| Sarah Alexander PR Limited | Professional & scientific | 2025 |
| Sarah Finch Limited | Financial services | 2014 |
| Sarah Lewis Enterprises Ltd | Hospitality | 2017 |
| Sarah Smith Associate Limited | Health & social care | 2025 |
| Sarah's Salad and Baguette Bar Ltd | Hospitality | 2020 |
| Sarahjanesbakery Ltd | Wholesale & retail | 2025 |
| Sarangi Properties Ltd | Real estate | 2022 |
| Sarangis IT Consultancy Ltd | Information & communication | 2013 |
| Sarasota Holdings Limited | Professional & scientific | 2023 |
| Saratoga Springs Limited | Financial services | 2025 |
| Sardar Ventures Ltd | Wholesale & retail | 2026 |
| Sarisbury Green Management Company Limited | Households | 2015 |
| Sarlton Facilities (UK) Limited | Professional & scientific | 2008 |
| Saroor Ltd | Wholesale & retail | 2021 |
| Sartor Limited | Wholesale & retail | 2022 |
| SAS Window Films Ltd | Construction | 2013 |
| Sassari Properties Ltd | Real estate | 2015 |
| Sassify Media Ltd | Education | 2023 |
| Satellite Finance Book One Limited | Financial services | 2024 |
| Satellite Finance Limited | Financial services | 2008 |
| Sativus Holdings Ltd | Financial services | 2023 |
| Saturday Candy Ltd | Wholesale & retail | 2026 |
| Satvada Ltd | Information & communication | 2006 |
| Saucy Roots Ltd | Manufacturing | 2025 |
| Savaari Travels Ltd | Transport & logistics | 2025 |
| Savant Watches Ltd | Wholesale & retail | 2023 |
| Savda Ltd | Hospitality | 2021 |
| Savda Properties Ltd | Real estate | 2025 |
| Savda Real Estate Ltd | Real estate | 2025 |
| Savic UK Limited | Information & communication | 2023 |
| Savoy Court Management Limited | Households | 1986 |
| Saxon Corner (Emsworth) Management Company Limited | Households | 2019 |
| Saxonbeck Limited | Professional & scientific | 2008 |
| Saxtoft Security Services Ltd | Administrative & support | 2024 |
| SAY YES to Happy Inc Limited | Hospitality | 2018 |
| Saya Fish and Chips Ltd | Hospitality | 2025 |
| Sayed Tyres Ltd | Wholesale & retail | 2023 |
| SB Groundworks & Plant Ltd | Construction | 2025 |
| SB Savanna Tech Ltd | Information & communication | 2021 |
| SB2 Promotions Limited | Administrative & support | 2014 |
| SBA NT Ltd | Health & social care | 2020 |
| Sbapropertyservices Ltd | Real estate | 2016 |
| Sbplus International Limited | Wholesale & retail | 2024 |
| SBS Inns Ltd | Hospitality | 2019 |
| SBT Plumbing and Heating Ltd | Construction | 2018 |
| SBW Raptors Ltd | Arts & recreation | 2026 |