| Discount Direct Ltd | Wholesale & retail | 2025 |
| Discovering Equitable Solutions Ltd | Professional & scientific | 2021 |
| Discreet Living Group Ltd | Professional & scientific | 2026 |
| Distribution Skills Limited | Education | 2010 |
| Divdom Health and Social Care Ltd | Health & social care | 2026 |
| Divdom Services Limited | Transport & logistics | 2025 |
| Diversae Mentes Ltd | Administrative & support | 2011 |
| DJ & GC Camm & SON (Amusements) Ltd | Arts & recreation | 2016 |
| DJ Heaney Ltd | Administrative & support | 2023 |
| DJ Potts Limited | Wholesale & retail | 2014 |
| Djrevell Consultancy Ltd | Professional & scientific | 2026 |
| DJT Homes Limited | Construction | 2008 |
| DK Motorcycles Holdings Limited | Financial services | 2013 |
| DK Motorcycles Limited | Wholesale & retail | 2013 |
| DK USA Limited | Financial services | 2019 |
| DM Innovations Ltd | Professional & scientific | 2011 |
| DM Message Limited | Manufacturing | 1977 |
| DMJ Leavold Ltd | Financial services | 2024 |
| DMK Design and Build Ltd | Construction | 2026 |
| Dockspec Marine Limited | Professional & scientific | 2020 |
| Docsni Limited | Hospitality | 2022 |
| DOKITA99 Ltd | Health & social care | 2025 |
| Doma (NI) Limited | Agriculture & fishing | 2014 |
| Donard Developments Ltd | Construction | 2000 |
| Doran Precision Engineering Limited | Manufacturing | 2018 |
| Doslobitos Services Limited | Professional & scientific | 2021 |
| Dove Door Services Limited | Manufacturing | 2002 |
| DOW Business & Sales Consultancy Ltd | Wholesale & retail | 2025 |
| Dowding Developments Limited | Real estate | 2020 |
| Down Sports Therapy Limited | Health & social care | 2016 |
| Down to Earth Groundwork & Landscaping Ltd | Administrative & support | 2020 |
| Downey Construction Ltd | Construction | 2006 |
| Downpatrick Eats Ltd | Hospitality | 2024 |
| Downs Road Dental Surgery Ltd | Health & social care | 2023 |
| DPC Recruitment Solutions Ltd | Administrative & support | 2023 |
| DPH Dairy Services Limited | Wholesale & retail | 2011 |
| DR Jolley Limited | Health & social care | 2021 |
| DR Laura Ltd | Health & social care | 2023 |
| DR Lenin Vellaturi Ltd | Real estate | 2011 |
| DR Medical Services Limited | Health & social care | 2023 |
| DR Quick Move Ltd | Transport & logistics | 2026 |
| DR Utilities Ltd | Other services | 2019 |
| DR. G. Mcbride & Company Limited | Health & social care | 1990 |
| Dragonfly Venture Group Ltd | Manufacturing | 2011 |
| Drains 4 Less Limited | Professional & scientific | 2006 |
| Dream Home Flooring Ltd | Wholesale & retail | 2024 |
| Dreamscapelettingsne Ltd | Real estate | 2024 |
| Dreckly Lettings Limited | Real estate | 2023 |
| Drfc Properties Limited | Real estate | 2011 |
| Drii-Uk Ltd | Professional & scientific | 2026 |
| Drone Filming & Photography Ltd | Professional & scientific | 2021 |
| Droneworks UK Solutions Ltd | Wholesale & retail | 2023 |
| DRS D Gahir Limited | Real estate | 2016 |
| DRS Medicals Midlands Limited | Health & social care | 2021 |
| Drumee Estates Limited | Agriculture & fishing | 2017 |
| DSE Tech Limited | Administrative & support | 2019 |
| DSS Medical Services Limited | Health & social care | 2019 |
| Dssg Ventures Ltd | Administrative & support | 2025 |
| DT Offshore Services Limited | Professional & scientific | 2020 |
| DT Utilities Limited | Construction | 2015 |
| DTL Recruitment Limited | Administrative & support | 2019 |
| Duergar Films Ltd | Professional & scientific | 2022 |
| Dunamis Sports Limited | Wholesale & retail | 2014 |
| Dundrod Fuels Limited | Wholesale & retail | 2015 |
| Dundrum Butters Ltd | Wholesale & retail | 2025 |
| Dundrum Development Association Ltd | Administrative & support | 1997 |
| Dundrum Sports Facility Ltd | Construction | 2024 |
| Dunq-It Ltd | Manufacturing | 2025 |
| DUO Franchise Ltd | Hospitality | 2025 |
| DUO Installations Limited | Construction | 2009 |
| Dusk Interiors Limited | Other services | 2022 |
| DV Developments Ltd | Real estate | 2024 |
| DW Yacht Consultancy Limited | Professional & scientific | 2026 |
| DWB Design Ltd | Professional & scientific | 2006 |
| Dwell Accommodation Limited | Real estate | 2017 |
| Dysart School of Dance Limited | Arts & recreation | 2003 |
| Dzwonnik Trans Ltd. | Transport & logistics | 2018 |
| E J Lundy & Co Ltd | Construction | 2013 |
| E&A Cleaning Limited | Administrative & support | 2025 |
| E&M Building Solutions Limited | Construction | 2023 |
| E-Trade Direct Limited | Construction | 2012 |
| E.L.T Property Consulting Ltd | Professional & scientific | 2026 |
| E.R.K. Engineering Ltd | Manufacturing | 2010 |
| Eadwell Homes Ltd | Health & social care | 2025 |
| Eagleaxe Apparels Limited | Wholesale & retail | 2024 |
| Eardley (UK) Ltd | Transport & logistics | 2000 |
| East Coast Restaurants Ltd | Wholesale & retail | 2007 |
| East European Jewish Heritage Project | Extraterritorial | 1997 |
| Eastcroft Construction Limited | Construction | 1983 |
| Eastern Takeaway Ltd | Hospitality | 2025 |
| Easy Animal Ltd | Manufacturing | 2018 |
| Easy Liquidation Limited | Extraterritorial | 2020 |
| Easy Logistics Group Ltd. | Transport & logistics | 2019 |
| Easy Shop Newcastle Limited | Wholesale & retail | 2025 |
| Eaton Acton Limited | Professional & scientific | 2013 |
| EBB Ltd | Professional & scientific | 2015 |
| Ebstar Limited | Information & communication | 2008 |
| Eclipse Lettings Ltd | Real estate | 2020 |
| Eco Cooker Conversions Ltd | Administrative & support | 2022 |
| Eco Interior Solutions Ltd | Construction | 2004 |