| Nutrifit Coaching Ltd | Health & social care | 2025 |
| O M C Barbecues Limited | Wholesale & retail | 1995 |
| O'Donnell Surveying Limited | Professional & scientific | 2016 |
| O'Neill Commercial Limited | Professional & scientific | 2014 |
| Oakleigh Elizabeth School of Dance Limited | Arts & recreation | 2026 |
| Oasis Hire Ltd | Administrative & support | 2022 |
| Oldfield Harp Ltd | Hospitality | 2024 |
| ON Demand Services Group Ltd | Water & waste | 2024 |
| One Health G-B Limited | Professional & scientific | 2019 |
| One Two Financial Training Limited | Education | 2022 |
| OPB Holdco Limited | Financial services | 2024 |
| Optic Fire Safety and Security Solutions Ltd | Administrative & support | 2020 |
| Optimus International Consultancy Limited | Professional & scientific | 2014 |
| OPY Ltd | Administrative & support | 2022 |
| Orchard Mead Holdings Limited | Wholesale & retail | 2013 |
| Oriental Flavour Ltd | Hospitality | 2025 |
| Orlando’S Dream Limited | Real estate | 2018 |
| Ornava Group Ltd | Information & communication | 2026 |
| OUT and About Window Cleaning NW Limited | Administrative & support | 2025 |
| Owens Roofing Solutions Ltd | Construction | 2026 |
| Oxton Developments Limited | Real estate | 2022 |
| P & a Services Wirral Ltd | Real estate | 2016 |
| P Weaver Services Ltd | Professional & scientific | 2019 |
| Palms and Pearls Limited | Information & communication | 2025 |
| Parkgate Stores 2019 Limited | Wholesale & retail | 2019 |
| Paul Dulac Photography Ltd | Professional & scientific | 2019 |
| PC Mortgage Solutions Limited | Financial services | 2014 |
| PCW Services Limited | Administrative & support | 2016 |
| PE Pharma Associates Limited | Professional & scientific | 2024 |
| Peakperformancelabs Limited | Information & communication | 2025 |
| Peco Industrial Silencers Ltd | Manufacturing | 2020 |
| Peninsula Group (Wirral) Ltd | Hospitality | 2014 |
| Peregrine Falcon Ltd | Information & communication | 2019 |
| Perfect Breaks Limited | Administrative & support | 2017 |
| Perks Projects Ltd | Arts & recreation | 2026 |
| Perpetual Engineering Partnerships Limited | Administrative & support | 2010 |
| Pest Research Hub Limited | Wholesale & retail | 2024 |
| Pet Habitat Limited | Wholesale & retail | 2012 |
| Pheromedica Limited | Professional & scientific | 2019 |
| Pheromonica Limited | Professional & scientific | 2019 |
| Phillip Bates & Co Financial Planning Limited | Financial services | 2020 |
| Phillip Bates & Co Limited | Professional & scientific | 1996 |
| Pilkington Leadership Limited | Professional & scientific | 2004 |
| Pitman Property Developments Limited | Real estate | 1959 |
| PJ Mitchell Developments Ltd | Real estate | 2025 |
| Pkfe Investments Ltd | Real estate | 2026 |
| Placerare Limited | Hospitality | 1987 |
| Ploughpalm Limited | | 1981 |
| Plumbcraft Tools Ltd | Wholesale & retail | 2021 |
| Pmcd Catering Limited | Hospitality | 2018 |
| Portal Trade UK Ltd | Professional & scientific | 2019 |
| Praxira Limited | Wholesale & retail | 2023 |
| Precise Projects Limited | Professional & scientific | 2007 |
| Precise Properties Limited | Real estate | 2013 |
| Premier Accident Repairs Limited | Wholesale & retail | 2012 |
| Premier Industrial Safety Ltd | Manufacturing | 2024 |
| Prenton Lawn Tennis Ground Company Limited(The) | Professional & scientific | 1891 |
| Present Day Publishing Limited | Information & communication | 2004 |
| Prestige Housing Developments Limited | Professional & scientific | 2017 |
| Prestige Housing Management Limited | Real estate | 2021 |
| Pretty Bridge Livery Ltd | Arts & recreation | 2022 |
| Prettypetalgifts Ltd | Wholesale & retail | 2021 |
| Price Commercial Management Limited | Professional & scientific | 2016 |
| Priory Croft Ltd | Professional & scientific | 2024 |
| Priory Nook Management Company Limited | Households | 2006 |
| Pro Scientia: Science and Engineering Consultancy Ltd | Professional & scientific | 2020 |
| Projected Ltd | Professional & scientific | 2005 |
| Properties SJH Limited | Real estate | 2025 |
| Property Aspire Ltd | Real estate | 2020 |
| Property Smiths Management Ltd | Real estate | 2023 |
| PS Motion Ltd | Information & communication | 2005 |
| Q Family and Professional Services Ltd | Public administration | 2024 |
| Q Mediation Ltd | Health & social care | 2023 |
| QA Oxton Ltd | Hospitality | 2019 |
| Quantum MPE Group UK Ltd | Professional & scientific | 2025 |
| Quercus Property Developments Limited | Construction | 2021 |
| R & D Davies & Co Ltd | Agriculture & fishing | 2024 |
| R & K Facilities Ltd | Construction | 2019 |
| R J M Training Services (UK) Ltd | Professional & scientific | 2010 |
| R&D Craft Interiors Ltd | Manufacturing | 2026 |
| R&R PUB Company Ltd | Hospitality | 2026 |
| Rachel Rozario Photography Limited | Professional & scientific | 2021 |
| Raine Hair and Beauty Limited | Other services | 2021 |
| Real Food Kitchen 365 Ltd | Hospitality | 2018 |
| Rebal Estates Limited | Real estate | 2002 |
| Recopile Limited | Professional & scientific | 2019 |
| Red DOT Wine Company Limited | Hospitality | 2014 |
| Red JAM Limited | Construction | 2007 |
| Red Open Limited | Construction | 2020 |
| Red Optimal Limited | Construction | 2002 |
| Red Rabbit Coaching Limited | Other services | 2023 |
| Red Rock Developments (NW) Ltd | Construction | 2023 |
| RED2 Systems Limited | Information & communication | 2017 |
| Redcliffe (TMH) Limited | Health & social care | 2018 |
| Redline Facades Limited | Professional & scientific | 2023 |
| Redstones Trading Limited | Wholesale & retail | 2020 |
| Regenology Ltd | Information & communication | 2006 |
| Release Fluid Technology Ltd | Extraterritorial | 2018 |
| Retain Wellbeing C.I.C. | Health & social care | 2019 |
| Richard J GUY Surgery Limited | Health & social care | 2002 |