| Liberte Legal Limited | Professional & scientific | 2024 |
| Liberty White Holdings Limited | Real estate | 2016 |
| Linda Bruce Limited | Other services | 2013 |
| Lindenwood Property Estates Limited | Real estate | 2020 |
| Lisa Morrison Photography Limited | Professional & scientific | 2025 |
| Lisava Holdings and Investments Ltd | Financial services | 2017 |
| Little Neston Express Ltd | Wholesale & retail | 2025 |
| Livdi Ltd | Real estate | 2024 |
| Liverpool Bicycle Limited | Wholesale & retail | 2009 |
| LJ Property Developments NW Ltd | Construction | 2022 |
| Lloyds Garage Repairs Ltd | Wholesale & retail | 2016 |
| Logratia Consulting Ltd | Professional & scientific | 2023 |
| Look Closer Ltd. | Extraterritorial | 2015 |
| Lovestitch (UK) Limited | Hospitality | 2013 |
| LWJ Medical Response Ltd | Health & social care | 2024 |
| M & a Property Limited | Real estate | 2015 |
| M & L Fencing Limited | Construction | 2002 |
| M Clements Property Limited | Real estate | 2025 |
| M Gibbs Enterprises Limited | Information & communication | 2015 |
| M.J.B. Project Management Ltd | Other services | 2007 |
| MA Environmental Consulting Limited | Professional & scientific | 2020 |
| MA Urology Ltd | Health & social care | 2024 |
| MAC & Co Plastering & Rendering Ltd | Construction | 2023 |
| Macglashan Retail Limited | Extraterritorial | 2012 |
| Mackintosh Health Ltd | Health & social care | 2023 |
| Made Simple (Team Building & Events) Ltd | Administrative & support | 2019 |
| Malhi Clinpharm Services Limited | Professional & scientific | 2025 |
| Mali Studios Limited | Wholesale & retail | 2019 |
| Malo Life Ltd | Wholesale & retail | 2025 |
| Manufab Ltd | Manufacturing | 2023 |
| Marcroft Catering and Events Limited | Hospitality | 2016 |
| Marintel Consultancy Ltd | Professional & scientific | 1999 |
| Mark Powell Scientific Limited | Professional & scientific | 2013 |
| Marsden Durrant Limited | Professional & scientific | 2006 |
| Marsh Motors (Neston) Limited | Wholesale & retail | 2016 |
| Mason Mclean Limited | Financial services | 2025 |
| Maturity Spirits (UK) Limited | Administrative & support | 2019 |
| Maullproperties Ltd | Real estate | 2026 |
| Maxam Services Ltd | Construction | 2020 |
| MB Cheshire Ltd | Wholesale & retail | 2025 |
| MB Consulting Services Ltd | Professional & scientific | 2020 |
| MB Parr Investments Limited | Real estate | 2023 |
| MBG Group Ltd | Financial services | 2024 |
| Mcfarlane Accounting Services Limited | Professional & scientific | 2015 |
| MCM Events Group Limited | Arts & recreation | 2019 |
| Mcmorran Entertainment Limited | Arts & recreation | 2019 |
| ME Weir Ltd | Health & social care | 2013 |
| Meadow View (Willaston) Management Company Limited | Households | 2022 |
| Mechemco UK Ltd | Wholesale & retail | 2025 |
| Medevtec Limited | Professional & scientific | 2019 |
| Medscope UK Limited | Health & social care | 2003 |
| Medtech AI Solutions Ltd | Professional & scientific | 2024 |
| Mellor & Brown Limited | Manufacturing | 2007 |
| Men's Social Network CIC | Health & social care | 2026 |
| Meyouandus Ltd | Arts & recreation | 2011 |
| MGC Solicitors Limited | Professional & scientific | 2012 |
| MI Resilience Ltd | Professional & scientific | 2018 |
| Mill Computer Support Ltd | Information & communication | 2014 |
| Millbank Management Consultancy Limited | Professional & scientific | 2011 |
| Miss MC of ALL Trades Ltd | Education | 2024 |
| MJN Bryan Limited | Construction | 2015 |
| ML Electrical and Home Maintenance Ltd | Construction | 2022 |
| MM Commercial Consultancy Ltd | Professional & scientific | 2023 |
| Modxgaming Ltd | Wholesale & retail | 2026 |
| Mouse Design Ltd | Manufacturing | 2013 |
| Moving Mountains Empowerment Group CIC | Arts & recreation | 2024 |
| MTF Consulting Limited | Information & communication | 2021 |
| Mudhouse Properties Limited | Real estate | 2021 |
| Multibuild Construction Ltd | Construction | 2024 |
| Mustard Seed Innovation Ltd | Financial services | 2019 |
| My Papillon Beauty Ltd | Other services | 2019 |
| Natural Pet Centre Limited | Wholesale & retail | 2012 |
| Neil Braithwaite Architect Ltd | Professional & scientific | 2008 |
| Neston Balloons, Cards and Gifts Limited | Wholesale & retail | 2013 |
| Neston Car Detailing Ltd | Other services | 2025 |
| Neston Clay Car Wash Ltd | Administrative & support | 2026 |
| Neston Clayhill Car Wash Ltd | Other services | 2025 |
| Neston Community Youth Centre Limited | Real estate | 2007 |
| Neston Complete Bathrooms and Plumbcraft Limited | Construction | 2015 |
| Neston Complete Bathrooms Ltd | Other services | 2025 |
| Neston Farm Ltd | Agriculture & fishing | 2021 |
| Neston High School | Education | 2012 |
| Neston Private Hire Ltd | Transport & logistics | 2011 |
| Neston Sunbeds and Beauty Limited | Other services | 2016 |
| Netwerk Ltd | Administrative & support | 2024 |
| Newark Fitness Ltd | Arts & recreation | 2016 |
| Newvision Windows & Doors Ltd | Construction | 2018 |
| Nick Green Ltd | Professional & scientific | 2022 |
| NJT Electrical Limited | Professional & scientific | 2014 |
| Nkms Consulting Ltd | Professional & scientific | 2018 |
| NO.1 Parkgate Ltd | Hospitality | 2023 |
| Nonstop Media Ltd | Extraterritorial | 2025 |
| Nordan Red Systems Ltd | Construction | 2006 |
| Normans Farm GAS Power Limited | Energy | 2016 |
| North Point One LLP | | 2009 |
| North West Control Cables Limited | Manufacturing | 2005 |
| NOT Just Fruit Limited | Wholesale & retail | 2010 |
| Notomorrow Ltd | Professional & scientific | 2025 |
| Novaworx Ltd | Administrative & support | 2018 |
| NSC Cost Management Services Ltd | Professional & scientific | 2018 |