| Seven Oceans Investment Ltd | Financial services | 2021 |
| Sevi Ltd | Construction | 2018 |
| Sevtone Limited | Other services | 2021 |
| SG Auto Centre Ltd | Wholesale & retail | 2021 |
| SH 2021 Ltd | Administrative & support | 2023 |
| SH Professional Tennis Ltd | Arts & recreation | 2022 |
| SHA BRO Store Ltd | Wholesale & retail | 2025 |
| Shah Care Services Ltd | Health & social care | 2022 |
| Shah Corporate Investments Ltd | Financial services | 2025 |
| Shahmeer Industries Limited | Wholesale & retail | 2023 |
| Shakir Traders Limited | Transport & logistics | 2024 |
| Shama Medical Services Limited | Health & social care | 2021 |
| Sharp Drive Heavy and Light Transport UK Ltd | Water & waste | 2022 |
| Shaukat and Sons Ltd. | Wholesale & retail | 2014 |
| Sheer Care Holdings Ltd | Real estate | 2024 |
| Sheer Care Services Limited | Health & social care | 2023 |
| Sheer Cleaning Ltd | Administrative & support | 2020 |
| Sheer Management Projects Limited | Extraterritorial | 2022 |
| Shezlin Construction & Joinery Ltd | Manufacturing | 2024 |
| Shezlin Ltd | Wholesale & retail | 2023 |
| Shifa Health Serivices Ltd | Health & social care | 2022 |
| Shilcock Properties Ltd | Real estate | 2022 |
| Shipzy Ltd | Wholesale & retail | 2025 |
| Shiroishi Commerce Ltd | Wholesale & retail | 2026 |
| Shop N Go Ltd | Wholesale & retail | 2024 |
| Shop to Go Nelson Ltd | Wholesale & retail | 2019 |
| Shoppy Mania Ltd | Wholesale & retail | 2024 |
| Short & Co Lawn Care Ltd | Administrative & support | 2024 |
| Shory Ltd | Other services | 2025 |
| Showizards Limited | Arts & recreation | 2025 |
| SHQ Nelson Ltd | Health & social care | 2021 |
| Shree Balaji Group Limited | Transport & logistics | 2016 |
| Sibes and Sled Dogs Husky Welfare Ltd | Other services | 2014 |
| Sibghah Nurverse Nexus CIC | Professional & scientific | 2025 |
| Signage Solution Partners Ltd | Wholesale & retail | 2025 |
| Signature Vehicle Soulutions Ltd | Wholesale & retail | 2025 |
| Siker Supplies Ltd | Wholesale & retail | 2025 |
| Silver Fern Property Ltd | Real estate | 2024 |
| Simon Business Ltd | Wholesale & retail | 2026 |
| Simon Edwards Ltd | Manufacturing | 2016 |
| Siraat Ltd | Real estate | 2018 |
| Siri Thai Massage Ltd | Other services | 2024 |
| SIS & Co Group Ltd | Hospitality | 2025 |
| Site Dynamics Ltd | Construction | 2025 |
| Sivaco Limited | Information & communication | 2012 |
| Sivone Limited | Wholesale & retail | 2019 |
| SJE Design & Build Ltd | Construction | 2022 |
| SK Medical Ltd | Health & social care | 2022 |
| SK Teeth Care Ltd | Health & social care | 2025 |
| Sky Companion Ltd | Administrative & support | 2018 |
| Skyblue Housing Limited | Real estate | 2018 |
| Skyline Auto Motors Ltd | Wholesale & retail | 2025 |
| Slaters Ices Limited | Wholesale & retail | 2026 |
| Slbpubmanagement Ltd | Hospitality | 2024 |
| SLH Incorporated Limited | Professional & scientific | 2025 |
| SM Coaching Services Limited | Other services | 2025 |
| SM Sofa 4 U Ltd | Manufacturing | 2025 |
| Sm&Wjt Limited | Health & social care | 2025 |
| Smale & Co Limited | Professional & scientific | 2025 |
| Smart Alarm System Ltd | Administrative & support | 2018 |
| Smart Choice Electricals Appliances Limited | Wholesale & retail | 2025 |
| Smart Energy Hub Ltd | Other services | 2023 |
| Smart Living Goods Ltd | Wholesale & retail | 2025 |
| Smart Office Furnishings Limited | Wholesale & retail | 2025 |
| Smart Productions NW Limited | Information & communication | 2023 |
| Smart Roofing SW Ltd | Construction | 2019 |
| Smartbuild Projects Ltd | Construction | 2016 |
| Smartcheck Mot&Services Ltd | Wholesale & retail | 2026 |
| Smartyplay Limited | Wholesale & retail | 2025 |
| Smash Boyz Ltd | Hospitality | 2024 |
| Smash EAT Group Ltd | Hospitality | 2024 |
| SMD Legal Ltd | Professional & scientific | 2022 |
| SMG Automotive Ltd | Wholesale & retail | 2023 |
| Smiles Party Venue Ltd | Real estate | 2024 |
| Smiley Valeting Limited | Administrative & support | 2021 |
| Snah Construction Ltd | Construction | 2025 |
| SNJ Holdings Limited | Financial services | 2022 |
| SNS Nelson Ltd | Wholesale & retail | 2016 |
| Snug City Limited | Wholesale & retail | 2010 |
| Soda Sommelier Ltd | Wholesale & retail | 2026 |
| Sofa & Co Atelier Ltd | Wholesale & retail | 2026 |
| Sofista Living Ltd | Wholesale & retail | 2025 |
| Software Counts Ltd | Information & communication | 2021 |
| Sohail Traders Ltd | Wholesale & retail | 2025 |
| Solani Travels Ltd | Administrative & support | 2026 |
| Solar Solutions NW Ltd | Construction | 2026 |
| Soldiers of the Damned Ltd | Information & communication | 2012 |
| Solidhub Limited | Wholesale & retail | 2013 |
| SOLVEIT4U Limited | Hospitality | 2024 |
| Somtex Limited | Wholesale & retail | 2001 |
| Sonic Travel Group Limited | Transport & logistics | 2023 |
| Sonya Trading Ltd | Wholesale & retail | 2022 |
| Sope Cash Registers Limited | Wholesale & retail | 2005 |
| Source Heating Limited | Construction | 2017 |
| Sourcelyn Limited | Wholesale & retail | 2026 |
| SOURCEPAY360 Ltd | Administrative & support | 2023 |
| Southfield Refurbishments Limited | Construction | 2024 |
| Southmore Management Ltd | Wholesale & retail | 2023 |
| Sovereign Home Installations Limited | Construction | 2024 |
| SP Care Ltd | Administrative & support | 2020 |