| Sandra's Solutions Limited | Financial services | 2026 |
| Sandspm Ltd | Professional & scientific | 2024 |
| Sandy Court Estate Management (Woburn) Limited | Households | 2014 |
| Sandy Court Leasehold Management (Woburn) Limited | Households | 2014 |
| Sandy FGC Ltd | Health & social care | 2026 |
| Sandy IT Ltd | Information & communication | 2022 |
| Sandy Retail Stores Ltd | Wholesale & retail | 2022 |
| Sandysol Limited | Administrative & support | 1999 |
| Sanfair Constructions Ltd | Construction | 2018 |
| Sangha Construction Group Ltd | Construction | 2024 |
| Sanil Shah Limited | Health & social care | 2024 |
| Sanity CCS Ltd | Administrative & support | 2024 |
| Sanjay Ltd | Transport & logistics | 2016 |
| Sanjugo Group Limited | Financial services | 2026 |
| Sankofa Care Solutions Limited | Health & social care | 2020 |
| Sankuc Limited | Wholesale & retail | 2018 |
| Sanober's Beauty Ltd | Other services | 2019 |
| Sanpra Limited | Wholesale & retail | 2014 |
| Sansetsu UK Limited | Manufacturing | 1978 |
| Sansom T Limited | Wholesale & retail | 2018 |
| Santa Heating & Plumbing Ltd | Construction | 2026 |
| Santa Maria UK Limited | Manufacturing | 1989 |
| Sante Essentials Limited | Manufacturing | 2021 |
| Santon Healthcare & Recruitment Limited | Health & social care | 2022 |
| Santrum UK Limited | Manufacturing | 2025 |
| Santwif Consultancy Limited | Financial services | 2020 |
| Santwipharma Limited | Wholesale & retail | 2026 |
| Sanwell Accounting Ltd | Professional & scientific | 2017 |
| Sanwell Properties Ltd | Real estate | 2019 |
| Sape Capital Ltd | Financial services | 2004 |
| Saplingot Ltd | Health & social care | 2022 |
| Saplings (Milton Keynes) Management Company Limited | Households | 1991 |
| Sapphire Core Holdings Ltd | Real estate | 2026 |
| Sapphire Executive Transfers Ltd | Transport & logistics | 2025 |
| Sapphire London RTW Ltd | Other services | 2025 |
| Sapphire Mechanical Engineering Services Ltd | Transport & logistics | 2015 |
| Sapphire Quarters Limited | Real estate | 2022 |
| Sapphire Scaffolding Limited | Construction | 2006 |
| Sapphire Scaffolding Services Limited | Administrative & support | 2009 |
| Sapphire Solutions Limited | Information & communication | 1994 |
| Sapphire Supply Limited | Administrative & support | 2014 |
| Sappro Solutions Ltd. | Information & communication | 2013 |
| Sapwells Limited | Construction | 2022 |
| SAR Driving School Ltd | Education | 2026 |
| Sara George Ltd | Professional & scientific | 2014 |
| Sara International Merchandising Limited | Wholesale & retail | 2023 |
| Saracen House (London Road) Management Company Ltd | Households | 2018 |
| Saracen Optical Ltd | Health & social care | 2018 |
| Saracens Wharf Management Company Limited | Households | 2005 |
| Sarah Halal Meat Limited | Wholesale & retail | 2016 |
| Sarah Ikumu Ltd | Arts & recreation | 2019 |
| Sarah Mcdonnell Design Limited | Arts & recreation | 2016 |
| Sarah Stanyer Limited | Administrative & support | 2021 |
| Sarah Wholesale & Retail Ltd | Wholesale & retail | 2023 |
| Sarang Consultancy Ltd | Information & communication | 2023 |
| Sarang Tradelink Limited | Wholesale & retail | 2024 |
| Saras Healthcare Infrastructure Limited | Real estate | 2021 |
| Sarath Consulting Limited | Professional & scientific | 2022 |
| Saraz Digital Ltd | Professional & scientific | 2014 |
| Saraz Group Ltd | Financial services | 2020 |
| Sara’S Shop Ltd | Wholesale & retail | 2023 |
| Sarchitek Limited | Information & communication | 2018 |
| Sarfraz & Naydenov Solicitors Ltd | Professional & scientific | 2023 |
| Saridogan Medical Services Limited | Health & social care | 2017 |
| Sario Ventures Ltd | Information & communication | 2017 |
| Sarjon Ltd | Wholesale & retail | 2019 |
| Sarma Enterprise Limited | Health & social care | 2014 |
| Sarmey Healthcare Limited | Financial services | 2010 |
| Saro International Limited | Hospitality | 2019 |
| Sarosiak Logistics Ltd | Administrative & support | 2018 |
| Sarsfield Engineering Ltd | Construction | 2026 |
| Sartain Medical Ltd | Health & social care | 2022 |
| Sarva Lakshmi Fashion Accessories Limited | Wholesale & retail | 2016 |
| Sarvagjna IT Consultancy Limited | Information & communication | 2018 |
| Sarvari Stays Ltd | Real estate | 2025 |
| SAS Environmental Limited | Water & waste | 2015 |
| SAS Housing Limited | Real estate | 2022 |
| SAS Solutions Private Ltd | Information & communication | 2014 |
| SAS Vision Assets Ltd | Wholesale & retail | 2022 |
| SAS Vision Ltd | Information & communication | 2015 |
| Sash Consultants Ltd | Real estate | 2011 |
| Sasha Sterling Enterprise Limited | Hospitality | 2020 |
| Sashtech Ltd | Information & communication | 2022 |
| Sass & Style Ltd | Professional & scientific | 2017 |
| Sassy Club Ltd | Wholesale & retail | 2023 |
| Sasu Limited | Wholesale & retail | 2021 |
| Satellite Information Services Limited | Information & communication | 2016 |
| Saththy Properties Limited | Real estate | 2025 |
| Sats AA Ltd | Real estate | 2024 |
| Sattar Homes Limited | Real estate | 2022 |
| Sattecco Limited | Wholesale & retail | 2023 |
| Sattvic Foods Ltd | Hospitality | 2018 |
| Saturn International Limited | Extraterritorial | 1987 |
| Sauls Place Limited | Other services | 2026 |
| Saunders Gardening Ltd | Professional & scientific | 2025 |
| Saurabh Bhardwaj Consulting Services Ltd | Professional & scientific | 2019 |
| Sausage Property Ltd | Real estate | 2020 |
| Sava Limited | Education | 1983 |
| Savage Music Limited | Other services | 1983 |
| Savan Consultancy Limited | Information & communication | 2007 |