| Stargate Capital LLP | | 2004 |
| Stark Intelligence Ltd | Information & communication | 2025 |
| Starlabz Ltd | Wholesale & retail | 2024 |
| Starman Strategies Ltd | Professional & scientific | 2023 |
| Starry Milky Vast Limited | Information & communication | 2025 |
| Startsell&Scalelondondigital Ltd | Wholesale & retail | 2025 |
| Startupworx Ltd | Information & communication | 2021 |
| Starway Ltd | Wholesale & retail | 2025 |
| State SIX News Limited | Information & communication | 2025 |
| Statera Beauty Ltd | Wholesale & retail | 2023 |
| Static Surge Ltd | Information & communication | 2025 |
| Stay Well Developments Ltd | Hospitality | 2020 |
| Stayzo Limited | Administrative & support | 2018 |
| Steady Steps Learning Hub Limited | Education | 2025 |
| Stealth Parts Limited | Wholesale & retail | 2023 |
| Steel Grove Ltd | Wholesale & retail | 2025 |
| Stefan Budde-Siegel Ltd | Financial services | 2025 |
| Stel Solutions Ltd | Professional & scientific | 2025 |
| Stella FX Ltd | Extraterritorial | 2025 |
| Stella Industrial Services Ltd | Wholesale & retail | 2026 |
| Stella Minds Ltd | Wholesale & retail | 2024 |
| Stellamirror AI Tech Limited | Information & communication | 2025 |
| Stellar Dealflow Limited | Real estate | 2025 |
| Stellar Globe Solution Ltd | Professional & scientific | 2024 |
| Stellar Inc Limited | Information & communication | 2023 |
| Step Digital Media Limited | Professional & scientific | 2021 |
| Steph French Consulting Ltd | Professional & scientific | 2023 |
| Sterling Constructions London Limited | Construction | 2023 |
| Sterling Trading Limited | Wholesale & retail | 2025 |
| Stewart & Omar Properties Ltd | Real estate | 2022 |
| Stewart Hill Law Limited | Professional & scientific | 2023 |
| Stigma Free Dating CIC | Professional & scientific | 2025 |
| Stillo Ltd | Wholesale & retail | 2025 |
| Stinky Little PIG Ltd | Professional & scientific | 2021 |
| Stir IT UP Cookery C.I.C. | Hospitality | 2018 |
| STJ Trading Company Ltd | Wholesale & retail | 2025 |
| Stock Hollow Limited | Wholesale & retail | 2026 |
| Stock Protector Ltd | Wholesale & retail | 2022 |
| Stockstar Wholesale Ltd | Wholesale & retail | 2023 |
| Stokeman Construction Ltd | Construction | 2017 |
| Stokes Homes Limited | Construction | 2018 |
| Stomp Ltd | Information & communication | 2025 |
| Stone & Barrow Holdings Ltd | Financial services | 2025 |
| Stone Key Inventories Ltd | Administrative & support | 2025 |
| Stone Rose Merchandise Ltd | Information & communication | 2023 |
| Stonebridge Civils Ltd | Construction | 2023 |
| Stonebridges Trading Ltd | Wholesale & retail | 2025 |
| Stonewick Holdings Limited | Real estate | 2026 |
| Stopbotleywest Campaign Ltd | Other services | 2024 |
| Storefrontbt Ltd | Wholesale & retail | 2022 |
| Storeit Selfstore Limited | Extraterritorial | 1998 |
| Storeoutlet Ltd | Wholesale & retail | 2022 |
| Storrs FOX Properties Ltd | Real estate | 2025 |
| Story Forge Games Limited | Information & communication | 2025 |
| Story Walks Ltd | Administrative & support | 2024 |
| Stott Transport Services Ltd | Transport & logistics | 2018 |
| Stpaid Ltd | Wholesale & retail | 2026 |
| Stpay Solutions Ltd | Wholesale & retail | 2026 |
| Strada Motors Limited | Extraterritorial | 2025 |
| Strangways & Co Ltd | Other services | 2024 |
| Strata Change Partners Ltd | Professional & scientific | 2018 |
| Stratagems Europe Limited | Professional & scientific | 2014 |
| Stratalyx Limited | Information & communication | 2024 |
| Stratberg Holding Ltd | Information & communication | 2026 |
| Strategik Vision Ltd | Information & communication | 2020 |
| Strategist Consultants Ltd | Financial services | 2024 |
| Strategy Agnostic Allocation Technology Limited | Information & communication | 2022 |
| Strategy Unit Wales Limited | Administrative & support | 2014 |
| Strathmore Trading Ltd | Real estate | 2025 |
| Stratiform Ltd | Professional & scientific | 2025 |
| Stratifyone Ltd | Information & communication | 2025 |
| Stratint Pacific Global Ltd | Information & communication | 2025 |
| Stratis Technologies Ltd | Information & communication | 2026 |
| Stream of Water CIC | Health & social care | 2023 |
| Streamups Software Ltd | Information & communication | 2026 |
| Strebla Coffee Roastery Ltd | Manufacturing | 2017 |
| Street Sign Studios Ltd | Information & communication | 2024 |
| Street to Summit Training Ltd | Education | 2021 |
| Strengths and Difference Ltd | Professional & scientific | 2026 |
| Stride Homes Ltd | Hospitality | 2025 |
| Stride Marketing Limited | Professional & scientific | 2016 |
| Stridewear Ltd | Wholesale & retail | 2025 |
| Striding Homes Ltd | Real estate | 2024 |
| Stripey Llama Ltd | Professional & scientific | 2017 |
| Strive Best Investments Limited | Real estate | 2026 |
| Strohm Holdings Ltd | Wholesale & retail | 2026 |
| Strolli Ltd | Wholesale & retail | 2025 |
| Strong MEN CRY Limited | Wholesale & retail | 2025 |
| Strukchr Ltd | Wholesale & retail | 2025 |
| Studenthub Coventry Limited | Education | 2025 |
| Studio 17 Ltd | Wholesale & retail | 2009 |
| Studio Builds Models Ltd | Professional & scientific | 2026 |
| Studio Damson Ltd | Administrative & support | 2024 |
| Studio Flow by Faye Limited | Arts & recreation | 2026 |
| Studio Mayala Ltd | Information & communication | 2025 |
| Studio Muse Ltd | Hospitality | 2025 |
| Studio Nellis Limited | Administrative & support | 2018 |
| Studio Odder Ltd | Arts & recreation | 2019 |
| Studio Spelugues Ltd | Information & communication | 2025 |
| STUDIO88 Dance Limited | Arts & recreation | 2024 |