| Studlands Company Limited | Financial services | 1987 |
| Study Saver Ltd | Information & communication | 2026 |
| Study to Succeed Network Ltd | Wholesale & retail | 2025 |
| Stumbl AI Ltd | Information & communication | 2025 |
| Stumpy's Singles Ltd | Wholesale & retail | 2026 |
| Stux Group Ltd | Information & communication | 2021 |
| Style Your Size Limited | Wholesale & retail | 2020 |
| Stylewithjessy Limited | Manufacturing | 2025 |
| Suave Brat Ltd | Wholesale & retail | 2026 |
| SUB 10 Ltd | Education | 2018 |
| Subject Matter Collective Ltd | Professional & scientific | 2026 |
| Sublmi Ltd | Manufacturing | 2025 |
| Subtone Ltd | Professional & scientific | 2011 |
| Successflowst Ltd | Wholesale & retail | 2025 |
| Successus Consulting Limited | Professional & scientific | 2016 |
| Suffolk Clearance Group Ltd | Water & waste | 2023 |
| Suffolk Smarts Ltd | Wholesale & retail | 2010 |
| Sugar House Lettings Ltd | Real estate | 2025 |
| Sugus & Giraffes Ltd | Wholesale & retail | 2022 |
| SUI Generis Jeans Limited | Wholesale & retail | 2023 |
| Suiter-Ai Ltd | Information & communication | 2026 |
| Sulfur Limited | Information & communication | 2024 |
| Sultanate of Sulu and North Borneo Ltd. | Extraterritorial | 2020 |
| Summer Springs Properties Ltd | Real estate | 2025 |
| Summit Games Ltd | Information & communication | 2022 |
| Sumo House Limited | Real estate | 2025 |
| Sumo Sushi Limited | Hospitality | 2011 |
| Sumod Group Ltd | Financial services | 2026 |
| Sumotwu Ltd | Wholesale & retail | 2025 |
| Sun Media Ltd | Wholesale & retail | 2025 |
| Sunbeam Lotus Owners' Club Limited | Other services | 2002 |
| Suncreek (Whitley Bay) Limited | Real estate | 2007 |
| Sunday Grace Ltd | Wholesale & retail | 2025 |
| Sunday Jubilee Ltd | Wholesale & retail | 2025 |
| Sundervolt Ltd | Construction | 2022 |
| Sundip Kaur Hira Ltd | Health & social care | 2025 |
| Sundog BIO Ltd | Information & communication | 2025 |
| Sunesis Ministries Ltd | Information & communication | 2014 |
| Sunharvestv Ltd | Wholesale & retail | 2026 |
| Sunnydale Consultancy Services Limited | Wholesale & retail | 2018 |
| Sunshine Family Group Ltd | Real estate | 2024 |
| Sunshine Pro Ltd | Construction | 2025 |
| Sunshine Project 01 Limited | Construction | 2021 |
| Sunyani Electronics Ltd | Manufacturing | 2021 |
| Sunyani Networks Ltd | Wholesale & retail | 2020 |
| Super 6 Digital Limited | Information & communication | 2024 |
| Super Mercat 786 Limited | Construction | 2025 |
| Super Scriber Ltd | Wholesale & retail | 2024 |
| Superbright Systems Ltd | Information & communication | 2024 |
| Supercar Chauffeurs Limited | Administrative & support | 2026 |
| Superhero IT Ltd | Wholesale & retail | 2023 |
| Superior Class Ltd | Wholesale & retail | 2022 |
| Supermac Property Solutions Ltd | Real estate | 2024 |
| Supply Energetics UK Limited | Public administration | 2026 |
| Supporting Adults Independent Living Service (Sails) Ltd. | Health & social care | 2026 |
| Supra Cargo Limited | Transport & logistics | 2024 |
| Supreme Culture Media Co Ltd | Wholesale & retail | 2025 |
| Surgeoneer Ltd | Manufacturing | 2025 |
| Surpriseboxx Limited | Wholesale & retail | 2023 |
| Sushi Boat Ltd | Hospitality | 2025 |
| Sussex Driving Lessons Ltd | Information & communication | 2025 |
| Sussex Microslides Ltd | Professional & scientific | 2024 |
| Sustainable Building Services Design Ltd | Professional & scientific | 2023 |
| Sustainable Synergy Ltd | Professional & scientific | 2024 |
| Sustainable, Inc. Ltd | Wholesale & retail | 2024 |
| Sutton Mill Properties Limited | Real estate | 2026 |
| Suxi Living Ltd | Wholesale & retail | 2026 |
| Suzan Aslan CIC | Health & social care | 2026 |
| Svecom Ltd | Wholesale & retail | 2025 |
| Svelte Living Ltd | Hospitality | 2017 |
| Sveltro Ltd | Wholesale & retail | 2025 |
| Svez Ltd | Wholesale & retail | 2023 |
| SVJ Consulting Ltd | Professional & scientific | 2025 |
| Svjc Distributions Ltd | Wholesale & retail | 2026 |
| SVM Goods for Good Ltd | Wholesale & retail | 2025 |
| Svosva Ltd | Wholesale & retail | 2018 |
| SW Music AV Ltd | Arts & recreation | 2025 |
| SW Music Ltd | Arts & recreation | 2024 |
| Swan Automotive Ltd | Real estate | 2024 |
| Swanry Ltd | Wholesale & retail | 2024 |
| Swanson Landscapes Limited | Administrative & support | 2015 |
| Swap Backlink Limited | Information & communication | 2025 |
| Swapauto Ltd | Wholesale & retail | 2023 |
| Swaplets Ltd | Wholesale & retail | 2025 |
| Swash Stock Limited | Wholesale & retail | 2026 |
| Swasto Traders Ltd | Wholesale & retail | 2018 |
| Swat Geotechnical Ltd | Construction | 2025 |
| Sweeku Limited | Wholesale & retail | 2025 |
| Sweepstarz Ltd | Arts & recreation | 2024 |
| Sweet Sparrow Ltd | Wholesale & retail | 2026 |
| Sweetsilk Ltd | Wholesale & retail | 2026 |
| Swerve Medical Limited | Other services | 2024 |
| Swift CUT Media Limited | Information & communication | 2025 |
| Swift Sprout Limited | Wholesale & retail | 2025 |
| SWIFT4REPAIRS Ltd | Other services | 2024 |
| Swiftcom UK Ltd | Wholesale & retail | 2023 |
| Swiftofferpropertysolutions Ltd | Professional & scientific | 2026 |
| Swiiift Limited | Transport & logistics | 2021 |
| Swinance Ltd | Real estate | 2024 |
| Swiss International Investment AG Ltd | Real estate | 2024 |