| Packco Handling Limited | Water & waste | 2006 |
| Pawel Smigielski Ltd | Manufacturing | 2020 |
| Paws and More Ltd | Wholesale & retail | 2022 |
| Payments Company Limited | Financial services | 2006 |
| PCC Electrical Contractors Ltd | Construction | 2015 |
| PCF Property Services Ltd | Real estate | 2022 |
| Pelefon Ltd | Wholesale & retail | 2014 |
| Penn Globe Limited | Professional & scientific | 2015 |
| Penn-White Limited | Manufacturing | 2005 |
| Pennwhite Print Solutions Limited | Manufacturing | 2012 |
| Pentagon Sport (Cheshire) Ltd | Arts & recreation | 2014 |
| Pentagon Sport Limited | Construction | 1998 |
| Pentagon+ Limited | Construction | 2023 |
| Personalised Gifts Online Ltd | Wholesale & retail | 2014 |
| Peter Forshaw Funeral Services Limited | Other services | 2011 |
| Pharmaphase Ltd | Information & communication | 2009 |
| Phil Clewes Joinery Limited | Manufacturing | 2013 |
| Phil Davies Plastering Ltd | Construction | 2013 |
| Pinseeker (UK) Limited | Manufacturing | 2004 |
| Piper Demolition & Asbestos Removal Ltd | Construction | 2023 |
| Plot OUT Loud Ltd | Information & communication | 2025 |
| POLISHED2PERFECTION Ltd | Administrative & support | 2017 |
| POM Digital Ltd | Professional & scientific | 2022 |
| Poppyham Ltd | Information & communication | 2024 |
| Positive Fire Safety Management Limited | Public administration | 2024 |
| Positively Different Solutions Limited | Administrative & support | 2018 |
| Poziflex Limited | Manufacturing | 2022 |
| Prisma Design Support Ltd | Professional & scientific | 2010 |
| Professional Education in Practice Limited | Education | 2009 |
| Professional Education in Practice Training Centre Limited | Education | 2009 |
| Puddleditch Ltd | Wholesale & retail | 2023 |
| Pulse Travel Limited | Professional & scientific | 2021 |
| Pure Pressure Ltd | Other services | 2025 |
| Purplesquare Hire Limited | Administrative & support | 2024 |
| Pyramid Property Development Limited | Administrative & support | 2003 |
| QB Projects Limited | Information & communication | 2017 |
| QC 1-6 RTM Company Limited | Households | 2025 |
| Qualisys Ltd | Professional & scientific | 2018 |
| R G & M E Street & SON Limited | Transport & logistics | 2002 |
| R.C.L. Distribution Limited | Extraterritorial | 2005 |
| Rainy City Spirits Limited | Wholesale & retail | 2026 |
| Ravenscraig Management Limited | Households | 1997 |
| Rayr Limited | Wholesale & retail | 2023 |
| RC Automation Ltd | Professional & scientific | 2019 |
| RD Communications (Europe) Company Limited | Wholesale & retail | 2018 |
| RD Fast Food Limited | Hospitality | 2026 |
| Rdpropertymaintenanceservices Ltd | Construction | 2025 |
| Red Chilli Projects Limited | Professional & scientific | 2008 |
| Reliable Roofing & Guttering Ltd | Construction | 2025 |
| Reliable Roofing Solutions Ltd | Construction | 2025 |
| Resin Base Driveways Ltd | Administrative & support | 2026 |
| Resin Driveways Manchester Ltd | Construction | 2025 |
| Resin Driveways Showroom Limited | Construction | 2026 |
| Resin Pave Ltd | Construction | 2023 |
| Restysleep Ltd | Wholesale & retail | 2026 |
| Revelation Leisure Limited | Hospitality | 2018 |
| Revlimit Tuning File Services Ltd | Information & communication | 2022 |
| Revlimit Tuning Ltd | Wholesale & retail | 2020 |
| Ridgeway Components Limited | Wholesale & retail | 1989 |
| Right-Fit Recruitment Group Limited | Administrative & support | 2018 |
| Rightboard Limited | Other services | 2018 |
| Rightway Roofing Ltd | Construction | 2025 |
| Rilshaw Court Management Ltd | Households | 2024 |
| RNR Bespoke Spaces Ltd | Construction | 2022 |
| Rocco Stone Limited | Wholesale & retail | 2006 |
| Roddy Engineering Limited | Professional & scientific | 2013 |
| ROK Plumbing Supplies Ltd | Wholesale & retail | 2017 |
| Roof Cleaning Ltd | Construction | 2025 |
| Roofing and Driveway Solutions Ltd | Construction | 2025 |
| Rosie Hilditch Counselling Ltd | Administrative & support | 2023 |
| RST Automotive Services Ltd | Wholesale & retail | 2017 |
| Rural Holidays Ltd | Hospitality | 2024 |
| Russell & Glover Ltd | Arts & recreation | 2019 |
| Russell Etherington Services Limited | Administrative & support | 2015 |
| RZK Textiles Limited | Wholesale & retail | 2010 |
| S P Mart Ltd | Wholesale & retail | 2023 |
| Salinae Garden Design Ltd | Administrative & support | 2021 |
| Sandbach Autos Limited | Wholesale & retail | 2008 |
| Sarah E Pickles Limited | Other services | 2020 |
| Sarchinar Ltd | Other services | 2024 |
| SAS Farming Limited | Agriculture & fishing | 2013 |
| Savillex Life Sciences UK Limited | Financial services | 2023 |
| School of Ashtanga Cheshire Ltd | Other services | 2025 |
| Seymour Living Ltd | Real estate | 2022 |
| Shenandoah Cheshire Ltd | Arts & recreation | 2022 |
| Shoalpay & Co Ltd | Administrative & support | 2026 |
| Silkseeker Ltd | Wholesale & retail | 2025 |
| Silver Arrow Logistics Ltd | Transport & logistics | 1999 |
| Silver Arrow Recruitment Limited | Administrative & support | 2015 |
| SJC Electrical Solutions Limited | Construction | 2020 |
| Skinnypants Ltd | Hospitality | 2020 |
| Skull and Spanner Ltd | Wholesale & retail | 2013 |
| Slgjproperties Ltd | Households | 2025 |
| Smart Accountancy Limited | Professional & scientific | 2006 |
| Smartfit Nutrition Ltd | Health & social care | 2010 |
| SMH Photography Ltd | Professional & scientific | 2011 |
| Socratic Investments UK Limited | Wholesale & retail | 2018 |
| SOL Letting Ltd | Real estate | 2025 |
| SOL Siesta Ltd | Administrative & support | 2022 |
| Soul of Duke Coffee Ltd | Hospitality | 2025 |