| Edwards Building & Joinery Services Limited | Construction | 2018 |
| EEA Management Limited | Professional & scientific | 2012 |
| EEE Tekeste Ltd | Real estate | 2024 |
| EEU Education Limited | Education | 2024 |
| EF Contractors Ltd | Construction | 2024 |
| Ef&N Estates Ltd | Real estate | 2024 |
| EFG Joinery Ltd | Manufacturing | 2025 |
| EFJ Technical Services Limited | Manufacturing | 2018 |
| Efwan Ltd | Administrative & support | 2026 |
| EG Scaffolding and Safety Consultancy Ltd | Construction | 2025 |
| EGE Advisory Services Ltd | Financial services | 2024 |
| EGF Pubs Limited | Hospitality | 2018 |
| Eggett Engineering Ltd | Professional & scientific | 2017 |
| Egonrob Limited | Professional & scientific | 2007 |
| EHC Rail Ltd | Transport & logistics | 2024 |
| EIGHTY8 Design Limited | Professional & scientific | 2013 |
| Eimar Ltd | Hospitality | 2022 |
| Eips Property and Investment Ltd | Real estate | 2020 |
| EJD Instrumentation Ltd | Professional & scientific | 2024 |
| EJD Project Services Ltd | Professional & scientific | 2015 |
| EJH Tech Ltd | Construction | 2018 |
| Ejwsr Ltd | Real estate | 2025 |
| EJZ14 Group Limited | Hospitality | 2024 |
| Ek-Thetics Ltd | Health & social care | 2013 |
| Eklipz Limited | Other services | 1996 |
| EL Chapo Chicken Ltd | Hospitality | 2024 |
| EL Communications (London) Limited | Professional & scientific | 2019 |
| EL Luxury Ltd | Manufacturing | 2023 |
| El&P Electrical Lighting and Power Limited | Construction | 2013 |
| El-Roi Primus Limited | Real estate | 2025 |
| El-Setouhy Ltd | Wholesale & retail | 2025 |
| El-Tara Holdings Ltd | Financial services | 2022 |
| Elaaf Limited | Wholesale & retail | 2024 |
| Elad Industrial Ltd | Manufacturing | 2023 |
| Elcoate Bouncy Castle Ltd | Administrative & support | 2024 |
| Elcoate Recovery Limited | Transport & logistics | 2024 |
| Elders Plant Hire Limited | Administrative & support | 2005 |
| Elderwood Energy Ltd | Professional & scientific | 2022 |
| Eldon Lane Convenience Store Ltd | Wholesale & retail | 2019 |
| Electrical Building Services Limited | Construction | 2002 |
| Electrical Certification Services Ltd | Construction | 2018 |
| Electrical MD Ltd | Construction | 2024 |
| Electrogenius Ltd | Construction | 2025 |
| Elegance Hive Ltd | Wholesale & retail | 2023 |
| Elegance Photography Limited | Professional & scientific | 2010 |
| Elegant Interiors North East Limited | Wholesale & retail | 2025 |
| Elekon Ltd | Construction | 2024 |
| Elemech Limited | Construction | 1991 |
| Elevare Financial Limited | Financial services | 2025 |
| Elevate Group NE Limited | Other services | 2025 |
| Elevating Voices Community Interest Company | Information & communication | 2023 |
| Eleven Eleven Gaming Ltd | Arts & recreation | 2018 |
| Eleven Eleven Leisure Limited | Administrative & support | 2018 |
| Elgie Electrical Ltd | Construction | 2012 |
| Elias Contest Limited | Construction | 2022 |
| Eliezer’S Beauty World Ltd | Other services | 2025 |
| Elipsis Ltd | Extraterritorial | 2021 |
| Elisei Trading Limited | Wholesale & retail | 2020 |
| Elite Air Conditioning & Refrigeration Limited | Construction | 2008 |
| Elite Electrical Solutions (North East) Ltd | Energy | 2016 |
| Elite Excavations & Groundworks Limited | Construction | 2017 |
| Elite Futures Trading Ltd | Financial services | 2024 |
| Elite Orthopaedics Limited | Health & social care | 2024 |
| Elite Physique Limited | Arts & recreation | 2017 |
| Elite Scaffolding NE Ltd | Construction | 2023 |
| Elite Sporting Agencies Limited | Arts & recreation | 2022 |
| Elite Sporting Memorabilia Limited | Arts & recreation | 2024 |
| Elite Windows & Doors NE Ltd | Construction | 2025 |
| Eliteglazing&Repairs Ltd | Manufacturing | 2026 |
| Elitepro Care Ltd | Administrative & support | 2021 |
| Elixir Accountancy Limited | Professional & scientific | 2018 |
| Elixir Business Services Limited | Professional & scientific | 2012 |
| Elixir Life Holdings Limited | Financial services | 2018 |
| Eliza (NE) Ltd | Wholesale & retail | 2023 |
| Elizabeth Anne(Middlesborough)Limited | Wholesale & retail | 1967 |
| Elizabeth Collins Consultancy Ltd | Health & social care | 2017 |
| Elizabeth George Bridal Ltd | Administrative & support | 2011 |
| Elizabeth Stanton Consulting Ltd | Professional & scientific | 2019 |
| ELK Recording Co. Limited | Arts & recreation | 2017 |
| Ella Pizza ( Fishburn) Ltd | Hospitality | 2024 |
| Ella Vapes NE Ltd | Wholesale & retail | 2025 |
| Ellazar Painters Ltd | Construction | 2022 |
| Ellen Ltd | Manufacturing | 2016 |
| Ellephant Limited | Manufacturing | 2019 |
| Ellerbeck Investments Limited | Financial services | 2015 |
| Ellidir Ltd | Health & social care | 2026 |
| Ellie Fleming Mortgages & Protection Ltd | Financial services | 2025 |
| Elliot Marlon Ltd | Information & communication | 2024 |
| Elliott Global Group Limited | Financial services | 2023 |
| Elliott Global Services Ltd | Real estate | 2022 |
| Elliott Hall Properties Limited | Construction | 2023 |
| Elliotts Music School Limited | Education | 2015 |
| Ellwood Home Improvements Ltd | Professional & scientific | 2023 |
| ELM Consultancy Group Limited | Professional & scientific | 2024 |
| Elmorsymedica Ltd | Health & social care | 2024 |
| Elqasim Medix Ltd | Wholesale & retail | 2025 |
| ELR Developments Ltd | Construction | 2021 |
| Elsie's Ices Ltd | Wholesale & retail | 2026 |
| Elstob Land Limited | Real estate | 2023 |
| Elvit Digital Services Limited | Information & communication | 2025 |