| ST Helens Car Sales Ltd | Wholesale & retail | 2022 |
| ST Helens Specsavers Limited | Wholesale & retail | 1991 |
| ST Helens Visionplus Limited | Wholesale & retail | 1995 |
| ST Helens Windows Limited | Manufacturing | 2005 |
| ST Michaels Management Company (Liverpool) Limited | Households | 1990 |
| ST Pauls Secretaries Limited | Professional & scientific | 1991 |
| Stancelaw Ltd | Professional & scientific | 2022 |
| Stekat Limited | Professional & scientific | 2007 |
| Stenson Estates and Properties Limited | Real estate | 2006 |
| Stephen Travis Limited | Professional & scientific | 2002 |
| Steve Slinger Limited | Construction | 2003 |
| Stokers Holdings Limited | Financial services | 2004 |
| Stokers Limited | Wholesale & retail | 1935 |
| Stone Heaven Limited | Construction | 2006 |
| Stonebridge Motor Company Limited | Manufacturing | 2007 |
| Stride Alley Ltd | Information & communication | 2017 |
| Struct Your Socials Ltd | Information & communication | 2024 |
| Studio 57 Pilates Limited | Arts & recreation | 2025 |
| Substation Projects Management Limited | Construction | 2007 |
| Sunlight Properties Limited | Real estate | 1999 |
| Sunset Property Management Limited | Real estate | 1981 |
| Sunstream Limited | Real estate | 2001 |
| Super Wood Products Limited | Real estate | 1940 |
| Surefloor Limited | Construction | 2000 |
| Sureline Interiors Limited | Construction | 2006 |
| Sustec International Ltd | Professional & scientific | 2006 |
| Sutcliffe Projects Limited | Construction | 2001 |
| Sweets N Stuff Bouquets Ltd | Wholesale & retail | 2019 |
| Switchable Marketing Ltd | Professional & scientific | 2023 |
| Switched on Electrical Solutions Ltd | Construction | 2016 |
| Synergie Group Limited | Health & social care | 2018 |
| Synergyworking Limited | Information & communication | 2000 |
| T & J P Properties (Liverpool) Ltd | Real estate | 2002 |
| T. Hollis Limited | Wholesale & retail | 2004 |
| T.P. FAY (Kirkby) Limited | Manufacturing | 1978 |
| Tafelmusik Limited | Education | 1990 |
| Talbots Group Limited | Extraterritorial | 1998 |
| Tanzania Limited | Other services | 2003 |
| Taylorglass Limited | Construction | 2001 |
| TCA Marketing Limited | Professional & scientific | 2002 |
| TCS Group International Limited | Administrative & support | 2004 |
| Technical CAD. Limited | Information & communication | 1995 |
| Techsoft Properties Ltd | Real estate | 2020 |
| Teddie Toys Limited | Wholesale & retail | 2000 |
| Telstar Solutions Limited | Information & communication | 2004 |
| THE 1ST Northern Sign Company Limited | Manufacturing | 2003 |
| THE Design Company Ltd. | Professional & scientific | 1995 |
| THE Doghouse | | 1998 |
| THE Fallows Consultancy Limited | Administrative & support | 2006 |
| THE Glen Kingsway Limited Partnership | | 2004 |
| THE Grange (Leyland Road) Management Limited | Administrative & support | 2006 |
| THE Hair Shop (ST Helens) Limited | Other services | 2002 |
| THE Head Gardeners Limited | Administrative & support | 2003 |
| THE Informacist Limited | Information & communication | 2005 |
| THE Italian Club Limited | Hospitality | 2006 |
| THE Laurels (Huyton) Limited | Households | 2007 |
| THE Liverpool Institute for Performing Arts | Education | 1990 |
| THE Liverpool Wargames Association Limited | Real estate | 2004 |
| THE Nigerian Community Association | Other services | 1999 |
| THE Old Vicarage Management Company (ST. Helens) Ltd | Households | 2011 |
| THE Orrell Park & District Community Association | Other services | 2006 |
| THE Perfect Hamper Co. Limited | Professional & scientific | 1960 |
| THE Right Will Company Ltd | Professional & scientific | 2004 |
| THE Rivington Spice Co Ltd | Extraterritorial | 2017 |
| THE Southport Gate Co. Limited | Construction | 2001 |
| THE Spinal Unit Action Group | Health & social care | 2003 |
| THE Vantori Group Limited | Arts & recreation | 2019 |
| THE Whitefield Centre Ltd | Real estate | 1998 |
| THE Wirral BED Superstore Limited | Wholesale & retail | 1995 |
| Thermatex Wahl Europe Limited | Manufacturing | 1999 |
| Think Agile Limited | Information & communication | 2012 |
| Thrive Collaborative CIC | Education | 2026 |
| Tidy Group Limited | Professional & scientific | 1975 |
| Tisith Limited | Wholesale & retail | 2018 |
| TLC Medical Limited | Health & social care | 2010 |
| TOM Carroll Associates Limited | Professional & scientific | 2002 |
| TOM Tully (Tyre Services) Limited | Administrative & support | 1962 |
| Top Quality Seconds (Prescot) Limited | Wholesale & retail | 1978 |
| Tope Services Limited | Construction | 2020 |
| Topping Consultancy Limited | Professional & scientific | 2002 |
| Tosaf UK Limited | Manufacturing | 2009 |
| Totally Vending Limited | Wholesale & retail | 2004 |
| Town Mouse Ltd | Real estate | 2004 |
| Towtrail Ltd | Wholesale & retail | 2016 |
| TP FAY (Distribution) Ltd | Transport & logistics | 2011 |
| Tram Power Limited | Other services | 1993 |
| Tram Research Limited | Professional & scientific | 1992 |
| Transformers UK Limited | Manufacturing | 1990 |
| Treetops Day Nursery Limited | Health & social care | 2002 |
| Tressell Homes Ltd | Health & social care | 2018 |
| Trev Woodward Transport Limited | Transport & logistics | 2007 |
| Trio Entertainment Limited | Arts & recreation | 2007 |
| TRM Electronics Limited | Manufacturing | 1994 |
| Tuneside Limited | Construction | 1988 |
| Two 12 Consultancy Limited | Administrative & support | 2007 |
| Two 2 Nine Design Limited | Wholesale & retail | 2002 |
| Tyrer Ecological Consultants Ltd | Professional & scientific | 2017 |
| Tzcp Ltd | Transport & logistics | 2024 |
| UK Waste & Recycling Ltd | Manufacturing | 2004 |
| Uksv Holdings Company Ltd. | Financial services | 2010 |