| Sydnope Hall Apartments Limited | Real estate | 1987 |
| Sync-Pro Limited | Real estate | 2025 |
| Synchronicity II Ltd | Professional & scientific | 2013 |
| Synergy Fire Engineering Limited | Professional & scientific | 2012 |
| Synergy Fire Technologies Limited | Administrative & support | 2016 |
| Synergy Fund LLP | | 2009 |
| Systems Metier Limited | Information & communication | 2004 |
| T & a Ventures Limited | Wholesale & retail | 2017 |
| T a Statham Haulage Ltd | Transport & logistics | 2015 |
| T J Property Developments Limited | Construction | 2009 |
| T. Twigg Haulage Limited | Transport & logistics | 2011 |
| T.J. Mastin Electrical Limited | Construction | 2018 |
| T.J.Berry Holdings Limited | Financial services | 2024 |
| T1 Networks Ltd | Information & communication | 2022 |
| Tagg Lane Dairy Limited | Manufacturing | 2017 |
| Talisman Management Limited | Extraterritorial | 1992 |
| Tamerton Silverhill Limited | Construction | 2024 |
| Tannic Properties Ltd | Real estate | 2024 |
| Tansley Transport and Removals Ltd | Transport & logistics | 2022 |
| Tansley Wood Management Limited | Other services | 1992 |
| Tansley Wood Mills Limited | Real estate | 2010 |
| Tarry Fields Management Company Ltd | Real estate | 2017 |
| Taste of Lifetime Limited | Health & social care | 2025 |
| Tavox Limited | Professional & scientific | 2024 |
| Tawney House Management Company Limited | Households | 2006 |
| Tax Farm Limited | Agriculture & fishing | 2015 |
| Taylor Landmark Property Ltd | Real estate | 2021 |
| Taylor Mottershead Ltd | Real estate | 2021 |
| Taylor Mottershead Property Investments Limited | Real estate | 2025 |
| TD and PD Hardy Limited | Agriculture & fishing | 2008 |
| Teaghlaigh Solutions Limited | Real estate | 2024 |
| Team Play Limited | Extraterritorial | 2009 |
| Team Redline Racing Limited | Wholesale & retail | 1999 |
| Tech Dept Limited | Information & communication | 2004 |
| Technical Will Limited | Information & communication | 2015 |
| Technolog Group Limited | Financial services | 1995 |
| Technolog Holdings Limited | Financial services | 2000 |
| Technolog Limited | Manufacturing | 1981 |
| Techtrade Enterprises Limited | Construction | 1999 |
| Templar Media Ltd | Manufacturing | 2006 |
| Tentwentyseven Limited | Hospitality | 2013 |
| Terra Nova Consulting 2024 Ltd | Professional & scientific | 2003 |
| TH Services Handyman Ltd | Administrative & support | 2025 |
| Thailand NO. 1 Limited | Extraterritorial | 2005 |
| Thatchers Croft Limited | Households | 2017 |
| THE Ashford Arms Limited | Hospitality | 2005 |
| THE Aura Hub Ltd | Other services | 2021 |
| THE Bakewell Tart Company Ltd | Wholesale & retail | 2019 |
| THE Barley MOW Inn Limited | Hospitality | 2009 |
| THE Batemans Mill Ltd | Hospitality | 2024 |
| THE BED Centre (Derbyshire) Limited | Wholesale & retail | 2018 |
| THE Bentley Brook Brewing Co. Ltd. | Manufacturing | 2022 |
| THE Bespoke Orangery Ltd | Construction | 2019 |
| THE Boat Inn 1772 Ltd | Hospitality | 2024 |
| THE Brew House (Wirksworth) Ltd | Hospitality | 2014 |
| THE Care Review Ltd | Professional & scientific | 2021 |
| THE Cave Seafood Restaurant Ltd | Hospitality | 2025 |
| THE Chemical HUT Ltd | Manufacturing | 2007 |
| THE Close (Matlock) Management Company Limited | Real estate | 2011 |
| THE Coach Collective Ltd | Professional & scientific | 2021 |
| THE Connection Space C.I.C. | Education | 2017 |
| THE Cromford Community Centre Ltd | Hospitality | 2025 |
| THE Dales Retreat Company Ltd | Real estate | 2026 |
| THE Dental Brokers Ltd | Professional & scientific | 2024 |
| THE Derbyshire Environmental Trust Limited | Professional & scientific | 1997 |
| THE Derbyshire Federation for Mental Health | Health & social care | 2006 |
| THE Derbyshire PUB Company Ltd | Hospitality | 2024 |
| THE Derbyshire PUB Company NO3 Limited | Hospitality | 2025 |
| THE Derbyshire Steam Ploughing Company Limited | Manufacturing | 2008 |
| THE Derwent and WYE Valley Railway Trust Limited | Arts & recreation | 2004 |
| THE Dining Room (Wirksworth) Limited | Hospitality | 2023 |
| THE Driver Handbook Limited | Information & communication | 2024 |
| THE Energy Advisors Limited | Energy | 2000 |
| THE Enigma Group of Companies Ltd | Education | 2024 |
| THE Environmental Quality Mark Community Interest Company | Professional & scientific | 2012 |
| THE Family Tree B&B Ltd | Extraterritorial | 2021 |
| THE Faulkner Media Group Limited | Financial services | 2018 |
| THE Feather Star ALE House Limited | Hospitality | 2022 |
| THE Fishpond Matlock Ltd | Hospitality | 2014 |
| THE Fundraising Consultancy Ltd | Other services | 2010 |
| THE Garden Library Ltd | Wholesale & retail | 2025 |
| THE Grand Pavilion Limited | Arts & recreation | 2010 |
| THE Grand Pavilion Trading Company Ltd | Hospitality | 2016 |
| THE Greyhound Cromford Ltd | Hospitality | 2024 |
| THE Guardian Support Hub Ltd | Professional & scientific | 2025 |
| THE Guinea PIG Shop Ltd | Professional & scientific | 2021 |
| THE GUT Stuff Limited | Wholesale & retail | 2017 |
| THE Handbook Group Limited | Information & communication | 2018 |
| THE Hidden Forest CIC | Education | 2023 |
| THE Hive Community Hub CIC | Education | 2021 |
| THE House Project Limited | Real estate | 2015 |
| THE Husk Group Limited | Wholesale & retail | 2019 |
| THE Institute of Narrative Therapy | Other services | 2009 |
| THE Investment Office Limited | Financial services | 2024 |
| THE Little Yellow Boat Group Ltd | Professional & scientific | 2021 |
| THE Loaf Ltd | Manufacturing | 2008 |
| THE Mastic Asphalt Council Limited | Other services | 1968 |
| THE Matlock Glass Company Limited | Construction | 2010 |
| THE Mill (Matlock Green) Management Company Limited | Households | 2005 |
| THE Miners Standard Ltd | Hospitality | 2022 |