| Dilazak Group Ltd | Manufacturing | 2025 |
| Diomo Limited | Information & communication | 2012 |
| Dipayan ROY Associates Limited | Administrative & support | 2011 |
| Dipnoi Limited | Wholesale & retail | 1973 |
| Direct Chemicals Ltd | Construction | 2013 |
| Direct Wallpapers (Wholesale) Limited | Wholesale & retail | 2020 |
| Directors Association Limited | Extraterritorial | 2006 |
| Dirty Water Films Limited | Construction | 2016 |
| Disange Ltd | Real estate | 2025 |
| Discofrisco Ltd | Wholesale & retail | 2026 |
| Discount Magic Ltd | Wholesale & retail | 2024 |
| Distinctive Group International Ltd. | Professional & scientific | 2013 |
| Distribution Services Limited | Other services | 2006 |
| Ditton Design & Build Limited | Construction | 2022 |
| Divine Dance Championships Ltd | Arts & recreation | 2025 |
| Divine Home Properties Ltd | Real estate | 2026 |
| Divine Studio Limited | Extraterritorial | 2010 |
| Divya Saxena Limited | Administrative & support | 2020 |
| Diyecobox Ltd | Hospitality | 2025 |
| DJ Air Conditioning Ltd | Professional & scientific | 2019 |
| Djevents Entertainment Ltd | Arts & recreation | 2011 |
| DJM Entertainment Limited | Information & communication | 2009 |
| Djox Ltd | Information & communication | 2017 |
| DL Pure Magic Ltd | Arts & recreation | 2023 |
| DLD (UK) Haulage Ltd | Transport & logistics | 2019 |
| DM Group Ltd | Real estate | 2026 |
| DMC Electrical (Berkshire) Ltd | Construction | 2022 |
| DME Consulting Ltd | Information & communication | 2024 |
| DMM Scenery Ltd | Information & communication | 2018 |
| Dmrc Property Services Ltd | Households | 2025 |
| DMS Laser Profiles Limited | Manufacturing | 1997 |
| DMS Stainless Steel Fabrications Limited | Manufacturing | 1992 |
| Dmunatamba Limited | Health & social care | 2014 |
| DNA Plus Limited | Transport & logistics | 2024 |
| Dndaviation Limited | Professional & scientific | 2012 |
| DNP Properties Ltd | Construction | 2026 |
| Dobedo Holdings Ltd | Financial services | 2018 |
| Dobedo Investments Ltd | Information & communication | 2012 |
| Dobedo Projects Ltd | Wholesale & retail | 2018 |
| Dobedo Represents Ltd | Professional & scientific | 2019 |
| Dobie Digswell Limited | Other services | 1993 |
| Dodge Construction Ltd | Construction | 2025 |
| Dog Solutions Limited | Transport & logistics | 2025 |
| Doka Cleaning Services Ltd | Administrative & support | 2017 |
| Doka Commercial Limited | Real estate | 2025 |
| Dolanward Limited | Hospitality | 1983 |
| Dollz House Ltd | Other services | 2023 |
| Dominion 5 Limited | Real estate | 2023 |
| Domostone Ltd | Manufacturing | 2024 |
| Dong DAO Group UK Limited | Wholesale & retail | 2016 |
| Donutterie Limited | Manufacturing | 2018 |
| Doozers Construction Services Ltd | Manufacturing | 2023 |
| Dopamine Decor Limited | Professional & scientific | 2021 |
| Dorpek Ltd | Wholesale & retail | 2022 |
| DOT Perfume Ltd | Wholesale & retail | 2026 |
| Dotmel Solutions Limited | Professional & scientific | 2014 |
| Double a Consultancy (UK) Limited | Professional & scientific | 2010 |
| Double a Digital Limited | Information & communication | 2010 |
| Double D Commercial Property Services Ltd | Construction | 2023 |
| Double Dare Recordings Limited | Information & communication | 2012 |
| Doublehandful Ltd | Information & communication | 2025 |
| Douglas Technology Ltd | Information & communication | 1998 |
| Dounia Talentcuisine Ltd | Hospitality | 2024 |
| Douse Ltd | Wholesale & retail | 2025 |
| Doyle Plant Hire & Construction Limited | Other services | 2003 |
| DPC Refinish Ltd | Wholesale & retail | 2016 |
| DPG Consulting Limited | Professional & scientific | 2017 |
| DPI Graphics Ltd | Professional & scientific | 2014 |
| Dpmp Consulting Ltd | Professional & scientific | 2023 |
| DPP Consultancy Limited | Administrative & support | 2013 |
| DR Gryglicki & Crow Ltd | Health & social care | 2019 |
| DR JUR. Eberhard Klein Receiver Limited Partnership | | 2014 |
| DR RAI Limited | Health & social care | 2024 |
| DR Rosie’S Clinic Ltd | Health & social care | 2024 |
| Dragon Porter (UK) Limited | Wholesale & retail | 2012 |
| Drain Clearance UK Limited | Water & waste | 2022 |
| Draperco Ltd | Real estate | 2024 |
| Drbr Limited | Wholesale & retail | 2011 |
| Drbs East Limited | Construction | 2001 |
| DRC Contracting (Henley) Limited | Administrative & support | 2018 |
| Dream Gardens Limited | Administrative & support | 2012 |
| Drenk Ltd | Manufacturing | 2025 |
| DRH Arts Ltd | Arts & recreation | 2019 |
| Drive Hub Network Ltd | Transport & logistics | 2024 |
| Drivesense Limited | Education | 2008 |
| Driving Compliance Limited | Transport & logistics | 2013 |
| Drjjderma Ltd | Health & social care | 2016 |
| Droid Developments Ltd | Administrative & support | 2009 |
| Droso Perfumes Limited | Manufacturing | 2024 |
| DRR Tech Master Ltd | Administrative & support | 2017 |
| Dsnet Ltd | Information & communication | 2001 |
| Dsylexic Studio Ltd | Professional & scientific | 2024 |
| DT Careers Ltd | Professional & scientific | 2022 |
| DT Tuning & Development Ltd | Professional & scientific | 2025 |
| Dt.Sprays Ltd | Construction | 2020 |
| DTS Procutasp Ltd | Professional & scientific | 2009 |
| Dtsom Ltd | Education | 2025 |
| DUA Estates Ltd | Real estate | 2021 |
| Dublicious Food Limited | Hospitality | 2013 |
| DUM DUM Doughnuts Ltd | Manufacturing | 2010 |