| DB Technologies Limited | Information & communication | 2025 |
| DBS Building & Construction Ltd | Construction | 2022 |
| DC Bespoke Financial Planning Ltd | Financial services | 2021 |
| Dcota Services Limited | Manufacturing | 2015 |
| DCS Building Services Ltd | Construction | 2022 |
| DCS Services Ltd. | Construction | 2016 |
| DCW Holdco Ltd | Financial services | 2023 |
| DCW Management Limited | Other services | 2014 |
| DD Franchising INT Limited | Administrative & support | 2019 |
| DD Franchising UK Limited | Hospitality | 2018 |
| DD Robertson Limited | Hospitality | 2023 |
| Ddgroundworks Construction Ltd | Construction | 2015 |
| DE Boyz Consulting Limited | Professional & scientific | 2015 |
| DE Jager Consultancy Limited | Professional & scientific | 2013 |
| DE Jager Estates Limited | Real estate | 2025 |
| DE Lamerie Limited | Wholesale & retail | 1989 |
| DE Shelter Limited | Construction | 2015 |
| Dealgan Limited | Professional & scientific | 2026 |
| Dealmonkey Limited | Wholesale & retail | 2022 |
| Dean Growth Partners Limited | Professional & scientific | 2025 |
| Dean Marketing Communications Limited | Professional & scientific | 2006 |
| Deborah Louise Financial Planning Ltd | Financial services | 2020 |
| Debra Walmsley Consulting Limited | Professional & scientific | 2021 |
| Debtrak UK Limited | Financial services | 2010 |
| Decaux Limited | Real estate | 2010 |
| Decimo Accounting Ltd | Administrative & support | 2016 |
| Decimus Consulting Limited | Professional & scientific | 2022 |
| Deckor Group Ltd | Administrative & support | 2022 |
| Decreeregard Limited | Hospitality | 1996 |
| Dede Global Limited | Wholesale & retail | 2022 |
| Dedipower Managed Hosting Limited | Extraterritorial | 2003 |
| Deep Team Limited | Professional & scientific | 2018 |
| Deepti Mahoney Ltd | Professional & scientific | 2020 |
| Dekra Loss Adjusters and Surveyors Ltd | Financial services | 2002 |
| DEL Management Limited | Professional & scientific | 2010 |
| Deliciously French Ltd | Wholesale & retail | 1999 |
| Dell Wind Farm Limited | Energy | 2014 |
| Delmere Properties Ltd | Real estate | 2021 |
| Delmorgal Limited | Professional & scientific | 1932 |
| Delsa Consulting Ltd | Professional & scientific | 2025 |
| Delta Black Limited | Real estate | 2018 |
| Delta Global Energy Ltd | Professional & scientific | 2026 |
| Delux Deco Ltd | Wholesale & retail | 2011 |
| Demby-Wheeler Limited | Education | 2018 |
| Demike Ltd | Information & communication | 2012 |
| Demir Utility Group Limited | Construction | 2021 |
| Denimer Property Limited | Real estate | 2022 |
| Denisi Cafe Ltd | Hospitality | 2019 |
| Denizim Transport Limited | Transport & logistics | 2021 |
| Denmark Mews Property Management Company Limited | Households | 2023 |
| Denmark Street Motors Ltd | Wholesale & retail | 2025 |
| Denmark Studios Ltd | Information & communication | 2015 |
| Denmead Ltd | Health & social care | 2020 |
| Dental and Medical Financial Services Limited | Financial services | 2014 |
| Dental Nurse Training Solutions Limited | Education | 2025 |
| Dental Recruitment UK Ltd | Administrative & support | 2023 |
| Dentastic Limited | Health & social care | 2013 |
| Denton Direct Ltd | Wholesale & retail | 2024 |
| Denwal Press Ltd | Extraterritorial | 2006 |
| Derbz Ltd | Wholesale & retail | 2025 |
| Dermot Limited | Financial services | 2023 |
| Derwent Associates Limited | Professional & scientific | 2025 |
| Derwent Drive (Residents) Limited | Households | 2003 |
| Desborough College Academy Trust | Education | 2018 |
| Design Centric Limited | Professional & scientific | 2004 |
| Desimpel Brick Limited | Professional & scientific | 1981 |
| Dessi Bite Ltd | Hospitality | 2023 |
| Deverell Limited | Construction | 1979 |
| Devilish Designs Ltd | Information & communication | 2023 |
| Devine Flowers Limited | Wholesale & retail | 2019 |
| Devine Numbers Ltd | Construction | 2023 |
| Devon Concrete Works,Limited | Professional & scientific | 1933 |
| Devon Contract Waste Ltd | Water & waste | 1997 |
| Devondale Property Ltd | Real estate | 2002 |
| Devontrix Limited | Information & communication | 2014 |
| Devs Real Estate Ltd | Real estate | 2024 |
| Dewdrop Media Limited | Information & communication | 2012 |
| DF Telecoms Limited | Construction | 2024 |
| DFM Associates Limited | Professional & scientific | 2008 |
| DG Enterprises Limited | Administrative & support | 2012 |
| DGB Media Ltd | Professional & scientific | 2021 |
| DGLV23 Media Applications Ltd | Information & communication | 2024 |
| Dhawan Mukul Coaching and Consulting Ltd | Professional & scientific | 2024 |
| Diabetes Relax Limited | Professional & scientific | 2019 |
| Diamond Cars Valeting Ltd | Wholesale & retail | 2025 |
| Diamond Chauffeur Ltd | Transport & logistics | 2025 |
| Diamond Health Smile Tourism Limited | Administrative & support | 2024 |
| Dice Pharmaceutical Communications Group Ltd | Professional & scientific | 2025 |
| Diego Masciaga Limited | Professional & scientific | 2019 |
| Dig&Fix Ltd | Information & communication | 2011 |
| Digiparks Ltd | Administrative & support | 2017 |
| Digipartner Limited | Wholesale & retail | 2022 |
| Digital Cloudz Ltd | Information & communication | 2026 |
| Digital Harmony Ltd | Information & communication | 2021 |
| Digital Pilates Systems Ltd | Health & social care | 2024 |
| Digital Skills Ltd | Administrative & support | 2015 |
| Digital Space Ltd. | Extraterritorial | 1997 |
| Digitalcymon Limited | Professional & scientific | 2021 |
| Dila 19 Ltd | Hospitality | 2019 |
| DILA20 Ltd | Hospitality | 2020 |