| Srp-Rail. Ltd | Transport & logistics | 2025 |
| Stack Shop Limited | Wholesale & retail | 2022 |
| Stag Lettings Ltd | Real estate | 2019 |
| Stapleton House Limited | Health & social care | 2014 |
| Steele Industrial Services Ltd | Construction | 2024 |
| Steep Solutions Ltd | Other services | 2017 |
| Stefiload Trans Ltd | Transport & logistics | 2025 |
| Stephen Black Clairvoyant Ltd | Other services | 2022 |
| Sterling Cooper Draper Pryce Limited | Other services | 2016 |
| Stock IS Limited | Administrative & support | 2025 |
| Stonebrook Recruitment Limited | Administrative & support | 2019 |
| Straightener Show Limited | Administrative & support | 2025 |
| Straker Independent Financial Planning Ltd | Professional & scientific | 2022 |
| Streetfood Srilanka Ltd | Wholesale & retail | 2023 |
| Studio 54 Carpets Limited | Wholesale & retail | 2015 |
| Studio Solution Team Limited | Wholesale & retail | 2025 |
| Subterranean Mateer HDD Limited | Construction | 2025 |
| Summerhouses and Sheds Erect Ltd | Construction | 2021 |
| Sunflower Community Kitchen Community Interest Company | Hospitality | 2026 |
| Super Glazing Ltd | Manufacturing | 2025 |
| Super Spexs Ltd | Wholesale & retail | 2025 |
| Sustainable Homes Development Ltd | Construction | 2025 |
| Swalwell Cater Limited | Hospitality | 2024 |
| Swalwell Leisure Limited | Hospitality | 2021 |
| Swans Cafe Catering Ltd | Hospitality | 2022 |
| Swift Electrical and Security Systems Limited | Construction | 2019 |
| T&E Scaffolding Ltd | Construction | 2026 |
| T-Cag Limited | Professional & scientific | 2022 |
| T2 Health Ltd | Health & social care | 2015 |
| Tag-Tech Ltd | Information & communication | 2022 |
| Talisima Ltd | Financial services | 2023 |
| Tanning Studio Jarrow Limited | Other services | 2024 |
| Tanzarote Sun Studio Limited | Other services | 2024 |
| Taproot Marketing Limited | Other services | 2010 |
| Taygor Ltd | Real estate | 2023 |
| Tayhall Financial Services Limited | Professional & scientific | 2013 |
| Taylormade North East Limited | Construction | 2005 |
| Taylormade Property Developments North East Ltd | Real estate | 2019 |
| TAZ Foods Limited | Hospitality | 2019 |
| Tbmb Ltd | Wholesale & retail | 2016 |
| Tbsk Ltd | Wholesale & retail | 2016 |
| Tbss Ltd | Wholesale & retail | 2016 |
| Teendrive Limited | Education | 2009 |
| Tennyson House Freehold Company Limited | Hospitality | 2012 |
| Tennyson House Property Management Company Ltd | Hospitality | 2012 |
| Thai Spa Jarrow Ltd | Other services | 2022 |
| Thanksabunch.Com Limited | Wholesale & retail | 2017 |
| That ‘Kini Ltd | Wholesale & retail | 2025 |
| THE Broadway Salon NE Ltd | Other services | 2022 |
| THE Candle PIT Ltd | Manufacturing | 2023 |
| THE Creative Forge Group Ltd | Wholesale & retail | 2022 |
| THE Dutchy PUB Company Ltd | Hospitality | 2022 |
| THE Everstone Continuum Limited | Financial services | 2026 |
| THE GEN DIT Limited | Information & communication | 2021 |
| THE Hawkswood Group Ltd | Hospitality | 2022 |
| THE Inspection Group Ltd | Manufacturing | 2010 |
| THE Lash Studio North East Limited | Other services | 2019 |
| THE Lash Studio Training and Supplies Ltd | Other services | 2024 |
| THE Lawns Ryton Village Limited | Real estate | 1995 |
| THE Lord Nelson Allotment Assoc. Ltd | Agriculture & fishing | 2022 |
| THE New Inn 1730 Ltd | Hospitality | 2019 |
| THE Old Rectory B & B Ltd | Hospitality | 2019 |
| THE Purple Parsnip Ltd | Wholesale & retail | 2024 |
| THE Skin Rejuvenation Clinic (NE) Limited | Other services | 2017 |
| THE Straits Partnership Ltd | Real estate | 2025 |
| THE Sweatbox Limited | Arts & recreation | 2024 |
| THE Therapy Circle Community Interest Company | Health & social care | 2025 |
| THE Therapy Suite Limited | Other services | 2024 |
| THE Tyne and Wear South Federation of Womens Institutes | Other services | 2003 |
| THE Viking Tandoori Ltd | Hospitality | 2018 |
| THE Wood Butcher Limited | Manufacturing | 2021 |
| Theautotradehub Ltd | Financial services | 2021 |
| Thermographic Technology International Limited | Professional & scientific | 1997 |
| Timberline DIY Limited | Wholesale & retail | 1999 |
| TJB Group Commercial GAS & Heating Engineers Ltd | Construction | 2019 |
| TMB Neuro Ltd | Health & social care | 2026 |
| Tohac Ltd | Construction | 2025 |
| Toneally Ltd. | Manufacturing | 2017 |
| Tony's Golden Fish & Chips Limited | Hospitality | 2013 |
| Top Marks (NE) Ltd. | Administrative & support | 2017 |
| Top of the Tots Ltd | Health & social care | 2011 |
| Torretech Limited | Professional & scientific | 2024 |
| Tradebase Kitchens Ltd | Manufacturing | 2017 |
| Treadright Flooring Ltd | Construction | 2023 |
| Tri-Con Holdings Limited | Real estate | 2020 |
| Tritility Limited | Energy | 2019 |
| Truelay Landscapes Ltd | Professional & scientific | 2025 |
| Trunk Show UK Ltd | Real estate | 2021 |
| Twenty Four Seven Global Coatings Limited | Manufacturing | 2008 |
| Tyne & Wear Cleaning Services Limited | Administrative & support | 2025 |
| Tyne and Wear Fire Safety Services Ltd | Professional & scientific | 2024 |
| Tyne Bargains Ltd | Professional & scientific | 2013 |
| Tyne Campers Limited | Administrative & support | 2020 |
| Tyne Tees Forth Air Conditioning and Refrigeration Limited | Construction | 2011 |
| Tyneside Access Solutions Ltd | Professional & scientific | 2013 |
| Tyneside Construction Ltd | Construction | 2023 |
| Tyneside Fabrication Limited | Manufacturing | 2008 |
| Tyneside Standards Limited | Administrative & support | 1998 |
| Tyneside Waste Services Ltd | Water & waste | 2024 |
| UK Asbestos Specialists Ltd | Education | 2003 |